Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elisabeth von der Mark"'
Autor:
Gregor Dernick, Stefan Obermüller, Cyrill Mangold, Christine Magg, Hugues Matile, Oliver Gutmann, Elisabeth von der Mark, Corinne Handschin, Cyrille Maugeais, Eric J. Niesor
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2323-2331 (2011)
The composition of lipoproteins and the association of proteins with various particles are of much interest in the context of cardiovascular disease. Here, we describe a technique for the multidimensional analysis of lipoproteins and their associated
Externí odkaz:
https://doaj.org/article/9ea5e0c950cc4b3fa52bc98aea6f6e17
Autor:
Eric J. Niesor, Christine Magg, Naoto Ogawa, Hiroshi Okamoto, Elisabeth von der Mark, Hugues Matile, Georg Schmid, Roger G. Clerc, Evelyne Chaput, Denise Blum-Kaelin, Walter Huber, Ralf Thoma, Philippe Pflieger, Makoto Kakutani, Daisuke Takahashi, Gregor Dernick, Cyrille Maugeais
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3443-3454 (2010)
The mechanism by which cholesteryl ester transfer protein (CETP) activity affects HDL metabolism was investigated using agents that selectively target CETP (dalcetrapib, torcetrapib, anacetrapib). In contrast with torcetrapib and anacetrapib, dalcetr
Externí odkaz:
https://doaj.org/article/6b0ce888f3634531a2b4ff3ba44e3457
Autor:
Henrietta Dehmlow, Ralf Thoma, Armin Ruf, Narendra Panday, Elisabeth Von Der Mark, Olivier Morand, Hans Peter Märki, Manfred Kansy, Peter Hartman, Philippe Coassolo, Alexander Chucholowski, Denise Blum-Kaelin, Johannes Aebi, Jean Ackermann, Tanja Schulz-Gasch
Publikováno v:
CHIMIA, Vol 59, Iss 3 (2005)
Novel inhibitors of oxidosqualene cyclase (OSC) for the treatment of dyslipidemia are reported. Starting point for the chemistry program was a set of compounds derived from a fungicide project which, in addition to high affinity for OSC from Candida
Externí odkaz:
https://doaj.org/article/52a208c1b0c345b49b3846af115d21f8
Autor:
Cyrille Maugeais, Philippe Pflieger, Elisabeth von der Mark, Anne Perez, Christine Magg, Eric J. Niesor
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:1644-1650
Cholesteryl ester transfer protein (CETP), a key regulator of high-density lipoprotein (HDL) metabolism, induces HDL remodeling by transferring lipids between apolipoprotein B-containing lipoproteins and HDL, and/or by promoting lipid transfer betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4338cec272f3e8ad8a00f9ebca8e2f9b
https://doi.org/10.1016/j.bbalip.2013.07.007
https://doi.org/10.1016/j.bbalip.2013.07.007
Autor:
Elisabeth von der Mark, Stefan Obermüller, Cyrille Maugeais, Gregor Dernick, Oliver Gutmann, Christine Magg, Hugues Matile, Eric J. Niesor, Corinne Handschin, Cyrill Mangold
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2323-2331 (2011)
The composition of lipoproteins and the association of proteins with various particles are of much interest in the context of cardiovascular disease. Here, we describe a technique for the multidimensional analysis of lipoproteins and their associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31cae501b80dea4ad969b2c69dc5148
http://www.sciencedirect.com/science/article/pii/S0022227520408375
http://www.sciencedirect.com/science/article/pii/S0022227520408375
Autor:
Brigitte D'Arcy, Gregor Dernick, Elisabeth von der Mark, Ralf Thoma, Matthias E. Lauer, Henning Stahlberg, Cyrille Maugeais, Shirley A. Müller, Eric J. Niesor, Christine Magg, Alexandra Graff-Meyer, Michael Hennig, Hugues Matile, Sebastian Scherer, Philippe Ringler, Arne C. Rufer
Publikováno v:
Journal of structural biology
The cholesteryl ester transfer protein (CETP) enables the transfer of cholesteryl ester (CE) from high density lipoproteins (HDL) to low-density lipoproteins (LDL) in the plasma compartment. CETP inhibition raises plasma levels of HDL cholesterol; a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0baab81955b89667927e6256d2f641
https://pubmed.ncbi.nlm.nih.gov/26876146
https://pubmed.ncbi.nlm.nih.gov/26876146
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Introduction: Inhibition of the cholesteryl ester transfer between HDL and apoB-containing lipoproteins by dalcetrapib requires cysteine 13 (C13) of CETP. In contrast to the CETP inhibitors torcetrapib or anacetrapib, the CETP modulator dalcetrapib s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7147c1a308a7a46c4393fd47299110d0
https://doi.org/10.1161/atvb.32.suppl_1.a69
https://doi.org/10.1161/atvb.32.suppl_1.a69
Autor:
Patrizia Tarugi, Maurizio Averna, Peter M. Nilsson, Gregor Dernick, Elisabeth von der Mark, Angelo B. Cefalù, Eric J. Niesor, Laura Calabresi
Hyperalphalipoproteinemia, as observed in patients who are either homozygous or heterozygous for cholesteryl ester transfer protein (CETP) deficiency, has been shown to be associated with striking changes in apolipoprotein size distribution, namely,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5245521d5bb905f151e9482c826ab75
http://hdl.handle.net/10447/74505
http://hdl.handle.net/10447/74505
Autor:
Gregor Dernick, Christine Magg, Walter Huber, Ralf Thoma, Cyrille Maugeais, Eric J. Niesor, Elisabeth von der Mark, Georg Schmid
Publikováno v:
Biophysical Journal. 98(3)
Cholesteryl ester transfer protein (CETP) is a hydrophobic glycoprotein in plasma and facilitates the exchange of neutral lipids between various lipoproteins resulting in a net transport of cholesteryl ester from HDL to LDL. Decrease in CETP activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe56385c779cfba61a2a9e19b98cf7e
Autor:
Elisabeth von der Mark, Johannes Aebi, Yu-Hua Ji, Henrietta Dehmlow, Olivier Morand, Jacques Himber, Synese Jolidon
Publikováno v:
Journal of medicinal chemistry. 46(15)
New orally active non-terpenoic inhibitors of human 2,3-oxidosqualene cyclase (hOSC) are reported. The starting point for the optimization process was a set of compounds derived from a fungicide project, which in addition to showing high affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c263528402a5a008aa43bbc2c92b7dc
https://pubmed.ncbi.nlm.nih.gov/12852766
https://pubmed.ncbi.nlm.nih.gov/12852766