Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elisabeth Bäck"'
Autor:
Mei Ding, Rajneesh Malhotra, Tomas Ottosson, Magnus Lundqvist, Aman Mebrahtu, Johan Brengdahl, Ulf Gehrmann, Elisabeth Bäck, Douglas Ross-Thriepland, Ida Isaksson, Björn Magnusson, Kris F. Sachsenmeier, Hanna Tegel, Sophia Hober, Mathias Uhlén, Lorenz M. Mayr, Rick Davies, Johan Rockberg, Lovisa Holmberg Schiavone
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Regulatory T cells (Tregs) are the key cells regulating peripheral autoreactive T lymphocytes. Tregs exert their function by suppressing effector T cells. Tregs have been shown to play essential roles in the control of a variety of physiolog
Externí odkaz:
https://doaj.org/article/3192eee1ef58427faaa5eafd5d5b98ec
Autor:
Elisabeth Bäck, Jörgen Östling, Mei Ding, Christopher McCrae, Christian Tyrchan, Steffen Schubert
Publikováno v:
SLAS Discovery. 25:634-645
Human rhinovirus (RV) is the most common cause of acute upper respiratory tract infections and has recently been shown to play a significant role in exacerbations of asthma and chronic obstructive pulmonary disease (COPD). There is a significant unme
Autor:
Roine I. Olsson, Rikard Pehrson, Rongfeng Chen, Jesper Malmberg, Anna Malmberg, Nafizal Hossain, Hanna Grindebacke, Mia Collins, Matti Lepistö, Yao Xiong, Nina Krutrök, Antonio Llinas, Thomas Hansson, Eva L. Hansson, Elisabeth Bäck, Anna Aagaard, Jane McPheat, Linda Thunberg, Sarah Lever, Agnes Leffler, Yafeng Xue, Stefan von Berg, Petter Svanberg, Frank Narjes, Marie Ramnegård, Glyn Hughes, Johan Jirholt
Publikováno v:
Journal of medicinal chemistry. 64(18)
Inverse agonists of the nuclear receptor RORC2 have been widely pursued as a potential treatment for a variety of autoimmune diseases. We have discovered a novel series of isoindoline-based inverse agonists of the nuclear receptor RORC2, derived from
Autor:
Tomas Ottosson, Rick Davies, Elisabeth Bäck, Lovisa Holmberg Schiavone, Mathias Uhlén, Johan Rockberg, Kris Sachsenmeier, Hanna Tegel, Mei Ding, Johan Brengdahl, Ulf Gehrmann, Lorenz M. Mayr, Björn Magnusson, Sophia Hober, Ida Isaksson, Rajneesh Malhotra, Aman Mebrahtu, Magnus Lundqvist, Douglas Ross-Thriepland
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Regulatory T cells (Tregs) are the key cells regulating peripheral autoreactive T lymphocytes. Tregs exert their function by suppressing effector T cells. Tregs have been shown to play essential roles in the control of a variety of physiological and
Autor:
Hanna Grindebacke, Frank Narjes, Eva L. Hansson, Yao Xiong, Antonio Llinas, Linda Thunberg, Jesper Malmberg, Stefan Tångefjord, Roine I. Olsson, Ge Hongbin, Rongfeng Chen, Yafeng Xue, Agnes Leffler, Hanna Leek, Thomas Hansson, Elisabeth Bäck, Jane McPheat, Nafizal Hossain, Matti Lepistö, Stefan von Berg, Johan Jirholt, Anna Aagaard
Publikováno v:
Journal of Medicinal Chemistry. 61:7796-7813
Retinoic acid receptor related orphan receptor γt (RORγt), has been identified as the master regulator of TH17-cell function and development, making it an attractive target for the treatment of autoimmune diseases by a small-molecule approach. Here
Autor:
Karin Kaspersson, Ian Gurrell, Elisabeth Bäck, Samantha Budd Haeberlein, Karin Kolmodin, Roland Bürli, Michael J. McKenzie, Susanna Eketjäll, Philip Thorne, Patrik Johansson, Jörg Holenz, Gvido Cebers, Clay W Scott, Mark E. Duggan, Paul R. J. Davey, Haydn Beaton
Publikováno v:
Journal of medicinal chemistry. 61(8)
BACE1 is responsible for the first step in APP proteolysis, leading to toxic Aβ production, and has been indicated to play a key role in the pathogenesis of Alzheimer's disease. The related isoform BACE2 is thought to be involved in processing of th
Publikováno v:
Nordisk Välfärdsforskning, Vol 7, Iss 1, Pp 23-35 (2022)
Licensing is a public instrument used to control welfare services. One such service is residential care for children, which is targeted at children who experience maltreatment in their home environment and/or have behavioural problems and have been s
Externí odkaz:
https://doaj.org/article/0766d192d38747558bc2f93a0466c5f9
Publikováno v:
Psychosocial Intervention, Vol 22, Iss 3, Pp 193-202 (2014)
An overview of the current situation in the out-of-home care in Norway and Sweden is presented in this article; also the development in later years is described and discussed. Socially, politically and culturallythere are few differences between Norw
Externí odkaz:
https://doaj.org/article/5ed044e5addf42c0873fd9c15e0a0bf0
Autor:
Aron Shlonsky, Kate Schumaker, Charlene Cook, David Crampton, Michael Saini, Elisabeth Backe‐Hansen, Krystyna Kowalski
Publikováno v:
Campbell Systematic Reviews, Vol 5, Iss 1, Pp 1-33 (2009)
Externí odkaz:
https://doaj.org/article/d52cd40dba1b4db39ca9666188712a2d
Publikováno v:
Tidsskrift for Ungdomsforskning, Vol 12, Iss 2 (2014)
Externí odkaz:
https://doaj.org/article/a0918c4981cb485990da439e883bc091