Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Elisabeth Perez"'
Autor:
Maite Alvarez, Itziar Otano, Luna Minute, Maria Carmen Ochoa, Elisabeth Perez-Ruiz, Ignacio Melero, Pedro Berraondo
Publikováno v:
Cell Stress, Vol 3, Iss 7, Pp 236-239 (2019)
The TNF blockade therapy is currently a well-established treatment option for a variety of autoimmune diseases such as rheumatoid arthritis (RA), psoriasis or Crohn’s disease, given the proinflammatory role of TNF in the course of these diseases. I
Externí odkaz:
https://doaj.org/article/df119cc966a8481a88cd8ca42b49ab21
Autor:
Miguel-Angel Berciano-Guerrero, Mora Guardamagna, Elisabeth Perez-Ruiz, Jose-Miguel Jurado, Isabel Barragán, Antonio Rueda-Dominguez
Publikováno v:
Life, Vol 12, Iss 9, p 1302 (2022)
Metastatic melanoma (MM) is a pathological entity with a very poor prognosis that, until a few decades ago, had a low response rate to systemic treatments. Fortunately, in the last few years, new therapies for metastatic melanoma have emerged. Curren
Externí odkaz:
https://doaj.org/article/fbe0ab79699b4547b29a3613b3c82678
Autor:
Miguel-Angel Berciano-Guerrero, Rocío Lavado-Valenzuela, Aurelio Moya, Luis delaCruz-Merino, Fátima Toscano, Javier Valdivia, Victoria Castellón, Fernando Henao-Carrasco, Pilar Sancho, Juan-Luis Onieva-Zafra, Ismael Navas-Delgado, Antonio Rueda-Dominguez, Elisabeth Perez-Ruiz, Emilio Alba
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 284 (2022)
Targeted therapy in metastatic melanoma often achieves a major tumour regression response and significant long-term survival via the release of antigens that reinduce immunocompetence. The biomarkers thus activated may guide the prediction of respons
Externí odkaz:
https://doaj.org/article/18a4039dc9494c71a63c0c1a8eff1060
Autor:
Maria C. Ochoa, Elisabeth Perez-Ruiz, Luna Minute, Carmen Oñate, Guiomar Perez, Inmaculada Rodriguez, Aintzane Zabaleta, Diego Alignani, Myriam Fernandez-Sendin, Ascension Lopez, Aura Muntasell, Miguel F. Sanmamed, Bruno Paiva, Miguel Lopez-Botet, Pedro Berraondo, Ignacio Melero
Publikováno v:
OncoImmunology, Vol 8, Iss 7 (2019)
Daratumumab is an anti-CD38 fully human IgG1 mAb approved for multiple myeloma treatment. One of the proposed mechanisms of action is the induction of antibody-dependent cellular cytotoxicity (ADCC) mediated by NK cells. NK cells acquire surface CD13
Externí odkaz:
https://doaj.org/article/469445f7b4c148028345cf1278b80df7
Autor:
Maria Garrido-Barros, Javier Oliver, Juan Luis Onieva, Beatriz Martinez-Galvez, Jaime Duddelman, Antonio Rueda, Elisabeth Perez, Emilio Alba, Inmaculada Ramos, Juan Zafra, Manuel Cobo, Isabel Barragán
Publikováno v:
Cancer Research. 83:3746-3746
Immunotherapy based on Immune Checkpoint blockade (ICB) has become a significant therapeutic option for advanced Non Small Cell Lung Cancer (NSCLC) patients. However, there is an urgent need to find novel biomarkers that to reliably stratify good res
Autor:
Isabel Barragan, Elisabeth Perez-Ruiz, Juan Luis Onieva, Maria Garrido-Ramos, Beatriz Martinez-Galvez, Jaime Dubbelman, Emilio Alba, Juan Zafra, Manuel Cobo, Javier Oliver, Antonio Rueda-Dominguez
Publikováno v:
Cancer Research. 83:1044-1044
The irruption of the immunotherapy for the treatment of non-small cell lung cancer (NSCLC) based on Immune Checkpoint Inhibitors (ICI) PD-1 and PD-L1 inhibitors is considered a treatment revolution. However, only a small percentage of patients benefi
Autor:
Niki Karachaliou, Maria Gonzalez-Cao, Guillermo Crespo, Ana Drozdowskyj, Erika Aldeguer, Ana Gimenez-Capitan, Cristina Teixido, Miguel Angel Molina-Vila, Santiago Viteri, Maria De Los Llanos Gil, Salvador Martin Algarra, Elisabeth Perez-Ruiz, Ivan Marquez-Rodas, Delvys Rodriguez-Abreu, Remedios Blanco, Teresa Puertolas, Maria Angeles Royo, Rafael Rosell
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 10 (2018)
Background: Programmed death-ligand 1 (PD-L1) may be induced by oncogenic signals or can be upregulated via interferon gamma (IFN-γ). We have explored whether the expression of IFNG, the gene encoding IFN-γ, is associated with clinical response to
Externí odkaz:
https://doaj.org/article/8ac2c8fef28b486789e2a6c0357c1a10
Autor:
Nathalie Elisabeth Perez, Neha Pradyumna Godbole, Katherine Amin, Raveen Syan, David R. Gater
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 6; Pages: 968
Urinary incontinence is common after spinal cord injury (SCI) due to loss of supraspinal coordination and unabated reflexes in both autonomic and somatic nervous systems; if unchecked, these disturbances can become life-threatening. This manuscript w
Autor:
Javier Oliver, Juan Luis Onieva, Maria Garrido-Barros, Alicia Garrido-Aranda, Vanessa De Luque, Martina Alvarez, Alfonso Sanchez, Elisabeth Perez, Patricia Chaves, Maria Jose Lozano, Miguel Berciano, Manolo Cobo, Emilio Alba, Antonio Rueda, Isabel Barragan
Publikováno v:
Cancer Research. 82:1538-1538
Cutaneous melanoma (CM) is an aggressive malignant tumor of epidermal melanocytes for which treatment options and survival chances decrease dramatically when metastatic. To date, immunotherapy is becoming a new standard treatment for CM although less
Autor:
Lucia Trilla-Fuertes, Guillermo Prado-Vazquez, Angelo Gámez-Pozo, Rocio Lopez-Vacas, Maria Isabel Lumbreras Herrera, Virtudes Soriano, Fernando Garicano, Maria Jose Lecumberri, Maria Rodriguez, Margarita Majem, Elisabeth Perez, Maria Gonzalez-Cao, Juana Oramas, Alejandra Magdaleno, Joaquin Fra, Alfonso Martin, Monica Corral, Teresa Puertolas, Juan Angel Fresno Vara, Enrique Espinosa
Publikováno v:
Cancer Research. 82:5416-5416
Background: Prediction of response to immunotherapy remains an unmet need in the field of advanced melanoma. Methods: Computational analyses, including probabilistic graphical models, sparse k-means, and consensus cluster, were used to characterize m