Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Elisabeth Fischer‐Friedrich"'
Publikováno v:
Advanced Physics Research, Vol 3, Iss 12, Pp n/a-n/a (2024)
Abstract Epithelia are polarized layers of cells that line the outer and inner surfaces of organs. At the basal side, the epithelial cell layer is supported by a basement membrane, which is a thin polymeric layer of self‐assembled extracellular mat
Externí odkaz:
https://doaj.org/article/224c8adce494432396129b27d508f566
Autor:
Valentin Ruffine, Andreas Hartmann, Annika Frenzel, Michael Schlierf, Elisabeth Fischer‐Friedrich
Publikováno v:
Advanced Physics Research, Vol 2, Iss 12, Pp n/a-n/a (2023)
Abstract The actin cortex is an active polymer network underneath the plasma membrane at the periphery of mammalian cells. It is a major regulator of cell shape through the generation of active cortical tension. In addition, the cortex constitutes a
Externí odkaz:
https://doaj.org/article/f70e73e9f57b4c28aaead8603f3ea3bc
Publikováno v:
Advanced Science, Vol 7, Iss 19, Pp n/a-n/a (2020)
Abstract To undergo mitosis successfully, most animal cells need to acquire a round shape to provide space for the mitotic spindle. This mitotic rounding relies on mechanical deformation of surrounding tissue and is driven by forces emanating from ac
Externí odkaz:
https://doaj.org/article/754ab5e237d9407da23a23a1807bd9aa
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 12, p e1003347 (2013)
The rod-shaped bacterium Escherichia coli selects the cell center as site of division with the help of the proteins MinC, MinD, and MinE. This protein system collectively oscillates between the two cell poles by alternately binding to the membrane in
Externí odkaz:
https://doaj.org/article/d75ccc7d954948e6ac0f62ae619df82d
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 6, p e1002544 (2012)
Contractile function of striated muscle cells depends crucially on the almost crystalline order of actin and myosin filaments in myofibrils, but the physical mechanisms that lead to myofibril assembly remains ill-defined. Passive diffusive sorting of
Externí odkaz:
https://doaj.org/article/db37e5ab516146b98be0ffb91d68f084
Epithelial-mesenchymal transition (EMT) is a key cellular transformation for many physiological and pathological processes ranging from cancer over wound healing to embryogenesis. Changes in cell migration, cell morphology and cellular contractility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd36439d0974ce4881536940942b16b
https://doi.org/10.1101/2023.02.02.526815
https://doi.org/10.1101/2023.02.02.526815
Publikováno v:
Soft Matter. 18:2585-2596
Skin cancer is the most commonly occurring cancer in the USA and Germany, and the fourth most common cancer worldwide. Snail-dependent epithelial-mesenchymal transition (EMT) was shown to initiate and promote skin cancer. Previous studies could show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b1c107ec685bca0457bd26cd751fdc
https://doi.org/10.1039/d2sm00159d
https://doi.org/10.1039/d2sm00159d
The shaping of epithelial tissues into functional organs often depend on asymmetries in mechanical tension present at the apical and basal sides of cells. Contraction of an actomyosin meshwork underlying the apical side of cells is known to generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61f177c5b2c864e77a99ad9c97e9195f
https://doi.org/10.1101/2022.09.02.506324
https://doi.org/10.1101/2022.09.02.506324
Publikováno v:
Development. 149
The basement membrane is a specialized extracellular matrix (ECM) that is crucial for the development of epithelial tissues and organs. In Drosophila, the mechanical properties of the basement membrane play an important role in the proper elongation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b08152c4895a76d1add83f2eff91ad
https://doi.org/10.1242/dev.200456
https://doi.org/10.1242/dev.200456
Publikováno v:
Biophys J
Mechanosensation of cells is an important prerequisite for cellular function, e.g., in the context of cell migration, tissue organization, and morphogenesis. An important mechanochemical transducer is the actin cytoskeleton. In fact, previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a64736705bb06869afaafb471837d15
https://doi.org/10.1016/j.bpj.2020.07.031
https://doi.org/10.1016/j.bpj.2020.07.031