Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Elisabeth Sievers"'
Autor:
Sven Perner, Jutta Kirfel, David Adler, Maria A. Svensson, Stefan Duensing, Peter Brossart, Ove Andrén, Jessica Carlsson, Ignacija Vlasic, Elisabeth Sievers, Wenzel Vogel, Axel S. Merseburger, Isabella Syring, Christine Sanders, Angela Queisser, Mario Deng, Diana Böhm, Anne von Mässenhausen, Anne Offermann, Niklas Klümper, Johannes Brägelmann
Purpose:The Mediator complex is a multiprotein assembly, which serves as a hub for diverse signaling pathways to regulate gene expression. Because gene expression is frequently altered in cancer, a systematic understanding of the Mediator complex in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bc946a951ea14ec379f66aa326524f
https://doi.org/10.1158/1078-0432.c.6525383.v1
https://doi.org/10.1158/1078-0432.c.6525383.v1
Autor:
Sven Perner, Jutta Kirfel, David Adler, Maria A. Svensson, Stefan Duensing, Peter Brossart, Ove Andrén, Jessica Carlsson, Ignacija Vlasic, Elisabeth Sievers, Wenzel Vogel, Axel S. Merseburger, Isabella Syring, Christine Sanders, Angela Queisser, Mario Deng, Diana Böhm, Anne von Mässenhausen, Anne Offermann, Niklas Klümper, Johannes Brägelmann
Supplementary Data from Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d8f017ad7a804a24bc8304a8f44fe0
https://doi.org/10.1158/1078-0432.22463369
https://doi.org/10.1158/1078-0432.22463369
Autor:
Wolfgang Hartmann, Reinhard Büttner, Eva Wardelmann, Gunhild Mechtersheimer, Peter Schirmacher, Hiroshi Sonobe, Shinya Tanaka, Akira Kawai, Olle Larsson, Roland Penzel, Lukas Heukamp, Peter Wurst, Elmar Endl, Susanne Steiner, Jutta Kirfel, Nicolaus Friedrichs, Marcus Renner, Sebastian Huss, Dagmar Kindler, Elisabeth Sievers, Marcel Trautmann, Sebastian Michels
PDF file - 17K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cef755d429677cdb31d1f7880066b52
https://doi.org/10.1158/0008-5472.22399080.v1
https://doi.org/10.1158/0008-5472.22399080.v1
Autor:
Wolfgang Hartmann, Reinhard Büttner, Eva Wardelmann, Gunhild Mechtersheimer, Peter Schirmacher, Hiroshi Sonobe, Shinya Tanaka, Akira Kawai, Olle Larsson, Roland Penzel, Lukas Heukamp, Peter Wurst, Elmar Endl, Susanne Steiner, Jutta Kirfel, Nicolaus Friedrichs, Marcus Renner, Sebastian Huss, Dagmar Kindler, Elisabeth Sievers, Marcel Trautmann, Sebastian Michels
PDF file - 57K, Significant decrease of p-(Tyr416)-SRC levels upon siRNA-mediated knockdown of IGF-1R in CME-1 synovial sarcoma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0742c56add85712b2048fcf739ffc30c
https://doi.org/10.1158/0008-5472.22399083
https://doi.org/10.1158/0008-5472.22399083
Autor:
Wolfgang Hartmann, Reinhard Büttner, Eva Wardelmann, Gunhild Mechtersheimer, Peter Schirmacher, Hiroshi Sonobe, Shinya Tanaka, Akira Kawai, Olle Larsson, Roland Penzel, Lukas Heukamp, Peter Wurst, Elmar Endl, Susanne Steiner, Jutta Kirfel, Nicolaus Friedrichs, Marcus Renner, Sebastian Huss, Dagmar Kindler, Elisabeth Sievers, Marcel Trautmann, Sebastian Michels
PDF file - 70K, As an indirect proof of specific SRC-related action of dasatinib in synovial sarcoma cells, CME-1 did not display any significant effects upon dasatinib treatement after siRNA-mediated SRC-knockdown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3778531c97620070ef2d591489bb0218
https://doi.org/10.1158/0008-5472.22399086
https://doi.org/10.1158/0008-5472.22399086
Autor:
Wolfgang Hartmann, Reinhard Büttner, Eva Wardelmann, Gunhild Mechtersheimer, Peter Schirmacher, Hiroshi Sonobe, Shinya Tanaka, Akira Kawai, Olle Larsson, Roland Penzel, Lukas Heukamp, Peter Wurst, Elmar Endl, Susanne Steiner, Jutta Kirfel, Nicolaus Friedrichs, Marcus Renner, Sebastian Huss, Dagmar Kindler, Elisabeth Sievers, Marcel Trautmann, Sebastian Michels
PDF file - 57K, Densitometric analysis of the top five phosphorylated kinases as found in phospho kinase arrays in 1273/99 and HS-SY-II synovial sarcoma cells. Flow cytometric analysis of three synovial sarcoma cell lines treated with different doses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adce403c7451e866f030d31e2ece61e0
https://doi.org/10.1158/0008-5472.22399077.v1
https://doi.org/10.1158/0008-5472.22399077.v1
Autor:
Anna-Lena Lemster, Elisabeth Sievers, Helen Pasternack, Pamela Lazar-Karsten, Niklas Klümper, Verena Sailer, Anne Offermann, Johannes Brägelmann, Sven Perner, Jutta Kirfel
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 1894
Prostate cancer (PCa) poses a major public health problem in men. Metastatic PCa is incurable, and ultimately threatens the life of many patients. Mutations in tumor suppressor genes and oncogenes are important for PCa progression, whereas the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a020cee8d2731408df8fed6b51b8d9d
https://pubmed.ncbi.nlm.nih.gov/35454801
https://pubmed.ncbi.nlm.nih.gov/35454801
Autor:
Roland Schüle, Magdalena Rohde, Andreas Janzer, Jutta Kirfel, Dominica Willmann, Hubert Schorle, Angela Egert, Elisabeth Sievers
Publikováno v:
Experimental Cell Research. 348:123-131
Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing, immune responses and invasive tumors all require the orchestrated movement of cells to sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0029114a86485eadfdb331d3b01513c
https://doi.org/10.1016/j.yexcr.2016.08.026
https://doi.org/10.1016/j.yexcr.2016.08.026
Autor:
Marcus Renner, Uta Dirksen, Gunhild Mechtersheimer, Wolfgang Hartmann, Elisabeth Sievers, Jun Nishio, Inga Gruenewald, Marcel Trautmann, Reinhard Buettner, Eva Wardelmann, Sebastian Huss, Peter Schirmacher, Hans-Ulrich Schildhaus, Pierre Åman, Florence Pedeutour, Jutta Kirfel, Dagmar Kindler
Publikováno v:
International Journal of Cancer. 137:2578-2588
Liposarcomas (LS) are the most common malignant mesenchymal tumors, with an overall long-term mortality rate of 60%. LS comprise three major subtypes, i.e., well-differentiated/dedifferentiated liposarcoma (WDLS/DDLS), myxoid/round cell liposarcoma (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cea5782d7533ea129ba3fbde5b18bf0c
https://doi.org/10.1002/ijc.29645
https://doi.org/10.1002/ijc.29645
Autor:
Diana Böhm, Sven Perner, Axel S. Merseburger, Elisabeth Sievers, Angela Queisser, Jessica Carlsson, Christine Sanders, Isabella Syring, Ignacija Vlasic, Maria A. Svensson, Wenzel Vogel, Johannes Brägelmann, Niklas Klümper, Anne von Mässenhausen, Mario C. Deng, Anne Offermann, Peter Brossart, Zaki Shaikhibrahim, Ove Andrén, Jutta Kirfel, Stefan Duensing
Purpose: The Mediator complex is a multiprotein assembly, which serves as a hub for diverse signaling pathways to regulate gene expression. Because gene expression is frequently altered in cancer, a systematic understanding of the Mediator complex in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc748dfdd83ab9f8e0a6c098b9b7dd7
https://doi.org/10.1158/1078-0432.ccr-16-0094
https://doi.org/10.1158/1078-0432.ccr-16-0094