Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Elisabetta Liverani"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Cancer incidence and mortality are growing worldwide. With a lack of optimal treatments across many cancer types, there is an unmet need for the development of novel treatment strategies for cancer. One approach is to leverage the immune system for i
Externí odkaz:
https://doaj.org/article/54164dd7590849d491f653b94e4d1701
Autor:
Emmanuel Boadi Amoafo, Philomena Entsie, Samara Albayati, Glenn P. Dorsam, Satya P. Kunapuli, Laurie E. Kilpatrick, Elisabetta Liverani
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Sepsis, a complex clinical syndrome resulting from a serious infection, is a major healthcare problem associated with high mortality. Sex-related differences in the immune response to sepsis have been proposed but the mechanism is still unknown. Puri
Externí odkaz:
https://doaj.org/article/4289becbc13c498f878d92b452f3030e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6709 (2023)
P2Y12 is a G-protein-coupled receptor that is activated upon ADP binding. Considering its well-established role in platelet activation, blocking P2Y12 has been used as a therapeutic strategy for antiplatelet aggregation in cardiovascular disease pati
Externí odkaz:
https://doaj.org/article/5636e986f89246f4a5cd80e7a835ae78
Autor:
Yuan Tang, Fariborz Soroush, Shuang Sun, Elisabetta Liverani, Jordan C. Langston, Qingliang Yang, Laurie E. Kilpatrick, Mohammad F. Kiani
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Abstract Background Neuroinflammation often develops in sepsis leading to activation of cerebral endothelium, increased permeability of the blood-brain barrier (BBB), and neutrophil infiltration. We have identified protein kinase C-delta (PKCδ) as a
Externí odkaz:
https://doaj.org/article/9f091d5655cd4b088b3c8f43be588711
Autor:
R Paul Wilson, Sarah A Tursi, Glenn J Rapsinski, Nicole J Medeiros, Long S Le, Kevin P Kotredes, Sajan Patel, Elisabetta Liverani, Shuang Sun, Wenhan Zhu, Laurie Kilpatrick, Sebastian E Winter, Ana M Gamero, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007745 (2019)
The mechanisms by which the gut luminal environment is disturbed by the immune system to foster pathogenic bacterial growth and survival remain incompletely understood. Here, we show that STAT2 dependent type I IFN signaling contributes to the inflam
Externí odkaz:
https://doaj.org/article/648625e4182d42e88ea88a6f56d5c0a6
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195379 (2018)
Sepsis is characterized by an intense systemic inflammatory response activating a cascade of proinflammatory events resulting in leukocyte dysregulation and host tissue damage. The lung is particularly susceptible to systemic inflammation, leading to
Externí odkaz:
https://doaj.org/article/fc9efd8e9e0043b784230d3bf81524b3
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182867 (2017)
It has long been postulated that Protein Kinase C (PKC) is an important regulator of megakaryopoiesis. Recent contributions to the literature have outlined the functions of several individual PKC isoforms with regard to megakaryocyte differentiation
Externí odkaz:
https://doaj.org/article/1a023385d43b47b7afeb8a2662732597
Autor:
Analia E Garcia, Mario C Rico, Elisabetta Liverani, Raul A DeLa Cadena, Paul F Bray, Satya P Kunapuli
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69093 (2013)
Administration of the thienopyridine P2Y12 receptor antagonist, clopidogrel, increased the erosive arthritis induced by peptidoglycan polysaccharide (PG-PS) in rats or by injection of the arthritogenic K/BxN serum in mice. To determine if the detrime
Externí odkaz:
https://doaj.org/article/0a71ca0799f24e84be65bfaa31aed4d6
Publikováno v:
Physiology. 38
Intra-abdominal sepsis is a life-threatening complex syndrome caused by dysregulation of the host response to infection and is one of the major complications of intra-abdominal surgery. To date, only supportive therapies such as ventilation support,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fece6bda037fb1307d33f98347fb653
https://doi.org/10.1152/physiol.2023.38.s1.5785322
https://doi.org/10.1152/physiol.2023.38.s1.5785322
Publikováno v:
J Cell Commun Signal
Platelets are well known for their roles in hemostasis and thrombosis, and are increasingly recognized for their abilities to interact with white blood cells during inflammatory diseases, via secreted soluble factors as well as cell–cell contact. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d935b945da097b1b2f3643e211bf52
https://doi.org/10.1007/s12079-022-00676-0
https://doi.org/10.1007/s12079-022-00676-0