Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Elisabeth Öhler"'
Autor:
Elisabeth Öhler, Johann Mulzer
Publikováno v:
Angewandte Chemie. 113:3961-3964
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bfe3cf275f5bfad68d5682773afb13e
https://doi.org/10.1002/1521-3757(20011015)113:20<3961::aid-ange3961>3.0.co
https://doi.org/10.1002/1521-3757(20011015)113:20<3961::aid-ange3961>3.0.co
Autor:
Johann Mulzer, Elisabeth Öhler
Publikováno v:
Angewandte Chemie International Edition. 40:3842-3846
The microtubule-stabilizing antitumor agent laulimalide (1) has been obtained in by new synthetic route. The carbon skeleton was assembled by means of Julia-Kocienski (C16-C17) and Horner-Wadsworth-Emmons (C21-C22) olefinations. Still-Gennari olefina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba6b9e2618a2f03125cf321d0f71da0
https://doi.org/10.1002/1521-3773(20011015)40:20<3842::aid-anie3842>3.0.co
https://doi.org/10.1002/1521-3773(20011015)40:20<3842::aid-anie3842>3.0.co
Publikováno v:
Synthesis. 2001:2007-2010
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b4ab1ad96da273349587e683bce544
https://doi.org/10.1055/s-2001-17715
https://doi.org/10.1055/s-2001-17715
Publikováno v:
Synlett. 2001:1105-1108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6fd23fa9813da11baf5192f79f40d78
https://doi.org/10.1055/s-2001-15145
https://doi.org/10.1055/s-2001-15145
Publikováno v:
Tetrahedron Letters. 41:6323-6326
A stereocontrolled synthesis of the C15–C27 fragment of laulimalide is described. Key features are a divergent–convergent synthesis from (R)-glycidol, an interesting formation of a trisubstituted double bond via ring closing metathesis with Grubb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9ffe112a6433d3a06f587567f623223
https://doi.org/10.1016/s0040-4039(00)00961-8
https://doi.org/10.1016/s0040-4039(00)00961-8
Publikováno v:
Tetrahedron Letters. 39:8633-8636
An easy access to four out of five naturally occurring epothilones (A-E, 1–5 ) is reported. Key steps are an enantioselective Mukaiyama type aldol reaction, ( E )- and ( Z )-selective olefinations, and a sulfone alkylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ba1790d57564f1a0bff565ee60a8951
https://doi.org/10.1016/s0040-4039(98)02026-7
https://doi.org/10.1016/s0040-4039(98)02026-7
Publikováno v:
Tetrahedron Letters. 38:7725-7728
Compound 11, representing the C(11)C(20) segment of the macrolide epothilone B (1b) has been prepared using two Wittig reactions and a Sharpless asymmetric epoxidation as the key steps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301e325b99b163e1027925069d1acbc1
https://doi.org/10.1016/s0040-4039(97)10150-2
https://doi.org/10.1016/s0040-4039(97)10150-2
Autor:
Elisabeth Öhler, Silvia Kanzler
Publikováno v:
Liebigs Annalen. 1997:1437-1445
Palladium(0)-catalyzed allylic alkylation of diethyl (acetyl-amino)malonate (6), ethyl (diphenylmethyleneamino)acetate (7), and (diphenylmethyleneamino)acetonitrile (8), respectively, with the acrolein-derived 1-dialkoxyphosphinyl-substituted carbona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ac256935951b0bc9f952c91973212e9
https://doi.org/10.1002/jlac.199719970722
https://doi.org/10.1002/jlac.199719970722
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 128:183-190
Apioshowdomycin (3-(D-apio-β-D-furanosyl)-1H-pyrrole-2,5-dione,2) has been prepared as an analogue of the C-nucleoside showdomycin (1) in eight steps and with 5% overall yield, starting from 2,3-O-isopropylidene-D-apio-β-D-furanose (3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1e11158675f40df40e7ec350d497e2
https://doi.org/10.1007/bf00807307
https://doi.org/10.1007/bf00807307
Autor:
Friedrich Hammerschmidt, Andreas Schirbel, Elisabeth Öhler, Martina Stichelberger, Ilse Zolle, Stefanie Hahner, Michael L. Berger, Roger Schibli, Renzhe Qian, Vladimir B. Arion, Anna Woschek, Jie Yu
Publikováno v:
Molecular pharmaceutics. 10(3)
Metyrapone, metyrapol, and etomidate are competitive inhibitors of 11-deoxycorticosterone hydroxylation by 11β-hydroxylase. [(3)H]Metyrapol and 4-[(131)I]iodometomidate bind with high affinity to membranes prepared from bovine and rat adrenals. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558cfdae38a12241afd5676da916a284
https://pubmed.ncbi.nlm.nih.gov/23343186
https://pubmed.ncbi.nlm.nih.gov/23343186