Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Elisabeth Odin"'
Autor:
Helena Taflin, Elisabeth Odin, Göran Carlsson, Bengt Gustavsson, Yvonne Wettergren, Elinor Bexe Lindskog
Publikováno v:
Cancers, Vol 15, Iss 1, p 258 (2022)
The combination of 5-fluorouracil (5-FU) and leucovorin (LV) forms the chemotherapy backbone for patients with colorectal cancer. However, the LV administration is often standardized and not based on robust scientific data. To address these issues, a
Externí odkaz:
https://doaj.org/article/a0f6f526129540c1a2ebf8c3b5319203
Publikováno v:
Tumor Biology, Vol 41 (2019)
5-fluorouracil in combination with the folate leucovorin is the cornerstone in treatment of colorectal cancer. Transport of leucovorin into cells, and subsequent metabolic action, require expression of several genes. The aim was to analyze if tumoral
Externí odkaz:
https://doaj.org/article/c2834e36a1bd474489abc32cbdd04d7b
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2014, Iss 8, Pp 15-20 (2014)
Externí odkaz:
https://doaj.org/article/2fa36e3730cc4cb3803f2a44ed38af92
Autor:
Elinor B. Lindskog, Yvonne Wettergren, Elisabeth Odin, Bengt Gustavsson, Kristoffer Derwinger
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2012, Iss 6, Pp 347-353 (2012)
Externí odkaz:
https://doaj.org/article/242caafbc0044b9cae4d66d9b7c69384
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 8 (2014)
Aim The aim of the study was to explore and describe the effect of polymorphisms in folate-associated genes regarding the levels of different folate forms and their distribution in tumors and mucosa in patients with colorectal cancer. Materials and M
Externí odkaz:
https://doaj.org/article/a0b8da00a48c490882620535a388e91c
Autor:
Helena Taflin, Elisabeth Odin, Göran Carlsson, Bengt Gustavsson, Yvonne Wettergren, Elinor Bexe Lindskog
Publikováno v:
European Journal of Surgical Oncology. 49:e113-e114
Autor:
Elisabeth Odin, Göran Carlsson, Helena Taflin, Roger Tell, Bengt Gustavsson, Yvonne Wettergren
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose The aim was to explore the correlation between increasing doses of [6R]-5,10-methylenetetrahydrofolate (arfolitixorin) and plasma concentrations of deoxyuridine (dUr) in patients with metastatic colorectal cancer (mCRC), subjected to 5-fluoro
Autor:
Helena Taflin, Sofia Westermark, Peter Naredi, Yvonne Wettergren, Oskar Hemmingsson, Elisabeth Odin, Mikael Öman
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose The aim was to investigate the pharmacokinetics of preoperatively administered intraperitoneal (IP) 5-FU in patients with resectable pancreatic ductal adenocarcinoma (PDAC) by analyzing levels of 5-FU and target metabolites in peritoneal flui
Autor:
Roger Tell, Pushpa Saksena, Bengt Gustavsson, Alessandro Di Cara, Yvonne Wettergren, Anders Edsjö, Elisabeth Odin, Göran Carlsson
Publikováno v:
Cancer Research. 81:346-346
Background - 5-fluorouracil (5-FU) in combination with the folate leucovorin (LV) has formed the backbone of chemotherapy for advanced colorectal cancer for several decades. A number of genes encode proteins that participate in transportation of LV i
Publikováno v:
Journal of Clinical Oncology. 39:99-99
99 Background: Arfolitixorin is the natural, biologically active form of the marketed folates and is expected to be efficacious in a larger proportion of patients with less inter- and intra-individual variability compared with e.g. leucovorin. We hav