Výsledky vyhledávání - "Elisabeth M. Shiffer"

Akademický článek

Parainfluenza Virus 5 V Protein Blocks Interferon Gamma-Mediated Upregulation of NK Cell Inhibitory Ligands and Improves NK Cell Killing of Neuroblastoma Cells

Autor: Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja J. Copik, Griffith D. Parks

Publikováno v: Viruses, Vol 16, Iss 8, p 1270 (2024)

Natural killer (NK) cells can be effective immunotherapeutic anti-cancer agents due to their ability to selectively target and kill tumor cells. This activity is modulated by the interaction of NK cell receptors with inhibitory ligands on the surface

Externí odkaz: https://doaj.org/article/5d77f5493d7548818ab809e97de35206

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DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus

Autor: Kritika Kedarinath, Elisabeth M. Shiffer, Griffith D. Parks

Publikováno v: Anti-Cancer Drugs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e6535c1440422a565c562201deb4805
https://doi.org/10.1097/cad.0000000000001525

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Delivery of a novel membrane-anchored Fc chimera enhances NK cell-mediated killing of tumor cells and persistently virus-infected cells

Autor: Namita Varudkar, Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja Copik, Griffith D. Parks

Publikováno v: PLOS ONE. 18:e0285532

Antibody-dependent cellular cytotoxicity (ADCC) is one of the most powerful mechanisms for Natural Killer (NK) cells to kill cancer cells or virus-infected cells. A novel chimeric protein (NA-Fc) was created, which when expressed in cells, positions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::491ca268554ee36c438051faebda7280
https://doi.org/10.1371/journal.pone.0285532

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