Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elisabetta Falaschi"'
Autor:
Luisa Maresca, Samuele Lodovichi, Alessandra Lorenzoni, Tiziana Cervelli, Rossella Monaco, Laura Spugnesi, Mariella Tancredi, Elisabetta Falaschi, Katia Zavaglia, Elisabetta Landucci, Manuela Roncella, Caterina Congregati, Angiolo Gadducci, Antonio Giuseppe Naccarato, Maria Adelaide Caligo, Alvaro Galli
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatch repair (MMR) may contribute to breast and ovarian cancer development. Taking advantage the functional conservation of DNA repair pathways between ye
Externí odkaz:
https://doaj.org/article/e639c8c962944410837a5ab480c63c8e
Autor:
Cinzia Cosini, Francesca Spina, Caterina Congregati, Stefania Tommasi, Mariella Tancredi, Rosa Scarpitta, Enrico Tagliafico, Francesca Bellè, Tiziana Cervelli, Luisa Balestrino, Elisabetta Falaschi, Maria Grazia Tibiletti, Gaetana Gambino, Alvaro Galli, Eleonora Conti, Elena Tenedini, Marco Marino, Paolo Aretini, Ileana Carnevali, Matteo Ghilli, Caterina Vivanet, Chiara Guglielmi, Laura Cortesi, Brunella Pilato, Margherita Patruno, Maria A. Caligo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7693, p 7693 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences
Volume 22
Issue 14
With the progress of sequencing technologies, an ever-increasing number of variants of unknown functional and clinical significance (VUS) have been identified in both coding and non-coding regions of the main Breast Cancer (BC) predisposition genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403c72eb2f79369f6234a7eb40fee995
https://doi.org/10.3390/ijms22147693
https://doi.org/10.3390/ijms22147693
Autor:
Maria A. Caligo, Abdellatif Benider, Amal Tazzite, Sellama Nadifi, Elisabetta Falaschi, Hassan Jouhadi, Anita Collavoli, Paolo Aretini
Publikováno v:
Gynecologic Oncology. 125:687-692
Objective Breast cancer is the most common female cancer in Morocco. About 5 to 10% are due to hereditary predisposition and mutations in BRCA1 and BRCA2 genes are responsible for an important proportion of high-risk breast/ovarian cancer families. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf620f51fe9dd525c45556c600c3b890
https://doi.org/10.1016/j.ygyno.2012.03.007
https://doi.org/10.1016/j.ygyno.2012.03.007
Autor:
E. Rossetti, Elisabetta Falaschi, Maria A. Caligo, Luisa Maresca, Anita Collavoli, Mariella Tancredi, Paolo Aretini, Cristina Cozzani, Alvaro Galli, Antonio Giuseppe Naccarato, Samuele Lodovichi, Laura Spugnesi, Tiziana Cervelli
Publikováno v:
European journal of medical genetics. 58(10)
BRCA1 interacts with several proteins implicated in homologous and non homologous recombination and in mismatch repair. The aim of this study is to determine if MSH2, a well known partner of BRCA1 involved in DNA repair, may contribute to breast and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4662bea62d88e4b7e89bafae43edd5dd
https://pubmed.ncbi.nlm.nih.gov/26381082
https://pubmed.ncbi.nlm.nih.gov/26381082
Publikováno v:
International Journal of Molecular Medicine
The study of BRCA1 and BRCA2 genes and their alterations has been essential to the understanding of the development of familial breast and ovarian cancers. Many of the variants identified have an unknown pathogenic significance. These include variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e77c3c0ed3c288bb46cd8ffb08c3ba5
http://hdl.handle.net/11568/705263
http://hdl.handle.net/11568/705263
Autor:
Elisa Sensi, Generoso Bevilacqua, G Cipollini, Paolo Aretini, Grazia Lombardi, Maria A. Caligo, Fabrizia Bonatti, Mariella Tancredi, Chiara Pepe, Elisabetta Falaschi
Publikováno v:
Cancer Genetics and Cytogenetics. 170:93-101
Alterations in BRCA1 and BRCA2 genes account for a large proportion of hereditary breast and ovarian cancers. Mutations and variants of unknown pathological significance have been identified in both genes; however, most of them have been studied only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76931208b18acb9cb8cf1eb2d89d97b8
https://doi.org/10.1016/j.cancergencyto.2006.05.005
https://doi.org/10.1016/j.cancergencyto.2006.05.005
Autor:
Elisabetta Falaschi, Anita Collavoli, Cristina Balia, Laura Spugnesi, Maria A. Caligo, Valentina Quercioli, Alvaro Galli
Publikováno v:
Mutagenesis. 28(2)
The tumour-suppressor gene BRCA2 has been demonstrated to be involved in maintenance of genome integrity by affecting DNA double-strand break repair and homologous recombination. Protein-truncating mutations in BRCA2 predispose women to early onset b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f21635335b37b081f7c7ec9d6655556
https://pubmed.ncbi.nlm.nih.gov/23328489
https://pubmed.ncbi.nlm.nih.gov/23328489
Autor:
Generoso Bevilacqua, Grazia Lombardi, Paolo Aretini, Claudio Di Cristofano, Maria A. Caligo, Elisa Sensi, Elisabetta Falaschi, Antonio Giuseppe Naccarato, Manuela Roncella
Publikováno v:
Genes, chromosomescancer. 46(9)
BARD1 (BRCA1-associated RING domain) is the dominant binding partner of BRCA1 in vivo. The BARD1 gene has been reported to be mutated in a subset of breast and ovarian cancer patients and BARD1 germ-line mutations have been identified in breast cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bc6bf8e66a31820a1f99fe77e05a08
https://pubmed.ncbi.nlm.nih.gov/17497650
https://pubmed.ncbi.nlm.nih.gov/17497650