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pro vyhledávání: '"Elisabeth Philipps"'
Autor:
Christina Wohlrab, Margreet C.M. Vissers, Eleanor R. Burgess, Maria Nonis, Elisabeth Philipps, Bridget A. Robinson, Gabi U. Dachs
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 5, Pp 553-568 (2021)
Externí odkaz:
https://doaj.org/article/1473a972c7014329a1b67231439a07e0
Autor:
Hugo M. Vargas, Smita Patel, Kevin John Merchant, Angus Murray Macleod, T. Ladduwahetty, L. Rebecca Fish, Elisabeth Philipps, Magnus Ivarsson, Peter H. Hutson, Myra Gilligan, Desmond O'Connor, Alexander Charles Humphries
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:3665-3669
Incorporation of fluorine at the 4-position of an existing series of sulfonyl piperidine 5-HT2A antagonists gave compounds with increased selectivity over the IKr potassium channel. This work led to the identification of 3b, a compound that gave no i