Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Elisabeth E. Kenngott"'
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Akademický článek
Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels.
Autor: Ralf Watzlawick, Elisabeth E Kenngott, Francesca Diane M Liu, Jan M Schwab, Alf Hamann
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137651 (2015)
Rapid activation of the innate immune system is critical for an efficient host response to invading pathogens. However, the inflammatory reaction has to be strictly controlled to minimize harmful immunopathology. A number of mediators including the c
Externí odkaz: https://doaj.org/article/5ea008dfa8cc4c2a995442eea336d372
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2
Akademický článek
Timed action of IL-27 protects from immunopathology while preserving defense in influenza.
Autor: Francesca Diane M Liu, Elisabeth E Kenngott, Micha F Schröter, Anja Kühl, Silke Jennrich, Ralf Watzlawick, Ute Hoffmann, Thorsten Wolff, Stephen Norley, Alexander Scheffold, Jason S Stumhofer, Christiaan J M Saris, Jan M Schwab, Christopher A Hunter, Gudrun F Debes, Alf Hamann
Publikováno v: PLoS Pathogens, Vol 10, Iss 5, p e1004110 (2014)
Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct therapies for this disease. H
Externí odkaz: https://doaj.org/article/f46c7abf103043808e7e70a88af3992e
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3
FRI0360 ANALYSIS OF BLOOD MONOCYTE TRANSCRIPTOMES AND BONE MARROW SAMPLES OF PATIENTS WITH AXIAL SPONDYLOARTHRITIS REVEALS THEIR CHANGES RELATED TO ACTIVATION AND MYELOPOIESIS
Autor: Andreas Grützkau, Ulrike Erben, Denis Poddubnyy, Joachim R. Grün, Elisabeth E. Kenngott, Fabian Karow, Biljana Smiljanovic, Uta Syrbe, Thomas Häupl
Publikováno v: Spondyloarthritis – etiology, pathogenesis and animal models.
Background Axial spondyloarthritis (axSpA) is characterized by inflammation within the axial skeleton. Previously, we observed preactivation of circulating monocytes of axSpA patients suggesting systemic immune activation apart from local skeletal in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::356ff47f3f7cb9f499c9aa01d9bb8ac1
https://doi.org/10.1136/annrheumdis-2019-eular.8051
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4
Identification of Targeting Peptides for Mucosal Delivery in Sheep and Mice
Autor: David R. Maass, Charles B. Shoemaker, Jennifer Pfeil, Alf Hamann, Wayne R. Hein, Rudolf Volkmer, Ute Hoffmann, L G Moore, A. Pernthaner, Sally Cole, Sarah M. Rosanowski, Uta Lauer, Saleh Umair, Elisabeth E. Kenngott
Publikováno v: Molecular Pharmaceutics. 13:202-210
In this study we identified and characterized a novel cyclic peptide that facilitates the rapid transportation of conjugated molecules across the epithelial layer of the small intestine. The peptide was initially selected from phage display libraries
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af66e198ff01fae6026f48f86424dfbb
https://doi.org/10.1021/acs.molpharmaceut.5b00635
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5
Synovial cell production of IL-26 induces bone mineralization in spondyloarthritis
Autor: Elisabeth E. Kenngott, Malene Hvid, Tue Wenzel Kragstrup, Bent Deleuran, Joachim Sieper, Anders Woetmann, Line Dam Heftdal, Ditte Jæhger, Uta Syrbe, René Østgård, Thomas Levin Andersen
Publikováno v: Heftdal, L D, Andersen, T, Jæhger, D, Woetmann, A, Østgård, R, Kenngott, E E, Syrbe, U, Sieper, J, Hvid, M, Deleuran, B & Kragstrup, T W 2017, ' Synovial cell production of IL-26 induces bone mineralization in spondyloarthritis ', Journal of Molecular Medicine, vol. 95, no. 7, pp. 779-787 . https://doi.org/10.1007/s00109-017-1528-2
Spondyloarthritis (SpA) is characterized by inflammation and new bone formation and can be treated by inhibition of the proinflammatory cytokines TNF-α and IL-17A. IL-26 is considered a proinflammatory cytokine, predominantly related to Th17 cells.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867ee2da038d1cbc891246a6afa58353
https://pure.au.dk/portal/da/publications/synovial-cell-production-of-il26-induces-bone-mineralization-in-spondyloarthritis(665f88be-2e60-4128-9eaf-8c0b4118fd40).html
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6
FRI0425 Analysis of cellular composition and cytokine expression in the subchondral bone marrow in ankylosing spondylitis
Autor: J. Sieper, R. Maier, J. Bleil, Uta Syrbe, Elisabeth E. Kenngott
Publikováno v: Poster Presentations.
Background Ankylosing spondylitis (AS) is characterized by inflammation within the sacroiliac joints and at the spine including vertebral bodies and facet joints. In AS, bone destruction is followed by new bone formation leading to ankylosis of joint
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1461ed35888e829b421048a55f15a22a
https://doi.org/10.1136/annrheumdis-2017-eular.3173
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7
Facilitated Peptide Transport via the Mucosal Epithelium: Impact on Tolerance Induction
Autor: A. Pernthaner, Jennifer Pfeil, Ute Hoffmann, Anne Rigby, Anja A. Kühl, Alf Hamann, Uta Lauer, Elisabeth E. Kenngott
Publikováno v: Frontiers in Immunology
A hallmark of autoimmunity is the breakdown of tolerance and generation of effector responses against self-antigens. A hallmark of autoimmunity is the breakdown of tolerance and generation of effector responses against self-antigens. Re-establishment
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bf11d7ad3681e1dad91aad1476374a
http://europepmc.org/articles/PMC5337492
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8
Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels
Autor: Alf Hamann, Ralf Watzlawick, Elisabeth E. Kenngott, Jan M. Schwab, Francesca Diane M. Liu
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137651 (2015)
PLoS ONE
Rapid activation of the innate immune system is critical for an efficient host response to invading pathogens. However, the inflammatory reaction has to be strictly controlled to minimize harmful immunopathology. A number of mediators including the c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b9bc327d0e5ea7fd02eca6bf0286af
http://europepmc.org/articles/PMC4567321?pdf=render
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10
Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza
Autor: Thorsten Wolff, Jan M. Schwab, Francesca Diane M. Liu, Christopher A. Hunter, Ralf Watzlawick, Anja A. Kühl, Silke Jennrich, Alf Hamann, Christiaan J. M. Saris, Gudrun F. Debes, Micha F. Schröter, Alexander Scheffold, Jason S. Stumhofer, Elisabeth E. Kenngott, Ute Hoffmann, Stephen Norley
Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 10, Iss 5, p e1004110 (2014)
Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct therapies for this disease. H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635247c0b25d81fe6048775cc4c8f45d
https://doi.org/10.1371/journal.ppat.1004110
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