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pro vyhledávání: '"Elisabeth Hühner"'
Publikováno v:
Organic Letters. 21:498-502
Nonribosomal peptide synthetase (NRPS)-like enzymes comprising A-T-TE architectures catalyze the dimerization of α-keto carboxylic acids leading to the formation of hydroxybenzoquinones or lactones. Domain change experiments with five enzymes reveal
Publikováno v:
Applied microbiology and biotechnology. 102(4)
Non-ribosomal peptide synthetases (NRPSs) are key enzymes in microorganisms for the assembly of peptide backbones of biologically and pharmacologically active natural products. The monomodular NRPS-like enzymes comprise often an adenylation (A), a th