The identification of genetic pathways involved in vascular adaptations after physical deconditioningversusexercise training in humans

Autor: Thomas W. J. Janssen, Arnold de Haan, Dick H. J. Thijssen, Eugène T P Verwiel, Elisabeth M. Pardoel, Astrid M. Horstman, Maria T. E. Hopman, Gerwen Lammers, Joost G. J. Hoenderop, Mark J. J. de Graaf, Noortje T. L. van Duijnhoven

Publikováno v: Experimental Physiology. 98:710-721

Weusedauniquestudydesigntoexaminebothvascularcharacteristicsofthesuperficialfemoral artery (using ultrasound) and gene expression levels (from a muscle biopsy) in human models for physical deconditioning and exercise training. Initially, we compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2574046359f6ba167818fdd4f35b0962
https://doi.org/10.1113/expphysiol.2012.068726

The identification of genetic pathways involved in vascular adaptations after physical deconditioning versus exercise training in humans

Autor: Gerwen, Lammers, Noortje T L, van Duijnhoven, Joost G, Hoenderop, Astrid M, Horstman, Arnold, de Haan, Thomas W J, Janssen, Mark J J, de Graaf, Elisabeth M, Pardoel, Eugène T P, Verwiel, Dick H J, Thijssen, Maria T E, Hopman

Publikováno v: Experimental physiology. 98(3)

Physical inactivity and exercise training result in opposite adaptations of vascular structure. However, the molecular mechanisms behind these adaptations are not completely understood. We used a unique study design to examine both vascular character

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e0fc2c5a3b07f757f98dee9dd504ad4
https://pubmed.ncbi.nlm.nih.gov/23064509

Expression of genes involved in fatty acid transport and insulin signaling is altered by physical inactivity and exercise training in human skeletal muscle

Autor: Noortje T. L. van Duijnhoven, Fleur Poelkens, Elisabeth M. Pardoel, Maria T. E. Hopman, Dick H. J. Thijssen, Gerwen Lammers, Joost G. J. Hoenderop

Publikováno v: American Journal of Physiology : Endocrinology and Metabolism, 303, 10, pp. E1245-51
American Journal of Physiology : Endocrinology and Metabolism, 303, E1245-51

Item does not contain fulltext Physical deconditioning is associated with the development of chronic diseases, including type 2 diabetes and cardiovascular disease. Exercise training effectively counteracts these developments, but the underlying mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c7b00e36120ac412694026b076640c
https://hdl.handle.net/2066/107845