Associations of dicarbonyl stress with complement activation

Autor: Carla J.H. van der Kallen, Marleen M.J. van Greevenbroek, Casper G. Schalkwijk, Elisabeth Hertle, Ying Xin, Coen D.A. Stehouwer

Publikováno v: Diabetologia, 63(5), 1032-1042. Springer, Cham
Diabetologia

Aims/hypothesis Reactive α-dicarbonyl compounds are major precursors of AGEs and may lead to glycation of circulating and/or cell-associated complement regulators. Glycation of complement regulatory proteins can influence their capacity to inhibit c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5faa69aacc58d442f7d2d30d06f3742
https://cris.maastrichtuniversity.nl/en/publications/359cbd29-8793-4d1f-8aa7-bdeafb58a5a2

Longitudinal associations of the alternative and terminal pathways of complement activation with adiposity: The CODAM study

Autor: Ying Xin, Elisabeth Hertle, Carla J.H. van der Kallen, Marleen M.J. van Greevenbroek, Casper G. Schalkwijk, Coen D.A. Stehouwer

Publikováno v: Obesity Research & Clinical Practice, 12(3), 286-292. Elsevier BV

Objective: To investigate longitudinal associations of components of the alternative (C3, C3a, Bb, factor D [FD], factor H [FH], and properdin) and the terminal complement pathway (C5a, sC5b-9) with adiposity. Methods: A prospective human cohort stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b4eeccc014fefda1e8901d6f9e464f
https://doi.org/10.1016/j.orcp.2017.11.002

Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study

Autor: Elisabeth Hertle, Carla J.H. van der Kallen, Ilja C. W. Arts, Ingeborg Torp Hoffmann-Petersen, Edith J. M. Feskens, Casper G. Schalkwijk, Coen D.A. Stehouwer, Marleen M.J. van Greevenbroek, Steffen Thiel

Publikováno v: Hertle, E, Arts, I C W, van der Kallen, C J H, Feskens, E J M, Schalkwijk, C G, Hoffmann-Petersen, I T, Thiel, S, Stehouwer, C D A & van Greevenbroek, M M J 2016, ' Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness : The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, no. 6, pp. 1278-85 . https://doi.org/10.1161/ATVBAHA.115.306552
Arteriosclerosis Thrombosis and Vascular Biology, 36(6), 1278-1285. LIPPINCOTT WILLIAMS & WILKINS

Objective— Previous studies suggested that the lectin-complement pathway plays a complex role in cardiovascular disease (CVD). To date, no prospective human studies have investigated the relationship between the initiating factor of the lectin path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7218f2fbe6e8ec6044eefa65390c7f84
https://doi.org/10.1161/atvbaha.115.306552

Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study

Autor: Elisabeth Hertle, Marleen M.J. van Greevenbroek, Ying Xin, Casper G. Schalkwijk, Coen D.A. Stehouwer, Carla J.H. van der Kallen

Publikováno v: Endocrine
Endocrine, 62(3), 617-627. Springer

Purpose We investigated the associations of components of the alternative (C3, C3a, Bb, factor D [FD], factor H [FH], properdin) and the classical complement pathway (C4, C1q, C1-inhibitor [C1-INH]) with prevalent and incident metabolic syndrome in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf68011b47ced7c29e8edfefbd9cfa2
https://pubmed.ncbi.nlm.nih.gov/30132263

Associations of the alternative pathway and classical pathway of complement activation with incident metabolic syndrome: The CODAM study

Autor: Ying Xin, Marleen M.J. van Greevenbroek, Elisabeth Hertle, Casper G. Schalkwijk, Coen D.A. Stehouwer, Carla J.H. van der Kallen

Publikováno v: Molecular Immunology. 89:190

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ae045b6970486f2d4610d6c91a53b2a
https://doi.org/10.1016/j.molimm.2017.06.188