Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Elisabeth Zinser"'
Autor:
Katrin Peckert-Maier, Pia Langguth, Astrid Strack, Lena Stich, Petra Mühl-Zürbes, Christine Kuhnt, Christina Drassner, Elisabeth Zinser, Marius Wrage, Jochen Mattner, Alexander Steinkasserer, Dmytro Royzman, Andreas B. Wild
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Excessive macrophage (Mφ) activation results in chronic inflammatory responses or autoimmune diseases. Therefore, identification of novel immune checkpoints on Mφ, which contribute to resolution of inflammation, is crucial for the development of ne
Externí odkaz:
https://doaj.org/article/1a0d798c26b848068ab4b38b25d588a3
Autor:
Dmytro Royzman, Katrin Peckert-Maier, Lena Stich, Christina König, Andreas B. Wild, Miyuki Tauchi, Christian Ostalecki, Franklin Kiesewetter, Stefan Seyferth, Geoffrey Lee, Sabine A. Eming, Maximilian Fuchs, Meik Kunz, Ewa K. Stürmer, Eva M. J. Peters, Carola Berking, Elisabeth Zinser, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
To facilitate the recovery process of chronic and hard-to-heal wounds novel pro-resolving treatment options are urgently needed. We investigated the pro-regenerative properties of soluble CD83 (sCD83) on cutaneous wound healing, where sCD83 accelerat
Externí odkaz:
https://doaj.org/article/1c5189c1d0044a92a854191e8b60e1a3
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp
Externí odkaz:
https://doaj.org/article/576ad5b73c124cb0990703d4d392cc97
Autor:
Jung-Hyun Lee, Christian Ostalecki, Timo Oberstein, Stefan Schierer, Elisabeth Zinser, Martin Eberhardt, Katja Blume, Bianca Plosnita, Lena Stich, Heiko Bruns, Roland Coras, Julio Vera-Gonzales, Manuel Maler, Andreas S. Baur
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103903- (2022)
Summary: Background: Plasma extracellular vesicles (pEV) can harbor a diverse array of factors including active proteases and the amyloid-precursor-protein (APP) cleavage product Aβ, involved in plaque formation in Alzheimer`s diseases (AD). A poten
Externí odkaz:
https://doaj.org/article/0ef1dff6be234781983852ab5596a110
Autor:
Linda Grosche, Ilka Knippertz, Christina König, Dmytro Royzman, Andreas B. Wild, Elisabeth Zinser, Heinrich Sticht, Yves A. Muller, Alexander Steinkasserer, Matthias Lechmann
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The CD83 molecule has been identified to be expressed on numerous activated immune cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils. Both isoforms of CD83, the membrane-bound as well as its soluble form are
Externí odkaz:
https://doaj.org/article/fb3c408893074d5eb6e59205ef14a175
Autor:
Elisabeth Zinser, Ronald Naumann, Andreas B. Wild, Julia Michalski, Andrea Deinzer, Lena Stich, Christine Kuhnt, Alexander Steinkasserer, Ilka Knippertz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The CD83 is a type I membrane protein and part of the immunoglobulin superfamily of receptors. CD83 is involved in the regulation of antigen presentation and dendritic cell dependent allogeneic T cell proliferation. A soluble form of CD83 inhibits de
Externí odkaz:
https://doaj.org/article/ee74b555661043379c0e8558e43ca12c
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Manfred Rauh, Tobias Bäuerle, Stephan Ellmann, Louis Boon, Markus Kindermann, Katrin Peckert, Aline Bozec, Georg Schett, Alexander Steinkasserer, Elisabeth Zinser
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Interference with autoimmune-mediated cytokine production is a key yet poorly developed approach to treat autoimmune and inflammatory diseases such as rheumatoid arthritis. Herein, we show that soluble CD83 (sCD83) enhances the resolution of autoimmu
Externí odkaz:
https://doaj.org/article/aad69cc2db014653827f30160fbd18d1
Autor:
Anna Hammer, Anne Waschbisch, Ilka Knippertz, Elisabeth Zinser, Johannes Berg, Stefanie Jörg, Kristina Kuhbandner, Christina David, Jingbo Pi, Antonios Bayas, De-Hyung Lee, Aiden Haghikia, Ralf Gold, Alexander Steinkasserer, Ralf A. Linker
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
To date, the intracellular signaling pathways involved in dendritic cell (DC) function are poorly understood. The antioxidative transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) has been shown to affect maturation, function, and
Externí odkaz:
https://doaj.org/article/39595151b62e44458de4f9c1455f67cc
Autor:
Thomas Winkler, Elena Percivalle, Dmytro Royzman, Falk Nimmerjahn, Vanessa Popp, Alexander Steinkasserer, Marina A Korn, Stefanie Brey, Elisabeth Zinser, Lars Nitschke, Michaela Seeling, Heike Schmitt, David Chambers, Sieglinde Angermüller, Uwe Thorsten Lux, Tobias Bäuerle, Christin Brückner
Publikováno v:
The Journal of Immunology. 205:2595-2605
Siglec-15 is a conserved sialic acid–binding Ig-like lectin, which is expressed on osteoclasts. Deficiency of Siglec-15 leads to an impaired osteoclast development, resulting in a mild osteopetrotic phenotype. The role of Siglec-15 in arthritis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb1be2ed2379a526aa3eb3eedfc4590
https://doi.org/10.4049/jimmunol.2000472
https://doi.org/10.4049/jimmunol.2000472
Autor:
Katrin Peckert-Maier, Dmytro Royzman, Pia Langguth, Anita Marosan, Astrid Strack, Atefeh Sadeghi Shermeh, Alexander Steinkasserer, Elisabeth Zinser, Andreas B. Wild
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 732, p 732 (2022)
International Journal of Molecular Sciences, Vol 23, Iss 732, p 732 (2022)
Chronic inflammatory diseases and transplant rejection represent major challenges for modern health care. Thus, identification of immune checkpoints that contribute to resolution of inflammation is key to developing novel therapeutic agents for those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7623f012db6787ebddaad21fb6a44526
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/20615
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/20615
