Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Elisabeth F. Gröne"'
Autor:
Hermann-Josef Gröne, Jana Löwen, Felix Bestvater, Wilhelm Kriz, Marie-Luise Groß-Weißmann, Elisabeth F. Gröne
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F600-F616
Based on analysis of 819 human biopsies, essential derangement in diabetic nephropathy consists of accumulation of worn-out glomerular basement membrane in the mesangium that may advance to global sclerosis. The most frequent pathway to nephron dropo
Publikováno v:
American Journal of Physiology-Renal Physiology. 317:F399-F410
As shown in our previous paper (Kriz W, Löwen J, Federico G, van den Born J, Gröne E, Gröne HJ. Am J Physiol Renal Physiol 312: F1101–F1111, 2017), mesangial matrix expansion in diabetic nephropathy (DN) results for a major part from the accumul
Autor:
Daniel M. Breitkopf, Klaus Tenbrock, Jürgen Floege, Juliane Hermann, Vera Jankowski, Xiyang Liu, Ute Raffetseder, Ina V. Martin, Elisabeth F. Gröne, Fabian Groll, Jialin Wang, Daniela Hermert, Kim Ohl, Thomas Rauen, Tammo Ostendorf
Publikováno v:
Kidney international. 97(2)
Systemic lupus erythematosus (SLE) is an autoimmune disease and lupus nephritis is a major risk factor for morbidity and mortality. Notch-3 signaling induced by membrane-bound or soluble ligands such as YB-1 constitutes an evolutionarily conserved pa
Autor:
Christina Alidousty, Daniela Hermert, Lydia Gibbert, Tammo Ostendorf, Matthias A. Neusser, Iris Macheleidt, Jürgen Floege, Daniel M. Breitkopf, Gerald S. Braun, Ute Raffetseder, Clemens D. Cohen, Thomas Rauen, Jialin Wang, Elisabeth F. Gröne
Publikováno v:
Clinical immunology (Orlando, Fla.). 194
Calcineurin inhibitors (CNIs) are a cornerstone of the current treatment in solid organ transplantation and autoimmune disease. However, CNIs also bear deleterious effects as they cause glomerular and tubulointerstitial fibrosis in the kidney. We rec
Autor:
Florina Olaru, Marc Schmitz, Stephanie Oehrl, Knut Schäkel, Hermann-J. Gröne, Michael Maas, Elisabeth F. Gröne, Alexander Enk, Thomas Döbel, Anke S. Lonsdorf
Lupus nephritis is a major cause of morbidity in patients with systemic lupus erythematosus. Among the different types of lupus nephritis, intracapillary immune complex (IC) deposition and accumulation of monocytes are hallmarks of lupus nephritis cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3b9fd71d2bb3cf85c182318f47890c
https://europepmc.org/articles/PMC6124405/
https://europepmc.org/articles/PMC6124405/
Publikováno v:
Journal of Inflammation (London, England)
Background Statins (HMG CoA reductase inhibitors), in addition to reducing circulating cholesterol and incidence of coronary heart disease, also have pleiotropic, anti-inflammatory effects. Patients with chronic liver diseases, non-alcoholic fatty li
Autor:
Jacob van den Born, Jana Löwen, Wilhelm Kriz, Elisabeth F. Gröne, Giuseppina Federico, Hermann Josef Gröne
Publikováno v:
American journal of physiology-Renal physiology, 312(6), F1101-F1111. AMER PHYSIOLOGICAL SOC
Thickening of the glomerular basement membrane (GBM) and expansion of the mesangial matrix are hallmarks of diabetic nephropathy (DN), generally considered to emerge from different sites of overproduction: GBM components from podocytes and mesangial
Autor:
Nicholas Obermüller, Johannes Müthing, Stefan Büttner, Giuseppina Federico, Richard Jennemann, Norbert Gretz, Ingeborg A. Hauser, Christoph Betz, Oliver Jung, Helmut Geiger, Hermann Josef Gröne, Elisabeth F. Gröne, Stefan Porubsky
Publikováno v:
The Journal of Pathology
The pathogenesis and therapy of Shigatoxin 2 (Stx2)-mediated kidney failure remain controversial. Our aim was to test whether, during an infection with Stx2-producing E. coli (STEC), Stx2 exerts direct effects on renal tubular epithelium and thereby
Publikováno v:
Der Nephrologe. 8:474-482
Dieser Artikel beschreibt die histopathologischen Veranderungen bei Lupusglomerulonephritis unter Einschluss von Differenzialdiagnosen. Die Lupusnephritis ist hauptsachlich eine Erkrankung des Glomerulus; pra- und postglomerulare Gefase und das Inter
Autor:
Bettina Kränzlin, Eva Kiss, Daniel Teupser, Joachim Thiery, Mahnaz Bonrouhi, Elisabeth F. Gröne, Norbert Gretz, Viola Nordström, Ernst Malle, Katja Wagenblaβ, Hermann Josef Gröne
Publikováno v:
The American Journal of Pathology. 182:727-741
Dyslipidemia is a frequent component of the metabolic disorder of diabetic patients contributing to organ damage. Herein, in low-density lipoprotein receptor–deficient hyperlipidemic and streptozotozin-induced diabetic mice, hyperglycemia and hyper