Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Elisabeth, Werkmeister"'
Autor:
Anthony Lefebvre, Camille Trioën, Sarah Renaud, William Laine, Benjamin Hennart, Clément Bouchez, Bertrand Leroux, Delphine Allorge, Jérôme Kluza, Elisabeth Werkmeister, Guillaume Paul Grolez, Nadira Delhem, Olivier Moralès
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Nasopharyngeal carcinoma‐derived small extracellular vesicles (NPCSEVs) have an immunosuppressive impact on the tumour microenvironment. In this study, we investigated their influence on the generation of tolerogenic dendritic cells and th
Externí odkaz:
https://doaj.org/article/15bbc9120a924f3ab8aab4e6fc2461a7
Autor:
Alexandre Quilbe, Rami Mustapha, Belinda Duchêne, Abhishek Kumar, Elisabeth Werkmeister, Emmanuelle Leteurtre, Olivier Moralès, Nicolas Jonckheere, Isabelle Van Seuningen, Nadira Delhem
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPancreatic adenocarcinoma (PDAC) is a devastating disease with an urgent need for therapeutic innovation. Immune checkpoint inhibition has shown promise in a variety of solid tumors, but most clinical trials have failed to demonstrate clini
Externí odkaz:
https://doaj.org/article/b5d1cdad42af40cfbbd8dc03480fea9b
Autor:
Sandra Pérez-Domínguez, Elisabeth Werkmeister, Maria Luisa Marini, Vincent Dupres, Sébastien Janel, Frank Lafont, Manfred Radmacher
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/ec3b7260032649869c7b27e729ef5e4a
Autor:
Imène Belhaouane, Amine Pochet, Jonathan Chatagnon, Eik Hoffmann, Christophe J Queval, Nathalie Deboosère, Céline Boidin-Wichlacz, Laleh Majlessi, Valentin Sencio, Séverine Heumel, Alexandre Vandeputte, Elisabeth Werkmeister, Laurence Fievez, Fabrice Bureau, Yves Rouillé, François Trottein, Mathias Chamaillard, Priscille Brodin, Arnaud Machelart
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011192 (2023)
Progression of tuberculosis is tightly linked to a disordered immune balance, resulting in inability of the host to restrict intracellular bacterial replication and its subsequent dissemination. The immune response is mainly characterized by an orche
Externí odkaz:
https://doaj.org/article/b076df58fca44a32911ed45f8f9c632b
Autor:
Sandra Pérez-Domínguez, Elisabeth Werkmeister, Maria Luisa Marini, Vincent Dupres, Sébastien Janel, Frank Lafont, Manfred Radmacher
Publikováno v:
Frontiers in Physics, Vol 10 (2022)
In tissue, cells are obliged to confine and adapt to a specific geometric shape due to the surrounding environmental constraints. Under healthy conditions, fibroblasts present an elongated shape; however, changes in biochemical and physical propertie
Externí odkaz:
https://doaj.org/article/a663644cb3af402aaa1c66d25f6066e7
Autor:
Bernardo Cuffaro, Denise Boutillier, Jérémy Desramaut, Amin Jablaoui, Elisabeth Werkmeister, François Trottein, Anne-Judith Waligora-Dupriet, Moez Rhimi, Emmanuelle Maguin, Corinne Grangette
Publikováno v:
Cells, Vol 12, Iss 9, p 1260 (2023)
The gut microbiota is now considered as a key player in the development of metabolic dysfunction. Therefore, targeting gut microbiota dysbiosis has emerged as a new therapeutic strategy, notably through the use of live gut microbiota-derived biothera
Externí odkaz:
https://doaj.org/article/ac47b74fe05c4840960059406b871139
Autor:
Carole Trzaska, Séverine Amand, Christine Bailly, Catherine Leroy, Virginie Marchand, Evelyne Duvernois-Berthet, Jean-Michel Saliou, Hana Benhabiles, Elisabeth Werkmeister, Thierry Chassat, Romain Guilbert, David Hannebique, Anthony Mouray, Marie-Christine Copin, Pierre-Arthur Moreau, Eric Adriaenssens, Andreas Kulozik, Eric Westhof, David Tulasne, Yuri Motorin, Sylvie Rebuffat, Fabrice Lejeune
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nonsense mutations can be corrected by several molecules that activate readthrough of premature termination codon. Here, the authors report that 2,6-diaminopurine efficiently corrects UGA nonsense mutations with no significant toxicity.
Externí odkaz:
https://doaj.org/article/970f33637b174d7ca2db00d47c85ff08
Autor:
Kannan Venugopal, Sylia Chehade, Elisabeth Werkmeister, Nicolas Barois, Javier Periz, Frank Lafont, Isabelle Tardieux, Jamal Khalife, Gordon Langsley, Markus Meissner, Sabrina Marion
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008106 (2020)
Toxoplasma gondii possesses an armada of secreted virulent factors that enable parasite invasion and survival into host cells. These factors are contained in specific secretory organelles, the rhoptries, micronemes and dense granules that release the
Externí odkaz:
https://doaj.org/article/a239896d92e9456983b20a04c3aed2a7
Autor:
Florent Letronne, Geoffroy Laumet, Anne-Marie Ayral, Julien Chapuis, Florie Demiautte, Mathias Laga, Michel E. Vandenberghe, Nicolas Malmanche, Florence Leroux, Fanny Eysert, Yoann Sottejeau, Linda Chami, Amandine Flaig, Charlotte Bauer, Pierre Dourlen, Marie Lesaffre, Charlotte Delay, Ludovic Huot, Julie Dumont, Elisabeth Werkmeister, Franck Lafont, Tiago Mendes, Franck Hansmannel, Bart Dermaut, Benoit Deprez, Anne-Sophie Hérard, Marc Dhenain, Nicolas Souedet, Florence Pasquier, David Tulasne, Claudine Berr, Jean-Jacques Hauw, Yves Lemoine, Philippe Amouyel, David Mann, Rebecca Déprez, Frédéric Checler, David Hot, Thierry Delzescaux, Kris Gevaert, Jean-Charles Lambert
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 278-292 (2016)
Although several ADAMs (A disintegrin-like and metalloproteases) have been shown to contribute to the amyloid precursor protein (APP) metabolism, the full spectrum of metalloproteases involved in this metabolism remains to be established. Transcripto
Externí odkaz:
https://doaj.org/article/b6a220c6a95c4d56a4492c3f25a412a8
Autor:
Lamba Omar Sangaré, Tchilabalo Dilezitoko Alayi, Benoit Westermann, Agnes Hovasse, Fabien Sindikubwabo, Isabelle Callebaut, Elisabeth Werkmeister, Frank Lafont, Christian Slomianny, Mohamed-Ali Hakimi, Alain Van Dorsselaer, Christine Schaeffer-Reiss, Stanislas Tomavo
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of
Externí odkaz:
https://doaj.org/article/2b4b0e9f9cbe44d0921cbc4be51f84a4