A randomised controlled trial comparing palate surgery at 6 months versus 12 months of age (the TOPS trial): a statistical analysis plan

Autor: Elizabeth J. Conroy, Rachael Cooper, William Shaw, Christina Persson, Elisabeth Willadsen, Kevin J. Munro, Paula R. Williamson, Gunvor Semb, Tanya Walsh, Carrol Gamble, On behalf of the TOPS trial management group

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-15 (2021)

Abstract Background Cleft palate is among the most common birth abnormalities. The success of primary surgery in the early months of life is crucial for successful feeding, hearing, dental development, and facial growth. Over recent decades, age at p

Externí odkaz: https://doaj.org/article/13078577edd24766bc62808eb8b5c330

Inter-rater reliability in classification of canonical babbling status based on canonical babbling ratio in infants with isolated cleft palate randomised to Timing of Primary Surgery for Cleft Palate (TOPS)

Autor: Elisabeth Willadsen, Rachael Cooper, ElizaBeth Conroy, Carrol Gamble, Liz Albery, Helene Andersen, Malin Appelqvist, Pia Bodling, Melanie Bowden, Karin Brunnegard, Josefin Enfalt, Stephanie van Eeden, Cristina Goncalves, Ana Fukushiro, Line Jørgensen, Jorunn Lemvik, Louise Leturgie, Eva Liljerehn, Natalie Lodge, Siobhan McMahon, Haline Miguel, Kathryn Patrick, Ginette Phippen, Silvia Piazentin-Penna, Lucy Southby, Ann-Sofie Taleman, Jorid Tangstad, Renata Yamashita, William Shaw, Kevin Munro, Tanya Walsh, Christina Persson

Publikováno v: Willadsen, E, Cooper, R, Conroy, E, Gamble, C, Albery, L, Andersen, H, Appelqvist, M, Bodling, P, Bowden, M, Brunnegard, K, Enfalt, J, Van Eeden, S, Goncalves, C, Fukushiro, A, Jørgensen, L, Lemvik, J, Leturgie, L, Liljerehn, E, Lodge, N, Mcmahon, S, Miguel, H, Patrick, K, Phippen, G, Piazentin-penna, S, Southby, L, Taleman, A, Tangstad, J, Yamashita, R, Shaw, W, Munro, K, Walsh, T & Persson, C 2022, ' Inter-rater reliability in classification of canonical babbling status based on canonical babbling ratio in infants with isolated cleft palate randomised to Timing of Primary Surgery for Cleft Palate (TOPS) ', Clinical LInguistics and Phonetics, pp. 1-22 . https://doi.org/10.1080/02699206.2021.2012259

Canonical babbling (CB) is commonly defined as present when at least 15% of all syllables produced are canonical, in other words a canonical babbling ratio (CBR) ≥0.15. However, there is limited knowledge about inter-rater reliability in classifica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047a63f35e1c4663dbfe3b0f005510ca

Longitudinal study of the development of obstruent correctness from ages 3 to 5 years in 108 Danish children with unilateral cleft lip and palate: a sub‐study within a multicentre randomized controlled trial

Autor: Line Dahl Jørgensen, Elisabeth Willadsen

Publikováno v: University of Copenhagen

Background Speech-sound development in preschoolers with unilateral cleft lip and palate (UCLP) as a group is delayed/disordered, and obstruents comprise the most vulnerable sound class. Aims To evaluate the development of obstruent correctness (PCC-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c4b669cc08f4c70c6fcaf768280ec5
https://doi.org/10.1111/1460-6984.12508

A randomised controlled trial comparing palate surgery at 6 months versus 12 months of age (the TOPS trial): a statistical analysis plan

Autor: Carrol Gamble, Paula R Williamson, Rachael Cooper, Tanya Walsh, Gunvor Semb, Christina Persson, William C. Shaw, Elisabeth Willadsen, Elizabeth J Conroy, Kevin J. Munro

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-15 (2021)
Trials
TRIALS
Conroy, E J, Cooper, R, Shaw, W, Persson, C, Willadsen, E, Munro, K J, Williamson, P R, Semb, G, Walsh, T & Gamble, C 2021, ' A randomised controlled trial comparing palate surgery at 6 months versus 12 months of age (the TOPS trial): a statistical analysis plan ', Trials, vol. 22, no. 1 . https://doi.org/10.1186/s13063-020-04886-y

Background Cleft palate is among the most common birth abnormalities. The success of primary surgery in the early months of life is crucial for successful feeding, hearing, dental development, and facial growth. Over recent decades, age at palatal su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a7f415084cef0a51beb87f320fefe1
https://doi.org/10.1186/s13063-020-04886-y

Scandcleft Project Trial 3: Comparison of Speech Outcomes in Relation to Sequence in 2-Stage Palatal Repair Procedures in 5-Year-Olds With Unilateral Cleft Lip and Palate

Autor: Christine Hayden, Anette Lohmander, Christina Persson, Melanie Bowden, Elisabeth Willadsen, David Withby, Hallvard Vindenes, Frank Åbyholm, Ragnhild Aukner, Nina-Helen Pedersen

Publikováno v: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 57(3)

Objective: To compare speech outcome following different sequencing of hard and soft palate closure between arms and centers within trial 3 and compare results to peers without cleft palate. Design: A prospective randomized clinical trial. Setting: T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bc6972121298b4c6c2de9b655928ca
https://pubmed.ncbi.nlm.nih.gov/31928085