Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elisabeth G Rens"'
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 12, p e1007459 (2019)
Single and collective cell dynamics, cell shape changes, and cell migration can be conveniently represented by the Cellular Potts Model, a computational platform based on minimization of a Hamiltonian. Using the fact that a force field is easily deri
Externí odkaz:
https://doaj.org/article/d5e6f1d111bc4273b20d27974db71635
Mechanical cell-matrix feedback explains pairwise and collective endothelial cell behavior in vitro.
Autor:
René F M van Oers, Elisabeth G Rens, Danielle J LaValley, Cynthia A Reinhart-King, Roeland M H Merks
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 8, p e1003774 (2014)
In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells during vasculogenesis and angiogenesis. When seeded in an extracellular matrix, endothelial cells can form blood vessel-like structu
Externí odkaz:
https://doaj.org/article/a3b0a727f09e482c8661e4f06e080b92
Cell Shape and Durotaxis Explained from Cell-Extracellular Matrix Forces and Focal Adhesion Dynamics
Autor:
Elisabeth G. Rens, Roeland M.H. Merks
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101488- (2020)
Summary: Many cells are small and rounded on soft extracellular matrices (ECM), elongated on stiffer ECMs, and flattened on hard ECMs. Cells also migrate up stiffness gradients (durotaxis). Using a hybrid cellular Potts and finite-element model exten
Externí odkaz:
https://doaj.org/article/7320d86d53ba4c93929350aa2603fbce
Autor:
Adrian Danescu, Joy M. Richman, Katherine Fu, Leah Edelstein-Keshet, Elisabeth G. Rens, Takashi Akazawa, Johnathan Woo, Jaspreet Rehki
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
In the face, symmetry is established when bilateral streams of neural crest cells leave the neural tube at the same time, follow identical migration routes and then give rise to the facial prominences. However, developmental instability exists, parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c64a62bdba24f481eb10cb335899f29
http://europepmc.org/articles/PMC8126411
http://europepmc.org/articles/PMC8126411
Publikováno v:
Journal of Mathematical Biology, 82(4)
The polarization and motility of eukaryotic cells depends on assembly and contraction of the actin cytoskeleton and its regulation by proteins called GTPases. The activity of GTPases causes assembly of filamentous actin (by GTPases Cdc42, Rac), resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045b7e7142f417d5dfcf1f62529b7710
https://doi.org/10.1007/s00285-021-01550-0
https://doi.org/10.1007/s00285-021-01550-0
Publikováno v:
Physical biology, 18(6)
The small GTPases Rac and Rho are known to regulate eukaryotic cell shape, promoting front protrusion (Rac) or rear retraction (Rho) of the cell edge. Such cell deformation changes the contact and adhesion of cell to the extracellular matrix (ECM), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184826c274d2eb4438e62f59c5162565
http://resolver.tudelft.nl/uuid:61197e38-ea50-4939-b71d-31d60bda4b76
http://resolver.tudelft.nl/uuid:61197e38-ea50-4939-b71d-31d60bda4b76
Publikováno v:
Philosophical Transactions of the Royal Society of London Series B: Biological Sciences, 375(1807). The Royal Society
Philosophical Transactions of the Royal Society B, 375(1807)
Philos Trans R Soc Lond B Biol Sci
Philosophical Transactions of the Royal Society B, 375(1807)
Philos Trans R Soc Lond B Biol Sci
Epithelial branching morphogenesis drives the development of organs such as the lung, salivary gland, kidney and the mammary gland. It involves cell proliferation, cell differentiation and cell migration. An elaborate network of chemical and mechanic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069e1e6a73754bbf0dd3c69a82f1e011
http://hdl.handle.net/1887/3238969
http://hdl.handle.net/1887/3238969
Epithelial branching morphogenesis drives the development of organs such as the lung, salivary gland, kidney and the mammary gland. It involves cell proliferation, cell differentiation and cell migration. An elaborate network of chemical and mechanic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72cd0b55a2ad5804cc5d05be60da5c4a
https://doi.org/10.1101/2020.05.15.088377
https://doi.org/10.1101/2020.05.15.088377
Autor:
Elisabeth G. Rens, Roeland M. H. Merks
Publikováno v:
SSRN Electronic Journal.
Many animal cells change their shape depending on the stiffness of the substrate on which they are cultured: they assume small, rounded shapes in soft ECMs, they elongate within stiffer ECMs, and flatten out on hard substrates. Cells tend to prefer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edea0442fad45f93a3dd16be203f445e
https://doi.org/10.2139/ssrn.3569534
https://doi.org/10.2139/ssrn.3569534
Publikováno v:
Development, Growth and Differentiation
Development, Growth and Differentiation, 55, 390
Development Growth and Differentiation, 59(5), 329-339
Development, Growth and Differentiation, 55, 390
Development Growth and Differentiation, 59(5), 329-339
Mathematical modeling is an essential approach for the understanding of complex multicellular behaviors in tis- sue morphogenesis. Here, we review the cellular Potts model (CPM; also known as the Glazier-Graner-Hoge- weg model), an effective computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc667ee8894bd918f16a8d24a2fa6d4
https://doi.org/10.1111/dgd.12358
https://doi.org/10.1111/dgd.12358