Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elisabetta Fortini"'
Autor:
Enrico Tiacci, Gianluca Schiavoni, Maria Paola Martelli, Emanuela Boveri, Roberta Pacini, Alessia Tabarrini, Silvia Zibellini, Alessia Santi, Valentina Pettirossi, Elisabetta Fortini, Stefano Ascani, Luca Arcaini, Giorgio Inghirami, Marco Paulli, Brunangelo Falini
Publikováno v:
Haematologica, Vol 98, Iss 4 (2013)
The BRAF-V600E mutation defines genetically hairy cell leukemia among B-cell leukemias and lymphomas. In solid tumors, BRAF-V600E is known to aberrantly activate the oncogenic MEK-ERK pathway, and targeted BRAF and/or MEK inhibitors have shown remark
Externí odkaz:
https://doaj.org/article/dd19befec6bc4ec6b4818304288543d6
Autor:
Alessia Santi, Alessandra Pucciarini, Barbara Crescenzi, Simonetta Viviani, Ariele Rosseto, Laura Pasqualucci, Roberta Pacini, Raul Rabadan, Alex Penson, Brunangelo Falini, Simonetta Piattoni, Elisabetta Fortini, Erik Ladewig, Antonello Cabras, Barbara Bigerna, Alessandra Venanzi, Valentina Pettirossi, Cristina Mecucci, Yuchun Wang, Gianluca Schiavoni, Alessandro M. Gianni, Sofija Vlasevska, Alessia Tabarrini, Enrico Tiacci, Stefano Ascani
Publikováno v:
Blood. 131(22)
Dissecting the pathogenesis of classical Hodgkin lymphoma (cHL), a common cancer in young adults, remains challenging because of the rarity of tumor cells in involved tissues (usually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bad8ed99c120a8df0e02b1a311cad95
https://pubmed.ncbi.nlm.nih.gov/29650799
https://pubmed.ncbi.nlm.nih.gov/29650799
Autor:
Maria Paola Martelli, Alessia Santi, Guido Russo, Roberta Mannucci, Alessandra Pucciarini, Elisa Imperi, Ariele Spanhol-Rosseto, Brunangelo Falini, Elisabetta Fortini, Valentina Pettirossi, Enrico Tiacci, Gianluca Schiavoni, Barbara Bigerna, Ludger Klein-Hitpass, Paolo Sportoletti
Hairy cell leukemia (HCL) shows unique clinicopathological and biological features. HCL responds well to purine analogs but relapses are frequent and novel therapies are required. BRAF-V600E is the key driver mutation in HCL and distinguishes it from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384fd1805651d19f412921504a880294
Autor:
Erik Ladewig, Antonello Cabras, Alessandra Venanzi, Elisabetta Fortini, Simonetta Viviani, A. Penson, Raul Rabadan, Barbara Crescenzi, Laura Pasqualucci, Cristina Mecucci, Yuchun Wang, Gianluca Schiavoni, Alessandro M. Gianni, Enrico Tiacci, Ariele Spanhol-Rosseto, Brunangelo Falini
Publikováno v:
Blood. 128:1088-1088
Dissecting the genetics of classical Hodgkin lymphoma (cHL), a common lymphoma derived from germinal center B (GCB) cells, has remained a difficult task compared to other lymphomas, due to the rarity (usually Thus, we microdissected 1200-1800 single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71625fe3fd0959b6a0c61a5fc294c8da
https://doi.org/10.1182/blood.v128.22.1088.1088
https://doi.org/10.1182/blood.v128.22.1088.1088
Autor:
Alessia Santi, Alessia Tabarrini, Giorgio Inghirami, Emanuela Boveri, Elisabetta Fortini, Maria Paola Martelli, Silvia Zibellini, Marco Paulli, Enrico Tiacci, Stefano Ascani, Luca Arcaini, Valentina Pettirossi, Roberta Pacini, Gianluca Schiavoni, Brunangelo Falini
Abstract 2657 The BRAF-V600E mutation defines genetically hairy cell leukemia (HCL) among B-cell leukemias and lymhphomas. In solid tumors, BRAF-V600E is known to aberrantly activate the oncogenic MEK-ERK pathway, and targeted BRAF and/or MEK inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0743529e62bbfef6555fda632dc7fe35
http://hdl.handle.net/11391/1398072
http://hdl.handle.net/11391/1398072
Autor:
Barbara Bigerna, Valentina Pettirossi, Enrico Tiacci, Ildo Nicoletti, Maria Paola Martelli, Roberta Mannucci, Elisabetta Fortini, Guido Russo, Alessia Santi, Elisa Imperi, Alessandra Pucciarini, Brunangelo Falini
Publikováno v:
Blood. 122:3064-3064
Background Hairy cell leukemia (HCL) is a peripheral B-cell neoplasm with indolent clinical course and peculiar morphology and phenotype. Recently, we identified the BRAF-V600E kinase mutation as the genetic lesion underlying HCL and distinguishing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b31e7e02e9977461eb3bbd6ffae2de4a
https://doi.org/10.1182/blood.v122.21.3064.3064
https://doi.org/10.1182/blood.v122.21.3064.3064