Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Elisabetta Daré"'
Autor:
Christopher J. Barker, Sung Ho Ryu, Per Olof Berggren, Jaeyoon Kim, Subu Surendran Rajasekaran, Elisabetta Daré
Publikováno v:
Cellular Signalling. 58:131-136
The inositol pyrophosphate, diphosphoinositol pentakisphosphate (IP7), is thought to negatively regulate the critical insulin signaling protein Akt/PKB. Knockdown of the IP7-generating inositol hexakisphosphate kinase 1 (IP6K1) results in a concomita
Autor:
Rafael Simas, Martin Köhler, Subu Surendran Rajasekaran, Thais Soprani Ayala, Joilson O. Martins, Sabrina de Souza Ferreira, Elisabetta Daré, Fernando Henrique Galvão Tessaro, Per Olof Berggren, Christopher J. Barker
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Diabetes
Universidade de São Paulo (USP)
instacron:USP
Diabetes
Glucose-stimulated insulin secretion is the hallmark of the pancreatic β-cell, a critical player in the regulation of blood glucose concentration. In 1974, the remarkable observation was made that an efflux of intracellular inorganic phosphate (Pi)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e594c65c48bbeee55fa4d4f80b28191d
Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells
Autor:
Ingo B. Leibiger, Martin Köhler, Tilo Moede, Elisabetta Daré, Thusitha P. Muhandiramlage, Barbara Leibiger, Pilar Vaca Sanchez, Per Olof Berggren
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
The secretion of glucagon by pancreatic alpha cells is regulated by a number of external and intrinsic factors. While the electrophysiological processes linking a lowering of glucose concentrations to an increased glucagon release are well characteri
Autor:
Robin Fröbom, Robert Bränström, Rui M. M. Branca, Weng-Onn Lui, Janne Lehtiö, Lukas M. Orre, Jan Zedenius, Pinar Akcakaya, Erik Berglund, Jaeyoon Kim, Per Olof Berggren, Catharina Larsson, Elisabetta Daré
Publikováno v:
Experimental Cell Research. 336:158-170
Strategies for correct diagnosis, treatment evaluation and recurrence prediction are important for the prognosis and mortality rates among cancer patients. In spite of major improvements in clinical management, gastrointestinal stromal tumors (GISTs)
Autor:
Christopher Illies, Subu Surendran Rajasekaran, Jesper Gromada, Gian-Carlo Gaboardi, Sung Ho Ryu, Martin Köhler, Stephen B. Shears, Joilson O. Martins, Sabrina de Souza Ferreira, Eduardo Lima Nolasco, Karen Tiago dos Santos, Jaeyoon Kim, Elisabetta Daré, Per Olof Berggren, Chunfang Gu, Christopher J. Barker
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cellular Signalling
Universidade de São Paulo (USP)
instacron:USP
Cellular Signalling
Diphosphoinositol pentakisphosphate (IP7) is critical for the exocytotic capacity of the pancreatic β-cell, but its regulation by the primary instigator of β-cell exocytosis, glucose, is unknown. The high Km for ATP of the IP7-generating enzymes, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc78a2d533598d7f2293e8e591adc027
Autor:
Subu Surendran, Rajasekaran, Christopher, Illies, Stephen B, Shears, Huanchen, Wang, Thais S, Ayala, Joilson O, Martins, Elisabetta, Daré, Per-Olof, Berggren, Christopher J, Barker
Publikováno v:
Cellular Signalling
Inositol pyrophosphates have emerged as important regulators of many critical cellular processes from vesicle trafficking and cytoskeletal rearrangement to telomere length regulation and apoptosis. We have previously demonstrated that 5-di-phosphoino
Autor:
Gunnar Schulte, Guro Valen, Fred Haugen, Bertil B. Fredholm, Cecilia Lövdahl, Elisabetta Daré, Jiangning Yang, Xiaowei Zheng
Publikováno v:
Acta Physiologica. 210:590-599
Aim In inflamed and damaged cardiovascular tissues, local extracellular adenosine concentrations increase coincidentally with activation of the transcription factor nuclear factor kappa B (NFκB). To investigate whether adenosine influences NFκB act
Autor:
Martin Köhler, Catharina Larsson, Weng-Onn Lui, Elisabetta Daré, Pinar Akcakaya, Craig A. Aspinwall, Erik Berglund, Robert Bränström, Jan Zedenius, Per Olof Berggren, David Berglund, Mehran Ghaderi
Publikováno v:
Experimental Cell Research. 319:1229-1238
Gastrointestinal stromal tumors (GISTs) are thought to originate from the electrically active pacemaker cells of the gastrointestinal tract. Despite the presence of synaptic-like vesicles and proteins involved in cell secretion it remains unclear whe
Autor:
Sabrina de Souza Ferreira, Eduardo Lima Nolasco, Joilson O. Martins, Christopher J. Barker, Chunfang Gu, Christopher Illies, Elisabetta Daré, Jaeyoon Kim, Gian-Carlo Gaboardi, Subu Surendran Rajasekaran, Karen Tiago dos Santos, Martin Köhler, Sung Ho Ryu, Per Olof Berggren, Jesper Gromada, Stephen B. Shears
Publikováno v:
Cellular Signalling. 53:415
Publikováno v:
Chemico-Biological Interactions. 188:301-308
Methylmercury is a widely distributed environmental toxicant with detrimental effects on the developing and adult nervous system. Due to its accumulation in the food chain, chronic exposure to methylmercury via consumption of fish and sea mammals is