Zobrazeno 1 - 10
of 519
pro vyhledávání: '"Elisabeth B. Binder"'
Autor:
Linda Dieckmann, Marius Lahti-Pulkkinen, Cristiana Cruceanu, Katri Räikkönen, Elisabeth B. Binder, Darina Czamara
Publikováno v:
HGG Advances, Vol 5, Iss 4, Pp 100326- (2024)
Summary: The placenta, a pivotal player in the prenatal environment, holds crucial insights into early developmental pathways and future health outcomes. In this study, we explored genetic molecular regulation in chorionic villus samples (CVS) from t
Externí odkaz:
https://doaj.org/article/9e597dc0ae474854badf7ce27ab81315
Autor:
Lara Andreoli, Catalina Berca, Sonja Katz, Maryna Korshevniuk, Ritchie M. Head, Kristel Van Steen, TranSYS Consortium, Kris Dierickx, Federico Melograna, Zuqi Li, Giada Lalli, Johan M. Kros, Shiva Najjary, Damjana Rozman, Andrew Walakira, Alexander Skupin, Elle Wilson, Francisco X. Real, Benno Schwikowski, Behnam Yousefi, Nataša Pržulj, Katarina Mihajlovic, Elisabeth B. Binder, Nahid Taheri, Anastasiia Hryhorzhevska, Lude Franke, George P. Patrinos, Kariofyllis Karamperis, Oscar Lao, Vitor A. P. Martins dos Santos, Christina Olsen, Ritchie Head
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionIn the evolving healthcare landscape, precision medicine's rise necessitates adaptable doctoral training. The European Union has recognized this and promotes the development of international, training-focused programmes called Innovative
Externí odkaz:
https://doaj.org/article/33e1667ff3424246bdd333e44becb2c0
Autor:
Anne Kühnel, Jonas Hagenberg, Janine Knauer-Arloth, Maik Ködel, Michael Czisch, Philipp G. Sämann, BeCOME working group, Elisabeth B. Binder, Nils B. Kroemer
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Overweight and obesity are associated with altered stress reactivity and increased inflammation. However, it is not known whether stress-induced changes in brain function scale with BMI and if such associations are driven by peripheral cytok
Externí odkaz:
https://doaj.org/article/388622722850454a9a61965de0ed01bd
Autor:
John M. Felt, Natan Yusupov, Karra D. Harrington, Julia Fietz, Zhenyu “Zach” Zhang, Martin J. Sliwinski, Nilam Ram, Kieran J. O'Donnell, Michael J. Meaney, Frank W. Putnam, Jennie G. Noll, Elisabeth B. Binder, Chad E. Shenk
Publikováno v:
Neurobiology of Stress, Vol 27, Iss , Pp 100577- (2023)
Background: Early life adversity and psychiatric disorders are associated with earlier declines in neurocognitive abilities during adulthood. These declines may be preceded by changes in biological aging, specifically epigenetic age acceleration, pro
Externí odkaz:
https://doaj.org/article/ec2246409a054cfcbe9848a223d14f97
Autor:
Nora L. Großmann, Antoine Weihs, Luise Kühn, Susann Sauer, Simone Röh, Tobias Wiechmann, Monika Rex-Haffner, Henry Völzke, Uwe Völker, Elisabeth B. Binder, Alexander Teumer, Georg Homuth, Johanna Klinger-König, Hans J. Grabe
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1485 (2024)
Childhood maltreatment is an important risk factor for adult depression and has been associated with changes in the hypothalamic pituitary adrenal (HPA) axis, including cortisol secretion and methylation of the FKBP5 gene. Furthermore, associations b
Externí odkaz:
https://doaj.org/article/a05adad339b94856bd3b86b447ffc67a
Autor:
Nicolas Rost, Tanja M. Brückl, Nikolaos Koutsouleris, Elisabeth B. Binder, Bertram Müller-Myhsok
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Predicting treatment outcome in major depressive disorder (MDD) remains an essential challenge for precision psychiatry. Clinical prediction models (CPMs) based on supervised machine learning have been a promising approach for thi
Externí odkaz:
https://doaj.org/article/934ed2ab88874117bdef5ed7a853e722
Autor:
Katherine Bassil, Anthi C. Krontira, Thomas Leroy, Alana I.H. Escoto, Clara Snijders, Cameron D. Pernia, R. Jeroen Pasterkamp, Laurence de Nijs, Daniel van den Hove, Gunter Kenis, Marco P. Boks, Krishna Vadodaria, Nikolaos P. Daskalakis, Elisabeth B. Binder, Bart P.F. Rutten
Publikováno v:
Neurobiology of Stress, Vol 23, Iss , Pp 100530- (2023)
Hypothalamic-pituitary adrenal (HPA)axis dysregulation has long been implicated in stress-related disorders such as major depression and post-traumatic stress disorder. Glucocorticoids (GCs) are released from the adrenal glands as a result of HPA-axi
Externí odkaz:
https://doaj.org/article/4a6b05cc3b3242c0859374839792ad82
Autor:
Oliver Pain, Karen Hodgson, Vassily Trubetskoy, Stephan Ripke, Victoria S. Marshe, Mark J. Adams, Enda M. Byrne, Adrian I. Campos, Tania Carrillo-Roa, Annamaria Cattaneo, Thomas D. Als, Daniel Souery, Mojca Z. Dernovsek, Chiara Fabbri, Caroline Hayward, Neven Henigsberg, Joanna Hauser, James L. Kennedy, Eric J. Lenze, Glyn Lewis, Daniel J. Müller, Nicholas G. Martin, Benoit H. Mulsant, Ole Mors, Nader Perroud, David J. Porteous, Miguel E. Rentería, Charles F. Reynolds, III, Marcella Rietschel, Rudolf Uher, Eleanor M. Wigmore, Wolfgang Maier, Naomi R. Wray, Katherine J. Aitchison, Volker Arolt, Bernhard T. Baune, Joanna M. Biernacka, Guido Bondolfi, Katharina Domschke, Masaki Kato, Qingqin S. Li, Yu-Li Liu, Alessandro Serretti, Shih-Jen Tsai, Gustavo Turecki, Richard Weinshilboum, Andrew M. McIntosh, Cathryn M. Lewis, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Manuel Mattheisen, Maciej Trzaskowski, Abdel Abdellaoui, Esben Agerbo, Tracy M. Air, Till F.M. Andlauer, Silviu-Alin Bacanu, Marie Bækvad-Hansen, Aartjan T.F. Beekman, Tim B. Bigdeli, Elisabeth B. Binder, Julien Bryois, Henriette N. Buttenschøn, Jonas Bybjerg-Grauholm, Na Cai, Enrique Castelao, Jane Hvarregaard Christensen, Toni-Kim Clarke, Jonathan R.I. Coleman, Lucía Colodro-Conde, Baptiste Couvy-Duchesne, Nick Craddock, Gregory E. Crawford, Gail Davies, Ian J. Deary, Franziska Degenhardt, Eske M. Derks, Nese Direk, Conor V. Dolan, Erin C. Dunn, Thalia C. Eley, Valentina Escott-Price, Farnush Farhadi Hassan Kiadeh, Hilary K. Finucane, Jerome C. Foo, Andreas J. Forstner, Josef Frank, Héléna A. Gaspar, Michael Gill, Fernando S. Goes, Scott D. Gordon, Jakob Grove, Lynsey S. Hall, Christine Søholm Hansen, Thomas F. Hansen, Stefan Herms, Ian B. Hickie, Per Hoffmann, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, David M. Hougaard, David M. Howard, Marcus Ising, Rick Jansen, Ian Jones, Lisa A. Jones, Eric Jorgenson, James A. Knowles, Isaac S. Kohane, Julia Kraft, Warren W. Kretzschmar, Zoltán Kutalik, Yihan Li, Penelope A. Lind, Donald J. MacIntyre, Dean F. MacKinnon, Robert M. Maier, Jonathan Marchini, Hamdi Mbarek, Patrick McGrath, Peter McGuffin, Sarah E. Medland, Divya Mehta, Christel M. Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Francis M. Mondimore, Grant W. Montgomery, Sara Mostafavi, Niamh Mullins, Matthias Nauck, Bernard Ng, Michel G. Nivard, Dale R. Nyholt, Paul F. O’Reilly, Hogni Oskarsson, Michael J. Owen, Jodie N. Painter, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Roseann E. Peterson, Wouter J. Peyrot, Giorgio Pistis, Danielle Posthuma, Jorge A. Quiroz, Per Qvist, John P. Rice, Brien P. Riley, Margarita Rivera, Saira Saeed Mirza, Robert Schoevers, Eva C. Schulte, Ling Shen, Jianxin Shi, Stanley I. Shyn, Engilbert Sigurdsson, Grant C.B. Sinnamon, Johannes H. Smit, Daniel J. Smith, Hreinn Stefansson, Stacy Steinberg, Fabian Streit, Jana Strohmaier, Katherine E. Tansey, Henning Teismann, Alexander Teumer, Wesley Thompson, Pippa A. Thomson, Thorgeir E. Thorgeirsson, Matthew Traylor, Jens Treutlein, André G. Uitterlinden, Daniel Umbricht, Sandra Van der Auwera, Albert M. van Hemert, Alexander Viktorin, Peter M. Visscher, Yunpeng Wang, Bradley T. Webb, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H. Witt, Yang Wu, Hualin S. Xi, Jian Yang, Futao Zhang, Klaus Berger, Dorret I. Boomsma, Sven Cichon, Udo Dannlowski, E.J.C. de Geus, J. Raymond DePaulo, Enrico Domenici, Tõnu Esko, Hans J. Grabe, Steven P. Hamilton, Andrew C. Heath, Kenneth S. Kendler, Stefan Kloiber, Susanne Lucae, Pamela A.F. Madden, Patrik K. Magnusson, Andres Metspalu, Preben Bo Mortensen, Bertram Müller-Myhsok, Merete Nordentoft, Markus M. Nöthen, Michael C. O’Donovan, Sara A. Paciga, Nancy L. Pedersen, Brenda W.J.H. Penninx, Roy H. Perlis, James B. Potash, Martin Preisig, Catherine Schaefer, Thomas G. Schulze, Jordan W. Smoller, Kari Stefansson, Henning Tiemeier, Henry Völzke, Myrna M. Weissman, Thomas Werge, Douglas F. Levinson, Gerome Breen, Anders D. Børglum, Patrick F. Sullivan
Publikováno v:
Biological Psychiatry Global Open Science, Vol 2, Iss 2, Pp 115-126 (2022)
Background: Antidepressants are a first-line treatment for depression. However, only a third of individuals experience remission after the first treatment. Common genetic variation, in part, likely regulates antidepressant response, yet the success o
Externí odkaz:
https://doaj.org/article/c97a14decdf44013b3e7f514e212f02f
Autor:
Sarah R. Moore, Thorhildur Halldorsdottir, Jade Martins, Susanne Lucae, Bertram Müller-Myhsok, Nikola S. Müller, Charlotte Piechaczek, Lisa Feldmann, Franz Joseph Freisleder, Ellen Greimel, Gerd Schulte-Körne, Elisabeth B. Binder, Janine Arloth
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Substantial sex differences have been reported in the physiological response to stress at multiple levels, including the release of the stress hormone, cortisol. Here, we explore the genomic variants in 93 females and 196 males regulating th
Externí odkaz:
https://doaj.org/article/25a1e6e27f9542168ff9b38cd47ed007
Autor:
Sarah Irmscher, Svante L. H. Zipfel, Luke D. Halder, Lia Ivanov, Andres Gonzalez-Delgado, Christoph Waldeyer, Moritz Seiffert, Fabian J. Brunner, Monika von der Heide, Ina Löschmann, Sonia Wulf, Darina Czamara, Nikolina Papac-Milicevic, Olaf Strauß, Stefan Lorkowski, Hermann Reichenspurner, Michael V. Holers, Nirmal K. Banda, Tania Zeller, Elisabeth B. Binder, Christoph J. Binder, Thorsten Wiech, Peter F. Zipfel, Christine Skerka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Atherosclerotic cardiovascular disease (ACVD) is a lipid-driven inflammatory disease and one of the leading causes of death worldwide. Lipid deposits in the arterial wall lead to the formation of plaques that involve lipid oxidation, cellula
Externí odkaz:
https://doaj.org/article/f4fef222f3624b56b6f873bb7fc7bb7a