Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elisabeth, Weyher"'
Autor:
Mahesh Lingaraju, Fabien Bonneau, Elisabeth Weyher, Yair Gat, Elena Conti, Jan M. Schuller, Michael A. Strauss, Peter J. Murray
Publikováno v:
Nature Structural & Molecular Biology. 26:1089-1093
We report the 3.45-A resolution cryo-EM structure of human SMG1-SMG8-SMG9, a phosphatidylinositol-3-kinase (PI(3)K)-related protein kinase (PIKK) complex central to messenger RNA surveillance. Structural and MS analyses reveal the presence of inosito
Autor:
Yair, Gat, Jan Michael, Schuller, Mahesh, Lingaraju, Elisabeth, Weyher, Fabien, Bonneau, Mike, Strauss, Peter J, Murray, Elena, Conti
Publikováno v:
Nature structuralmolecular biology. 26(12)
We report the 3.45-Å resolution cryo-EM structure of human SMG1-SMG8-SMG9, a phosphatidylinositol-3-kinase (PI(3)K)-related protein kinase (PIKK) complex central to messenger RNA surveillance. Structural and MS analyses reveal the presence of inosit
Autor:
Massimiliano Orsini, Wolfgang Baumeister, Luca Zinzula, Elisabeth Weyher-Stingl, Andreas Bracher, István Nagy
Publikováno v:
Structure (London, England : 1993). 27(1)
Summary The multifunctional virion protein 35 (VP35) of ebolaviruses is a critical determinant of virulence and pathogenesis indispensable for viral replication and host innate immune evasion. Essential for VP35 function is homo-oligomerization via a
Autor:
Nediljko Budisa, Waltraud Wenger, Marina Rubini, Robert Huber, Luis Moroder, Ralph Golbik, Jae Hyun Bae, Elisabeth Weyher
Publikováno v:
Angewandte Chemie International Edition. 41:4066-4069
Autor:
Elisabeth Weyher, Waltraud Wenger, Jae Hyun Bae, Nediljko Budisa, Ralph Golbik, Luis Moroder, Robert Huber, Marina Rubini
Publikováno v:
Angewandte Chemie. 114:4238-4242
Publikováno v:
European Journal of Biochemistry. 253:1-9
We have recently developed methods for specific and high-level replacement of methionine with 2-aminohexanoic acid, selenomethionine and telluromethionine as isosteric and atomic analogues for structural investigations of human recombinant annexin V.
Publikováno v:
Journal of Peptide Science. 2:271-275
A new method has been developed for the rapid determination of D-cysteine contents in synthetic peptides. It is based on the reduction of cystine residues, when present, with tris-alkylphosphines, selective derivatization of the cysteine residues wit
Publikováno v:
Journal of Peptide Science. 1:360-370
The fully active gastrin and CCK analogues [Nle 15]-gastrin-17 and [Nle, Thr]-CCK-9 were analysed for their Ca2+ and Tb3+ affinities in various membrane mimetic conditions. In TFE both gastrin and CCK exhibited high affinities for calcium and terbium
Autor:
István Nagy, Na Sun, Roland Wilhelm Knispel, Elisabeth Weyher-Stingl, Massimiliano Orsini, Sándor Varga, Stephan Nickell, Marius Boicu, Wolfgang Baumeister, Rubén Fernández-Busnadiego, Christine Kofler, József Kukolya
Publikováno v:
FEMS Microbiology Letters
Cytosolic, globular droplets with an average diameter of 50 nm were observed in vitrified Thermoplasma acidophilum cells by means of cryo-electron tomography. These droplets were isolated by column chromatography and immunoprecipitation protein purif
Publikováno v:
Biopolymers. 32:1545-1558
The (2RS) −1,2-dipalmitoyl−3-mercaptoglycerol/-, (2RS) −1,2-dimyristoy1–3-mercaptogly-cerol/−, and (2RS)-1-myristoy1–2-palmitoy1–3-mercaptoglycerol/maleoyl-β-alanyl-[Nle15]-human-gastrin-(2–17) adducts were prepared as lipo-gastrin d