Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elisabeth Dinter"'
Autor:
Maike R. Pollmanns, Judith Beer, Ines Rosignol, Natalia Rodriguez-Muela, Björn H. Falkenburger, Elisabeth Dinter
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Background: Protein aggregates are degraded via the autophagy-lysosome pathway and alterations in the lysosomal system leading to the accumulation of pathogenic proteins, including aggregates of α-synuclein in Parkinson’s disease (PD). The importa
Externí odkaz:
https://doaj.org/article/b4e37ee157ba41abb42096ec666f1feb
Autor:
Elisabeth Dinter, Theodora Saridaki, Leonie Diederichs, Heinz Reichmann, Björn H. Falkenburger
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-11 (2020)
Abstract Parkinson’s disease (PD) is diagnosed when patients exhibit bradykinesia with tremor and/or rigidity, and when these symptoms respond to dopaminergic medications. Yet in the last years there was a greater recognition of additional aspects
Externí odkaz:
https://doaj.org/article/344ea47ebac047bf8cda54261c922b4b
Autor:
Bengisu Turgutalp, Prabesh Bhattarai, Tugba Ercetin, Chiara Luise, Rengin Reis, Enise Ece Gurdal, Andreas Isaak, Derya Biriken, Elisabeth Dinter, Hande Sipahi, Dirk Schepmann, Anna Junker, Bernhard Wünsch, Wolfgang Sippl, Hayrettin Ozan Gulcan, Caghan Kizil, Mine Yarim
Publikováno v:
Journal of Medicinal Chemistry. 66:1652-1652
Autor:
Bengisu Turgutalp, Prabesh Bhattarai, Tugba Ercetin, Chiara Luise, Rengin Reis, Enise Ece Gurdal, Andreas Isaak, Derya Biriken, Elisabeth Dinter, Hande Sipahi, Dirk Schepmann, Anna Junker, Bernhard Wünsch, Wolfgang Sippl, Hayrettin Ozan Gulcan, Caghan Kizil, Mine Yarim
Publikováno v:
Journal of medicinal chemistry 65(18), 12292-12318 (2022). doi:10.1021/acs.jmedchem.2c01003
Drug development efforts that focused on single targets failed to provide effective treatment for Alzheimer's disease (AD). Therefore, we designed cholinesterase inhibition (ChEI)-based multi-target-directed ligands (MTDLs) to simultaneously target A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6057ebad29bc8504947e10ded5d4ded1
Autor:
Elisabeth Dinter, Diana Cozma, Björn H. Falkenburger, Theodora Saridaki, Eva M. Szegö, Anna Maria Hilverling
Publikováno v:
Cellular and Molecular Neurobiology
Cellular and molecular neurobiology 42(1), 155-171 (2022). doi:10.1007/s10571-021-01116-0
Cellular and molecular neurobiology 42, 155-171 (2022). doi:10.1007/s10571-021-01116-0
Cellular and molecular neurobiology 42(1), 155-171 (2022). doi:10.1007/s10571-021-01116-0
Cellular and molecular neurobiology 42, 155-171 (2022). doi:10.1007/s10571-021-01116-0
Cellular and molecular neurobiology 42, 155-171 (2022). doi:10.1007/s10571-021-01116-0
Published by Springer Science + Business Media B.V, Dordrecht
Published by Springer Science + Business Media B.V, Dordrecht
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b5010f448c6f241c94a7823fe27b1c
Publikováno v:
Parkinsonism & Related Disorders. 79:e3
Autor:
Theodora Saridaki, Aaron Voigt, Björn H. Falkenburger, Elisabeth Dinter, Katrin Marcus, Sarah Plum, Caroline May, Jörg B. Schulz, Leonie Diederichs, Daniel Komnig, Markus Nippold, Luisa Fensky
Publikováno v:
Journal of Neurochemistry. 138:758-774
Parkinson's disease can be caused by mutations in the α-synuclein gene and is characterized by aggregates of α-synuclein protein. Aggregates are degraded by the autophago-lysosomal pathway. Since Rab7 has been shown to regulate trafficking of late
Publikováno v:
Journal of Neurochemistry. 139:121-130
Developing new therapeutic strategies for Parkinson's disease requires cellular models. Current models reproduce the two most salient changes found in the brains of patients with Parkinson's disease: The degeneration of dopaminergic neurons and the e
Autor:
Theodora Saridaki, Markus Nippold, Leonie Diederichs, Elisabeth Dinter, Andreas Roos, Luisa Fensky, Björn H. Falkenburger, Jörg B. Schulz
Publikováno v:
Journal of neurochemistry. 146(4)
Parkinson's disease can be caused by mutations in the α-synuclein gene and is characterized by aggregates of α-synuclein protein. We have previously shown that over-expression of the small GTPase Rab7 can induce clearance of α-synuclein aggregates
Autor:
Theodora Saridaki, Elisabeth Dinter, Björn H. Falkenburger, Luisa Fensky, Leonie Diederichs, Markus Nippold, Andreas Roos
Publikováno v:
Basal Ganglia. 8:6-7