Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elisabetta Di Nicola"'
Autor:
Paola Sanese, Katia De Marco, Martina Lepore Signorile, Francesca La Rocca, Giovanna Forte, Marialaura Latrofa, Candida Fasano, Vittoria Disciglio, Elisabetta Di Nicola, Antonino Pantaleo, Giusy Bianco, Vito Spilotro, Claudia Ferroni, Matilde Tubertini, Nicoletta Labarile, Lucia De Marinis, Raffaele Armentano, Gianluigi Gigante, Valerio Lantone, Giuliano Lantone, Marina Naldi, Manuela Bartolini, Greta Varchi, Alberto Del Rio, Valentina Grossi, Cristiano Simone
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background SMYD3 has been found implicated in cancer progression. Its overexpression correlates with cancer growth and invasion, especially in gastrointestinal tumors. SMYD3 transactivates multiple oncogenic mechanisms, favoring cancer devel
Externí odkaz:
https://doaj.org/article/8a2633f1acb94d078dc7358f99a7585f
Autor:
Martina Lepore Signorile, Candida Fasano, Giovanna Forte, Katia De Marco, Paola Sanese, Vittoria Disciglio, Elisabetta Di Nicola, Antonino Pantaleo, Cristiano Simone, Valentina Grossi
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Background Activation of the Wnt pathway has been linked to colorectal cancer (CRC). Previous reports suggest that Wnt3a can activate p38. Besides, p38α feeds into the canonical Wnt/β-catenin pathway by inhibiting GSK3β through phosphoryl
Externí odkaz:
https://doaj.org/article/b1012b50cb79450496cd287a38de5e67
Autor:
Candida Fasano, Martina Lepore Signorile, Elisabetta Di Nicola, Antonino Pantaleo, Giovanna Forte, Katia De Marco, Paola Sanese, Vittoria Disciglio, Valentina Grossi, Cristiano Simone
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5240-5248 (2023)
SMDY3 is a histone-lysine N-methyltransferase involved in several oncogenic processes and is believed to play a major role in various cancer hallmarks. Recently, we identified ATM, BRCA2, CHK2, MTOR, BLM, MET, AMPK, and p130 as direct SMYD3 interacto
Externí odkaz:
https://doaj.org/article/bd4d1a6d0f7846eab0639bd64810a285
Autor:
Martina Lepore Signorile, Paola Sanese, Elisabetta Di Nicola, Candida Fasano, Giovanna Forte, Katia De Marco, Vittoria Disciglio, Marialaura Latrofa, Antonino Pantaleo, Greta Varchi, Alberto Del Rio, Valentina Grossi, Cristiano Simone
Publikováno v:
Cells, Vol 12, Iss 22, p 2644 (2023)
Cells respond to DNA damage by activating a complex array of signaling networks, which include the AMPK and mTOR pathways. After DNA double-strand breakage, ATM, a core component of the DNA repair system, activates the AMPK-TSC2 pathway, leading to t
Externí odkaz:
https://doaj.org/article/eb58c6ed5d344b02b7d82cc1486973d8
Autor:
Katia De Marco, Martina Lepore Signorile, Elisabetta Di Nicola, Paola Sanese, Candida Fasano, Giovanna Forte, Vittoria Disciglio, Antonino Pantaleo, Greta Varchi, Alberto Del Rio, Valentina Grossi, Cristiano Simone
Publikováno v:
Cells, Vol 12, Iss 20, p 2481 (2023)
Gastric cancer (GC) is the third most deadly cancer worldwide. Considerable efforts have been made to find targetable drivers in order to improve patient outcomes. MET is one of the most important factors involved in GC initiation and progression as
Externí odkaz:
https://doaj.org/article/dc3787f7fa7c41778954421e09c2f045