Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elisabeth H. Vollmann"'
Autor:
Elisabeth H. Vollmann, Kristin Rattay, Olga Barreiro, Aude Thiriot, Rebecca A. Fuhlbrigge, Vladimir Vrbanac, Ki-Wook Kim, Steffen Jung, Andrew M. Tager, Ulrich H. von Andrian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
T cells are selected in the thymus, through interaction with self-antigens, to remove autoreactive cells. Here the authors show that a specialized thymic dendritic cell subset juxtaposes to microvessels, requires CX3CR1/CX3CL1 for this positioning, a
Externí odkaz:
https://doaj.org/article/e5a90dc309b14d17a41033c02985f06b
Autor:
Elisabeth H. Vollmann, Lizhi Cao, Aldo Amatucci, Taylor Reynolds, Stefan Hamann, Isin Dalkilic-Liddle, Thomas O. Cameron, Markus Hossbach, Kevin J. Kauffman, Faryal F. Mir, Daniel G. Anderson, Tatiana Novobrantseva, Victor Koteliansky, Tatiana Kisseleva, David Brenner, Jeremy Duffield, Linda C. Burkly
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 314-323 (2017)
Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed. We aimed to identify novel modifiers of tissue fibrosis
Externí odkaz:
https://doaj.org/article/0a07061608884d5ebedd059c50812d16
Autor:
Kristin Rattay, Ki-Wook Kim, Elisabeth H. Vollmann, Steffen Jung, Ulrich H. von Andrian, Vladimir Vrbanac, Andrew M. Tager, Rebecca A Fuhlbrigge, Olga Barreiro, Aude Thiriot
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
T cells undergo rigorous selection in the thymus to ensure self-tolerance and prevent autoimmunity, with this process requiring innocuous self-antigens (Ags) to be presented to thymocytes. Self-Ags are either expressed by thymic stroma cells or trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f1d418d4bf48b2fa8e6d4d374e6251
https://doi.org/10.1038/s41467-021-26446-x
https://doi.org/10.1038/s41467-021-26446-x
Publikováno v:
Biochemical Pharmacology
Graphical abstract
The host response to SARS-CoV-2, the virus that causes COVID-19, is highly heterogeneous, ranging from mild/asymptomatic to severe. The moderate to severe forms of COVID-19 often require hospitalization, are associated with a
The host response to SARS-CoV-2, the virus that causes COVID-19, is highly heterogeneous, ranging from mild/asymptomatic to severe. The moderate to severe forms of COVID-19 often require hospitalization, are associated with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a53e6ac51d106b2dccff0f7f608cc1f
https://doi.org/10.1016/j.bcp.2021.114847
https://doi.org/10.1016/j.bcp.2021.114847
Autor:
Xiaohua Jin, Joseph V. Bonventre, Murti Mistri, Matthew S. Chin, Brandon M. Proctor, Andrew M. Siedlecki, Ulrich H. von Andrian, Ryan J. Hoffman, Elisabeth H. Vollmann, Joseph Chung, Michelle Farley, Paul Pang, Nikita Chauhan, Mario Perro, Roy Nilay K, Anthony J. Muslin
Publikováno v:
Kidney international
Vascular inflammation is a major contributor to the severity of acute kidney injury. In the context of vasospasm-independent reperfusion injury we studied the potential anti-inflammatory role of the Gα-related RGS protein, RGS4. Transgenic RGS4 mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ca46f67dd0e0771ef6bcadfd3e994d
https://doi.org/10.1038/ki.2014.364
https://doi.org/10.1038/ki.2014.364
Autor:
Raif S. Geha, Janet Chou, Shin-Young Park, Elisabeth H. Vollmann, Christina S.K. Yee, P. Luigi Poliani, Ulrich H. von Andrian, Arturo Borzutzky, Lalit Kumar, Georg A. Holländer, John P. Manis
Publikováno v:
Journal of Experimental Medicine. 211:929-942
Lrrc8a is a ubiquitously expressed gene that encodes a leucine-rich repeat (LRR)–containing protein detected at higher levels on the surface of thymocytes than on other immune cells. We generated Lrrc8a−/− mice to investigate the role of LRRC8A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc7919c7ab79fb378e8579590cd7221
https://doi.org/10.1084/jem.20131379
https://doi.org/10.1084/jem.20131379
Autor:
Tatiana Kisseleva, Isin Dalkilic-Liddle, David A. Brenner, Tatiana Novobrantseva, Taylor L. Reynolds, Jeremy S. Duffield, Daniel G. Anderson, Victor Koteliansky, Aldo Amatucci, Elisabeth H. Vollmann, Faryal F. Mir, Stefan Hamann, Lizhi Cao, Thomas Cameron, Markus Hossbach, Linda C. Burkly, Kevin J. Kauffman
Publikováno v:
Elsevier
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 314-323 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 314-323 (2017)
Molecular Therapy. Nucleic Acids
Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed. We aimed to identify novel modifiers of tissue fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1f6bdfdf29c3e4fba79efadc80cbd0
https://hdl.handle.net/1721.1/121997
https://hdl.handle.net/1721.1/121997
Autor:
Louise M. D’Cruz, Antonius G. Rolink, Jan Emmerich, Lee Kim Swee, Ludger Klein, Katharina Aschenbrenner, Maria Hinterberger, Elisabeth H Vollmann
Publikováno v:
Nature Immunology. 8:351-358
The parameters specifying whether autoreactive CD4(+) thymocytes are deleted (recessive tolerance) or differentiate into regulatory T cells (dominant tolerance) remain unresolved. Dendritic cells directly delete thymocytes, partly through cross-prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22135722239d46ba26ce62178940d3b4
https://doi.org/10.1038/ni1444
https://doi.org/10.1038/ni1444
Publikováno v:
International Congress Series. 1285:192-201
Autoimmune diseases present a significant health challenge. Animal models of autoimmunity have shed great insight into both disease pathogenesis as well as into the workings of the immune system in general. Myocarditis is an autoimmune disease with e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac1f5e6abde709a9b4475c9e0aa9037e
https://doi.org/10.1016/j.ics.2005.09.008
https://doi.org/10.1016/j.ics.2005.09.008
Publikováno v:
Immunity. (3):325-342
Dendritic cells (DCs) are critical for adaptive immunity and tolerance. Most DCs are strategically positioned as immune sentinels poised to respond to invading pathogens in tissues throughout the body. Differentiated DCs and their precursors also cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99e17d0c472ef0ee6e8f75ff87e8fdd