Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Elisabeth Südhoff"'
Autor:
Patrick Niekamp, Felix Scharte, Tolulope Sokoya, Laura Vittadello, Yeongho Kim, Yongqiang Deng, Elisabeth Südhoff, Angelika Hilderink, Mirco Imlau, Christopher J. Clarke, Michael Hensel, Christopher G. Burd, Joost C. M. Holthuis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Activation of ESCRT prevents potentially lethal outcomes of minor perturbations in lysosomal integrity. Here authors show that Ca2 + -activated scrambling of sphingomyelin and its cytosolic turnover drives lysosomal repair independently of ESCRT.
Externí odkaz:
https://doaj.org/article/8782aaf4d7804bac8f2c73df7fa64a62
Autor:
Patrick, Niekamp, Felix, Scharte, Tolulope, Sokoya, Laura, Vittadello, Yeongho, Kim, Yongqiang, Deng, Elisabeth, Südhoff, Angelika, Hilderink, Mirco, Imlau, Christopher J, Clarke, Michael, Hensel, Christopher G, Burd, Joost C M, Holthuis
Publikováno v:
Nature communications. 13(1)
Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell viability. Here we report that cells exploit a sphingomyelin-based lysosomal repair pathway that ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71b1f73979ae3e2298731237ae1ace5d
https://pubmed.ncbi.nlm.nih.gov/35388011
https://pubmed.ncbi.nlm.nih.gov/35388011