Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Elisabetta, Cerbai"'
Autor:
Lorenzo Santini, Claudia Duranti, Chiara Palandri, Lucrezia Giammarino, Monica Musumeci, Lucia Carlucci, Chiara Capitani, Rossella Colasurdo, Fabio Recchia, Elisabetta Cerbai, Raffaele Coppini, Annarosa Arcangeli
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: In the last decades, mounting evidence has pointed out the human ether-á-go-go–related gene (hERG1) potassium channel as a novel biomarker in human cancers. However, hERG1 sustains the cardiac repolarizing current IKr and its blockad
Externí odkaz:
https://doaj.org/article/3944c718452b406297dcf82774f7ecd5
Autor:
Sara Landini, Lucilla Gatt, Albina Candian, Simona Viciani, Emilia Giusti, Caterina Mugelli, Valentina Lunesu, Federica Gattillo, Elisabetta Cerbai
Publikováno v:
European Journal of Privacy Law & Technologies, Iss 1, Pp 34-44 (2023)
Organoids, briefly and simply stated, are miniature replicas of human organs and tissues: they derive from induced pluripotent stem cells (iPSC) or from adult cells and tissues, including tumors. They represent an important tool for personalized medi
Externí odkaz:
https://doaj.org/article/769d28aaf1ff4fd8bb46745fc65677dc
Autor:
Josè Manuel Pioner, Lorenzo Santini, Chiara Palandri, Marianna Langione, Bruno Grandinetti, Silvia Querceto, Daniele Martella, Costanza Mazzantini, Beatrice Scellini, Lucrezia Giammarino, Flavia Lupi, Francesco Mazzarotto, Aoife Gowran, Davide Rovina, Rosaria Santoro, Giulio Pompilio, Chiara Tesi, Camilla Parmeggiani, Michael Regnier, Elisabetta Cerbai, David L. Mack, Corrado Poggesi, Cecilia Ferrantini, Raffaele Coppini
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/09df826ed4e8452db5de3039b389a56f
Autor:
Francesca Girolami, Valentina Spinelli, Niccolò Maurizi, Martina Focardi, Gabriella Nesi, Vincenza Maio, Rossella Grifoni, Giuseppe Albora, Bruno Bertaccini, Mattia Targetti, Raffaele Coppini, Silvia Favilli, Iacopo Olivotto, Elisabetta Cerbai
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundSudden cardiac arrest (SCA) in young people represents a dramatic event, often leading to severe neurologic outcomes or sudden cardiac death (SCD), and is frequently caused by genetic heart diseases. In this study, we report the results of
Externí odkaz:
https://doaj.org/article/64d289ff018f4d088387e608eb3b9777
Autor:
Josè Manuel Pioner, Lorenzo Santini, Chiara Palandri, Marianna Langione, Bruno Grandinetti, Silvia Querceto, Daniele Martella, Costanza Mazzantini, Beatrice Scellini, Lucrezia Giammarino, Flavia Lupi, Francesco Mazzarotto, Aoife Gowran, Davide Rovina, Rosaria Santoro, Giulio Pompilio, Chiara Tesi, Camilla Parmeggiani, Michael Regnier, Elisabetta Cerbai, David L. Mack, Corrado Poggesi, Cecilia Ferrantini, Raffaele Coppini
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cardiomyocytes differentiated from human induced Pluripotent Stem Cells (hiPSC- CMs) are a unique source for modelling inherited cardiomyopathies. In particular, the possibility of observing maturation processes in a simple culture dish opens novel p
Externí odkaz:
https://doaj.org/article/95e6e0e9e12446fa8397f9dbba59be9f
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Pirfenidone is a small drug with marked antifibrotic activity approved for the treatment of Idiopathic pulmonary fibrosis. Recently, its peculiar pharmacological profile has attracted attention for its potential therapeutic benefit for extra-pulmonar
Externí odkaz:
https://doaj.org/article/2dcfa912f9784c0394e8346846c1063e
Autor:
Alessia Argirò, Carolyn Ho, Sharlene M. Day, Jolanda van der Velden, Elisabetta Cerbai, Sara Saberi, Jil C. Tardiff, Neal K. Lakdawala, Iacopo Olivotto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 9 (2022)
Cardiomyopathies are a heterogeneous collection of diseases that have in common primary functional and structural abnormalities of the heart muscle, often genetically determined. The most effective categorization of cardiomyopathies is based on the p
Externí odkaz:
https://doaj.org/article/f96e6077fb684b2a939552ca9ab2ed06
Autor:
Josè Manuel Pioner, Giulia Vitale, Francesca Gentile, Beatrice Scellini, Nicoletta Piroddi, Elisabetta Cerbai, Iacopo Olivotto, Jil Tardiff, Raffaele Coppini, Chiara Tesi, Corrado Poggesi, Cecilia Ferrantini
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Atrial dilation and atrial fibrillation (AF) are common in Hypertrophic CardioMyopathy (HCM) patients and associated with a worsening of prognosis. The pathogenesis of atrial myopathy in HCM remains poorly investigated and no specific association wit
Externí odkaz:
https://doaj.org/article/06e829932fea48f2bca1c796e4de4f36
Autor:
Caterina Credi, Valentina Balducci, U. Munagala, C. Cianca, S. Bigiarini, Antoine A. F. de Vries, Leslie M. Loew, Francesco S. Pavone, Elisabetta Cerbai, Laura Sartiani, Leonardo Sacconi
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Current techniques for fast characterization of cardiac electrophysiology employ optical technologies to control and monitor action potential features of single cells or cellular monolayers placed in multiwell plates. High-speed investigation capacit
Externí odkaz:
https://doaj.org/article/66e7aad5fe1847fba615e6cf481cae50
Autor:
Raffaele Coppini, MD, PhD, Cecilia Ferrantini, MD, PhD, Josè Manuel Pioner, PhD, Lorenzo Santini, MS, Zhinuo J. Wang, PhD, Chiara Palandri, MS, Marina Scardigli, PhD, Giulia Vitale, MS, Leonardo Sacconi, PhD, Pierluigi Stefàno, MD, Laura Flink, MD, Katherine Riedy, MD, Francesco Saverio Pavone, PhD, Elisabetta Cerbai, PhD, Corrado Poggesi, MD, Alessandro Mugelli, MD, Alfonso Bueno-Orovio, PhD, Iacopo Olivotto, MD, Mark V. Sherrid, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 795-813 (2019)
Summary: Disopyramide is effective and safe in patients with obstructive hypertrophic cardiomyopathy. However, its cellular and molecular mechanisms of action are unknown. We tested disopyramide in cardiomyocytes from the septum of surgical myectomy
Externí odkaz:
https://doaj.org/article/383410aaa4f04130b18b186ad5f7d1d6