Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elisabeth Leßmann"'
Autor:
Josefine Metzkes-Ng, Florian-Emanuel Brack, Florian Kroll, Constantin Bernert, Stefan Bock, Elisabeth Bodenstein, Michael Brand, Thomas E. Cowan, René Gebhardt, Stefan Hans, Uwe Helbig, Felix Horst, Jeannette Jansen, Stephan D. Kraft, Mechthild Krause, Elisabeth Leßmann, Steffen Löck, Jörg Pawelke, Thomas Püschel, Marvin Reimold, Martin Rehwald, Christian Richter, Hans-Peter Schlenvoigt, Ulrich Schramm, Michael Schürer, Joao Seco, Emília Rita Szabó, Marvin E. P. Umlandt, Karl Zeil, Tim Ziegler, Elke Beyreuther
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The recently observed FLASH effect describes the observation of normal tissue protection by ultra-high dose rates (UHDR), or dose delivery in a fraction of a second, at similar tumor-killing efficacy of conventional dose delivery and promise
Externí odkaz:
https://doaj.org/article/3adea7ce7b744f1eb0c55d7301e3c267
Autor:
Emília Rita Szabó, Michael Brand, Stefan Hans, Katalin Hideghéty, Leonhard Karsch, Elisabeth Lessmann, Jörg Pawelke, Michael Schürer, Elke Beyreuther
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206879 (2018)
The increasing use of proton radiotherapy during the last decade and the rising number of long-term survivors has given rise to a vital discussion on potential effects on normal tissue. So far, deviations from clinically applied generic RBE (relative
Externí odkaz:
https://doaj.org/article/f92a11809c72431ea2433b585265e48a
Autor:
Felix Horst, Michael Brand, Stefan Hans, Leonhard Karsch, Elisabeth Lessmann, Steffen Löck, Michael Schürer, Jörg Pawelke, Elke Beyreuther
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:1006-1007
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc388b3bb80ff95286ff1c1bb73c549
https://doi.org/10.1016/j.ijrobp.2022.11.015
https://doi.org/10.1016/j.ijrobp.2022.11.015
Autor:
Sebastian Meister, Florian Kroll, Marvin Reimold, Elisabeth Lessmann, Florian-Emanuel Brack, Josefine Metzkes-Ng, Ulrich Schramm, Jörg Pawelke, Karl Zeil, Kerstin Brüchner, Alexej Nossula, Leonhard Karsch, Stephan Kraft, Elisabeth Bodenstein, Marvin E. P. Umlandt, Elke Beyreuther, Jens Pietzsch
Publikováno v:
Laser Acceleration of Electrons, Protons, and Ions VI.
After the rediscovery of the normal tissue sparing effect of high dose rate radiation, i.e. the so-called FLASH effect, by Favaudon et al. in 2014, research activities on this topic have been revived and are flourishing ever since. Yet, the exact bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a301dac3ad4f3f64453f4b9f53dda69a
https://doi.org/10.1117/12.2589523
https://doi.org/10.1117/12.2589523
Autor:
Constantin Bernert, Marvin Elias Paul Umlandt, Karl Zeil, Hans-Peter Schlenvoigt, Stephan Kraft, Florian Kroll, Jörg Pawelke, Josefine Metzkes-Ng, Leonhard Karsch, Tim Ziegler, Ulrich Schramm, Manfred Sobiella, Elke Beyreuther, Lennart Gaus, Marvin Reimold, Thomas E. Cowan, Martin Rehwald, Elisabeth Lessmann, Florian-Emanuel Brack
Publikováno v:
Applying Laser-driven Particle Acceleration II, Medical and Nonmedical Uses of Distinctive Energetic Particle and Photon Sources: SPIE Optics + Optoelectronics Industry Event.
Laser-driven proton pulse provide unique properties in terms of pulse structure (ns) and instantaneous dose rate (10^9 Gy/s) but - inherently broadband and highly divergent - pose a challenge to established beamline concepts on the path to applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18d44da5d1d2fd93eac38b6832314c41
https://doi.org/10.1117/12.2596503
https://doi.org/10.1117/12.2596503
Publikováno v:
Neuroscience. 473
In many species, social communication and mate choice are influenced by olfactory cues associated with the major histocompatibility complex (MHC). It has been reported that humans also respond to olfactory signals related to the human MHC-equivalent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be16c4b838450bbb9210ee95b57f19f5
https://pubmed.ncbi.nlm.nih.gov/34407460
https://pubmed.ncbi.nlm.nih.gov/34407460
Autor:
Leonhard Karsch, Elisabeth Lessmann, Emília Rita Szabó, Elke Beyreuther, Michael Brand, Stefan Hans, Steffen Löck, Katalin Hideghéty, Michael Schürer, Jörg Pawelke
Publikováno v:
Radiotherapy and Oncology 158(2021), 7-12
Background and purpose In consequence of a previous study, where no protecting proton Flash effect was found for zebrafish embryos, potential reasons and requirements for inducing a Flash effect should be investigated with higher pulse dose rate and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52d6b733741173f1b23d967f8102deb
https://pubmed.ncbi.nlm.nih.gov/33587970
https://pubmed.ncbi.nlm.nih.gov/33587970
Publikováno v:
Scientific Reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::9cd17685ac6c6a26dea6932138c94851
Autor:
Emília Rita Szabó, Elke Beyreuther, Leonhard Karsch, Elisabeth Leßmann, Jörg Pawelke, Michael Schürer, Stefan Hans, Katalin Hideghéty, Michael Brand
Publikováno v:
Radiotherapy and Oncology
Radiotherapy and Oncology 139(2019), 46-50
Radiotherapy and Oncology 139(2019), 46-50
Background and purpose Motivated by first animal trials showing the normal tissue protecting effect of electron and photon Flash irradiation relative to conventional continuous beam delivery, the feasibility of proton Flash should be assessed. Materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd7c4e181b2f5b99147b82c3148422c
Autor:
Michael Schürer, Elisabeth Leßmann, Christian Richter, Leonhard Karsch, Jörg Pawelke, L. Laschinsky, Melanie Oppelt, Elke Beyreuther
Publikováno v:
Radiation and Environmental Biophysics. 55:381-391
Regarding the long-term goal to develop and establish laser-based particle accelerators for a future radiotherapeutic treatment of cancer, the radiobiological consequences of the characteristic short intense particle pulses with ultra-high peak dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40db7a032d46289771ae54e735e90bf4
https://doi.org/10.1007/s00411-016-0652-7
https://doi.org/10.1007/s00411-016-0652-7