Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elisabetta, Cribioli"'
Autor:
Sebastian Martin, Lennard Wendlinger, Béatrice Zitti, Mehdi Hicham, Viktoriia Postupalenko, Léo Marx, Greta Giordano-Attianese, Elisabetta Cribioli, Melita Irving, Alexandra Litvinenko, Radmila Faizova, David Viertl, Margret Schottelius
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Purpose CXCR3 is expressed on activated T cells and plays a crucial role in T-cell recruitment to the tumor microenvironment (TME) during cell-based and immune checkpoint inhibitor (ICI) immunotherapy. This study utilized a 64Cu-labeled NOTA
Externí odkaz:
https://doaj.org/article/1fa926ec6f094b7f9c14f3e6b53020da
Autor:
Elisabetta Cribioli, Greta Maria Paola Giordano Attianese, Pierpaolo Ginefra, Amandine Signorino-Gelo, Romain Vuillefroy de Silly, Nicola Vannini, Christoph Hess, Melita Irving, George Coukos
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the tremendous success of adoptive T-cell therapies (ACT) in fighting certain hematologic malignancies, not all patients respond, a proportion experience relapse, and effective ACT of most solid tumors remains elusive. In order to improve res
Externí odkaz:
https://doaj.org/article/4281944bf7cc4a21b14d4315acba88d6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chimeric antigen receptor (CAR) T cells have emerged as a powerful immunotherapeutic tool against certain hematological malignancies but a significant proportion of patients either do not respond or they relapse, sometimes as a result of target antig
Externí odkaz:
https://doaj.org/article/1458ec2a587246de8605c5bfca12e1ec
Autor:
George Coukos, Evripidis Lanitis, Melita Irving, Paris Kosti, Catherine Ronet, Elisabetta Cribioli, Giorgia Rota, Aodrenn Spill, Patrick Reichenbach, Vincent Zoete, Denarda Dangaj Laniti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background The adoptive transfer of chimeric antigen receptor (CAR)-T cells has emerged as a potent immunotherapy against some hematological malignancies but not yet for epithelial-derived solid tumors. One critical issue is the paucity of broadly ex
Externí odkaz:
https://doaj.org/article/00de700490344b409b7db715eb77e9ab
Autor:
Yaquelin Ortiz-Miranda, Maria Masid, Cristina Jiménez-Luna, Galia Magela Montalvo Bereau, Tania Muller, Nicolas Rayroux, Elisabetta Cribioli, Jesús Corría-Osorio, Helen Carrasco Hope, Romain Vuillefroy de Silly, Bili Seijo, Pierpaolo Ginefra, Kalet León, Nicola Vannini, Ping-Chih Ho, Isaac Crespo, Vassily Hatzimanikatis, Melita Irving, George Coukos
SummaryInterleukin-2 receptor (IL-2R)-mediated intracellular signaling is a key regulator of T-cell fate decisions. While the potent signals generated by IL-2 engagement execute effector differentiation, elevated metabolic activities and rapid cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54cc544864cfa0ccfa381ec77d49301
https://doi.org/10.1101/2023.05.24.541283
https://doi.org/10.1101/2023.05.24.541283
Autor:
Jonas, Lötscher, Adrià-Arnau, Martí I Líndez, Nicole, Kirchhammer, Elisabetta, Cribioli, Greta Maria Paola, Giordano Attianese, Marcel P, Trefny, Markus, Lenz, Sacha I, Rothschild, Paolo, Strati, Marco, Künzli, Claudia, Lotter, Susanne H, Schenk, Philippe, Dehio, Jordan, Löliger, Ludivine, Litzler, David, Schreiner, Victoria, Koch, Nicolas, Page, Dahye, Lee, Jasmin, Grählert, Dmitry, Kuzmin, Anne-Valérie, Burgener, Doron, Merkler, Miklos, Pless, Maria L, Balmer, Walter, Reith, Jörg, Huwyler, Melita, Irving, Carolyn G, King, Alfred, Zippelius, Christoph, Hess
Publikováno v:
Cell. 185(4)
The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6cfb6d8cca3f0ddb2bc7221e4f0bfe8
https://pubmed.ncbi.nlm.nih.gov/35260350
https://pubmed.ncbi.nlm.nih.gov/35260350
Autor:
Jonas Lötscher, Adrià-Arnau Martí i Líndez, Nicole Kirchhammer, Elisabetta Cribioli, Greta Maria Paola Giordano Attianese, Marcel P. Trefny, Markus Lenz, Sacha I. Rothschild, Paolo Strati, Marco Künzli, Claudia Lotter, Susanne H. Schenk, Philippe Dehio, Jordan Löliger, Ludivine Litzler, David Schreiner, Victoria Koch, Nicolas Page, Dahye Lee, Jasmin Grählert, Dmitry Kuzmin, Anne-Valérie Burgener, Doron Merkler, Miklos Pless, Maria L. Balmer, Walter Reith, Jörg Huwyler, Melita Irving, Carolyn G. King, Alfred Zippelius, Christoph Hess
Publikováno v:
Cell. 185:585-602.e29
The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8+ T��cells, thereby augmenting calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aac832ab7bc74750040c9812d41abd
https://doi.org/10.1016/j.cell.2021.12.039
https://doi.org/10.1016/j.cell.2021.12.039
Autor:
Aodrenn Spill, Giorgia Rota, George Coukos, Vincent Zoete, Denarda Dangaj Laniti, Catherine Ronet, Melita Irving, Paris Kosti, Patrick Reichenbach, Evripidis Lanitis, Elisabetta Cribioli
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundThe adoptive transfer of chimeric antigen receptor (CAR)-T cells has emerged as a potent immunotherapy against some hematological malignancies but not yet for epithelial-derived solid tumors. One critical issue is the paucity of broadly exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e19e79a1d07104a373c258551b711d
https://doi.org/10.1136/jitc-2020-002151
https://doi.org/10.1136/jitc-2020-002151
Autor:
Melita Irving, Jaume Bonet, Elise Gray-Gaillard, Patrick Reichenbach, Byung-Ha Oh, George Coukos, Sailan Shui, Angel De Jesus Corria Osorio, Mi Jeong Kwak, Sabrina Vollers, Bruno E. Correia, Pablo Gainza, Greta Giordano-Attianese, Elisabetta Cribioli, Seong Hoon Kim
Publikováno v:
Nature Biotechnology. 38:503-503
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32dcbfcf35e547f944e0132f8f3ede96
https://doi.org/10.1038/s41587-020-0461-z
https://doi.org/10.1038/s41587-020-0461-z
Autor:
Virna Marin, Sarah Tettamanti, Ettore Biagi, Irene Pizzitola, Martin Pule, Andrea Biondi, Elisabetta Cribioli, Brian Philip
Publikováno v:
Human Gene Therapy Methods. 23:376-386
Use of adoptive T-cell therapy (ACT) is increasing; however, T-cell therapy can result in severe toxicity. Consequently, several suicide-gene strategies that allow selective destruction of the infused T cells have been described. We compared effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c299b0ae68f660e4355d5882acee44e4
https://doi.org/10.1089/hgtb.2012.050
https://doi.org/10.1089/hgtb.2012.050