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pro vyhledávání: '"Elisabeth Maria Bissinger"'
Autor:
Manfred Jung, Alexander-Thomas Hauser, Eric Metzger, Roland Schüle, Antonello Mai, Uta-Maria Bauer, Elisabeth-Maria Bissinger, Antje Repenning
Publikováno v:
SLAS Discovery. 17:18-26
In the past years, a lot of attention has been given to the identification and characterization of selective and potent inhibitors of chromatin-modifying enzymes to better understand their specific role in transcriptional regulation. As aberrant hist
Autor:
Elisabeth Maria Bissinger, V. Cura, Mark T. Bedford, Jean Cavarelli, Adrien Eberlin, Manfred Jung, Astrid Spannhoff, Eric Metzger, Wolfgang Sippl, Roland Schüle, Pierre Hassenboehler, Ralf Heinke
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:3717-3731
Arginine methylation is an epigenetic modification that receives increasing interest as it plays an important role in several diseases. This is especially true for hormone-dependent cancer, seeing that histone methylation by arginine methyltransferas
Publikováno v:
MedChemComm. 1:114-124
The term epigenetics is defined as inheritable changes that influence the outcome of a phenotype without changes in the genome. Epigenetics is based upon DNA methylation and posttranslational histone modifications. While there is much known about rev