Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Elisabetta, Zulato"'
Autor:
Andrea Boscolo Bragadin, Paola Del Bianco, Elisabetta Zulato, Ilaria Attili, Alberto Pavan, Jessica Carlet, Ludovica Marra, Valentina Guarneri, Stefano Indraccolo, Laura Bonanno
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract High heterogeneity in clinical benefit characterizes the use of immune checkpoint inhibitors (ICIs) in non-small cell lung cancer (NSCLC). We prospectively enrolled 113 advanced NSCLC patients treated with ICIs and performed liquid biopsy at
Externí odkaz:
https://doaj.org/article/4bf7c8c91ecc4b6c9e8e3e50728b08c1
Autor:
Valeria Tosello, Angela Grassi, Dominic Rose, Loc Carlo Bao, Elisabetta Zulato, Chiara Dalle Fratte, Maurizio Polano, Paola Del Bianco, Giulia Pasello, Valentina Guarneri, Stefano Indraccolo, Laura Bonanno
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Liquid biopsy has recently emerged as an important tool in clinical practice particularly for lung cancer patients. We retrospectively evaluated cell-free DNA analyses performed at our Institution by next generation sequencing methodology de
Externí odkaz:
https://doaj.org/article/aafccb68c79c428c82556566c94013f3
Autor:
Francesco Pepe, Gianluca Russo, Alessandro Venuta, Claudia Scimone, Mariantonia Nacchio, Pasquale Pisapia, Gaia Goteri, Francesca Barbisan, Caterina Chiappetta, Angelina Pernazza, Domenico Campagna, Marco Giordano, Giuseppe Perrone, Giovanna Sabarese, Annalisa Altimari, Dario de Biase, Giovanni Tallini, Daniele Calistri, Elisa Chiadini, Laura Capelli, Alfredo Santinelli, Anna Elisa Gulini, Elisa Pierpaoli, Manuela Badiali, Stefania Murru, Riccardo Murgia, Elena Guerini Rocco, Konstantinos Venetis, Nicola Fusco, Denise Morotti, Andrea Gianatti, Daniela Furlan, Giulio Rossi, Laura Melocchi, Maria Russo, Caterina De Luca, Lucia Palumbo, Saverio Simonelli, Antonella Maffè, Paola Francia di Celle, Tiziana Venesio, Maria Scatolini, Enrico Grosso, Sara Orecchia, Matteo Fassan, Mariangela Balistreri, Elisabetta Zulato, Daniela Reghellin, Elena Lazzari, Maria Santacatterina, Maria Liliana Piredda, Manuela Riccardi, Licia Laurino, Elena Roz, Domenico Longo, Daniela Petronilla Romeo, Carmine Fazzari, Andrea Moreno-Manuel, Giuseppe Diego Puglia, Andrey D. Prjibelski, Daria Shafranskaya, Luisella Righi, Angela Listì, Domenico Vitale, Antonino Iaccarino, Umberto Malapelle, Giancarlo Troncone
Publikováno v:
Oncology and Therapy, Vol 12, Iss 1, Pp 73-95 (2024)
Abstract Introduction Biomarker testing is mandatory for the clinical management of patients with advanced non-small cell lung cancer (NSCLC). Myriads of technical platforms are now available for biomarker analysis with differences in terms of multip
Externí odkaz:
https://doaj.org/article/a35808bcabd148c5a14f08b4834ff7fc
Autor:
Federica Ferrarini, Elisabetta Zulato, Massimo Moro, Paola Del Bianco, Cristina Borzi, Giovanni Esposito, Tiziana Zanin, Gabriella Sozzi, Stefano Indraccolo
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionGenetically characterized patient-derived tumor xenografts (PDX) are a valuable resource to understand the biological complexity of cancer and to investigate new therapeutic approaches. Previous studies, however, lack information about me
Externí odkaz:
https://doaj.org/article/dcca2b4f92c84f669ae1e5232bb5ec17
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Kirsten rat sarcoma viral oncogene homolog (KRAS) gene encodes a GTPase that acts as a molecular switch for intracellular signal transduction, promoting cell growth and proliferation. Mutations in the KRAS gene represent important biomarkers for NSCL
Externí odkaz:
https://doaj.org/article/990406d02913462792d874c62137a1db
Autor:
Loredana Urso, Grazia Vernaci, Jessica Carlet, Marcello Lo Mele, Matteo Fassan, Elisabetta Zulato, Giovanni Faggioni, Alice Menichetti, Elisabetta Di Liso, Gaia Griguolo, Cristina Falci, Pierfranco Conte, Stefano Indraccolo, Valentina Guarneri, Maria Vittoria Dieci
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Endocrine therapy represents the cornerstone of treatment in hormone receptor-positive (HR+), HER2-negative metastatic breast cancer (mBC). The natural course of this disease is marked by endocrine resistance, mainly due to Estrogen Receptor 1 (ESR1)
Externí odkaz:
https://doaj.org/article/28efcefbd228445b884d856109889621
Autor:
Giorgia Nardo, Jessica Carlet, Ludovica Marra, Laura Bonanno, Alice Boscolo, Alessandro Dal Maso, Andrea Boscolo Bragadin, Stefano Indraccolo, Elisabetta Zulato
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundMolecular profiling of advanced EGFR mutated NSCLC has recently demonstrated the co-existence of multiple genetic alterations. Specifically, co-existing KRAS-mutations in EGFR NSCLCs have been described, despite their prevalence at progress
Externí odkaz:
https://doaj.org/article/9a42db7d016b40d6898c73b7ab6b5fc6
Autor:
Ilaria Piga, Martina Verza, Francesca Montenegro, Giorgia Nardo, Elisabetta Zulato, Tiziana Zanin, Paola Del Bianco, Giovanni Esposito, Stefano Indraccolo
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Metabolic profiling of cancer is a rising interest in the field of biomarker development. One bottleneck of its clinical exploitation, however, is the lack of simple and quantitative techniques that enable to capture the key metabolic traits of tumor
Externí odkaz:
https://doaj.org/article/ab3953097d8b4812b78e1c5823dacdb4
Autor:
Elisabetta Zulato, Paola Del Bianco, Giorgia Nardo, Ilaria Attili, Alberto Pavan, Andrea Boscolo Bragadin, Ludovica Marra, Giulia Pasello, Matteo Fassan, Fiorella Calabrese, Valentina Guarneri, Pier Franco Conte, Stefano Indraccolo, Laura Bonanno
Publikováno v:
British Journal of Cancer. 127:2034-2042
Background Immune checkpoint inhibitors (ICIs) have revolutionised treatment of advanced non-small cell lung cancer (aNSCLC), but a proportion of patients had no clinical benefit and even experienced detrimental effects. This study aims to characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd84353759c062c8e21e11dc3b696a8d
https://doi.org/10.1038/s41416-022-01978-1
https://doi.org/10.1038/s41416-022-01978-1
Autor:
Elisabetta Zulato, Valeria Tosello, Giorgia Nardo, Laura Bonanno, Paola Del Bianco, Stefano Indraccolo
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1468 (2021)
Genetic screening of somatic mutations in circulating free DNA (cfDNA) opens up new opportunities for personalized medicine. In this study, we aim to illustrate the implementation of NGS-based liquid biopsy in clinical practice for the detection of s
Externí odkaz:
https://doaj.org/article/4353591550dd4e6e9dcb74516e25cd88