Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Elisabetta Mantuano"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract LDL Receptor-related Protein-1 (LRP1/CD91) binds diverse ligands, many of which activate cell-signaling. Herein, we compared three LRP1 ligands that inhibit inflammatory responses triggered by lipopolysaccharide (LPS), including: enzymatical
Externí odkaz:
https://doaj.org/article/c31b59cff4f44999a6c4969dc1801bc6
Autor:
Elisabetta Mantuano, Carlotta Zampieri, Pardis Azmoon, Cory B. Gunner, Kyle R. Heye, Steven L. Gonias
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Low-density lipoprotein receptor-related protein-1 (LRP1) functions as a receptor for nonpathogenic cellular prion protein (PrPC), which is released from cells by ADAM (a disintegrin and metalloproteinase domain) proteases or in extracellular vesicle
Externí odkaz:
https://doaj.org/article/afe55472c9374d5caabfd913552ed274
Autor:
Paola Pontecorvi, Michael A. Banki, Carlotta Zampieri, Cristina Zalfa, Pardis Azmoon, Maria Z. Kounnas, Cinzia Marchese, Steven L. Gonias, Elisabetta Mantuano
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants. Recent
Externí odkaz:
https://doaj.org/article/c67ad0f1890e467e9e9e93cdbf827933
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224738 (2019)
Tissue-type plasminogen activator (tPA) is a major activator of fibrinolysis, which also attenuates the pro-inflammatory activity of lipopolysaccharide (LPS) in bone marrow-derived macrophages (BMDMs) and in vivo in mice. The activity of tPA as an LP
Externí odkaz:
https://doaj.org/article/dbae6326c2dd496aa07ae915b6be1442
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186649 (2017)
LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs in the fields of vascular biology and neurobiology. How these
Externí odkaz:
https://doaj.org/article/91dab17c4c7b4c3f96008ac29187ce12
Autor:
Sounak Gupta, Andrew M Hau, Jordan R Beach, Jyoti Harwalker, Elisabetta Mantuano, Steven L Gonias, Thomas T Egelhoff, Donna E Hansel
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81081 (2013)
Bladder cancer is the fourth most common cause of cancer in males in the United States. Invasive behavior is a major determinant of prognosis. In this study, we identified mammalian target of rapamycin complex 2 (mTORC2) as a central regulator of bla
Externí odkaz:
https://doaj.org/article/b345ce0cad20471e905be159a2b5574c
Autor:
Kazuyo Yamauchi, Tomonori Yamauchi, Elisabetta Mantuano, Kenichi Murakami, Kenneth Henry, Kazuhisa Takahashi, Wendy Marie Campana
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75497 (2013)
Developing sensory neurons require neurotrophic support for survival, neurite outgrowth and myelination. The low-density lipoprotein receptor-related protein-1 (LRP1) transactivates Trk receptors and thereby functions as a putative neurotrophin. Here
Externí odkaz:
https://doaj.org/article/57893fb90a8846978d7da05175f677f5
Autor:
Cory B. Gunner, Pardis Azmoon, Elisabetta Mantuano, Lipsa Das, Carlotta Zampieri, Salvatore V. Pizzo, Steven L. Gonias
Publikováno v:
Journal of Cellular Biochemistry. 124:743-752
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6110e1f44dec6b644963ad1727be094
https://doi.org/10.1002/jcb.30401
https://doi.org/10.1002/jcb.30401
Autor:
Steven L. Gonias, Michael A. Banki, Pardis Azmoon, Haylie K. Romero, Christina J. Sigurdson, Elisabetta Mantuano, Wendy M. Campana
Publikováno v:
The Journal of biological chemistry. 298(3)
Exosomes and other extracellular vesicles (EVs) participate in cell-cell communication. Herein, we isolated EVs from human plasma and demonstrated that these EVs activate cell signaling and promote neurite outgrowth in PC-12 cells. Analysis of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c4f0163d916a8e741a5584c44998a3
https://pubmed.ncbi.nlm.nih.gov/35090893
https://pubmed.ncbi.nlm.nih.gov/35090893
Autor:
Wendy M. Campana, Michael A. Banki, Christina J. Sigurdson, Steven L. Gonias, Elisabetta Mantuano, Pardis Azmoon
Publikováno v:
J Immunol
Nonpathogenic cellular prion protein (PrPC) demonstrates anti-inflammatory activity; however, the responsible mechanisms are incompletely defined. PrPC exists as a GPI-anchored membrane protein in diverse cells; however, PrPC may be released from cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f17e27d0b0376d80676eaa6e7bf3934
https://pubmed.ncbi.nlm.nih.gov/34933943
https://pubmed.ncbi.nlm.nih.gov/34933943