Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Elisabeth, Schültke"'
Autor:
Yikun Mei, Elena Lakotsenina, Marie Wegner, Timon Hehne, Dieter Krause, Dani Hakimeh, Dongwei Wu, Elisabeth Schültke, Franziska Hausmann, Jens Kurreck, Beatrice Tolksdorf
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10268 (2024)
Lung cancer continues to have one of the highest morbidity and mortality rates of any cancer. Although radiochemotherapy, in combination with immunotherapy, has significantly improved overall survival, new treatment options are urgently needed. Howev
Externí odkaz:
https://doaj.org/article/d66dce7f721c4fb8859138a1294270f3
Publikováno v:
Neurology International, Vol 15, Iss 3, Pp 896-907 (2023)
High-resolution imaging in small animal models of neurologic disease is a technical challenge. In a pilot project, we have explored a non-destructive synchrotron imaging technique for the 3D visualization of intracerebral tissue transplants in a well
Externí odkaz:
https://doaj.org/article/1e1e5e9729194843a191538656259fc2
Autor:
Elisabeth Schültke, Michael Lerch, Timo Kirschstein, Falko Lange, Katrin Porath, Stefan Fiedler, Jeremy Davis, Jason Paino, Elette Engels, Micah Barnes, Mitzi Klein, Christopher Hall, Daniel Häusermann, Guido Hildebrandt
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 4, Pp 1027-1032 (2022)
Microbeam radiotherapy could help to cure malignant tumours which are currently still considered therapy-resistant. With an irradiation target in the thoracic cavity, the heart would be one of the most important organs at risk. To assess the acute ad
Externí odkaz:
https://doaj.org/article/7c4f0d17d2424fabbc38e89c641ee115
Autor:
Thomas Breslin, Jason Paino, Marie Wegner, Elette Engels, Stefan Fiedler, Helen Forrester, Hannes Rennau, John Bustillo, Matthew Cameron, Daniel Häusermann, Christopher Hall, Dieter Krause, Guido Hildebrandt, Michael Lerch, Elisabeth Schültke
Publikováno v:
Biomimetics, Vol 8, Iss 2, p 230 (2023)
The production of anthropomorphic phantoms generated from tissue-equivalent materials is challenging but offers an excellent copy of the typical environment encountered in typical patients. High-quality dosimetry measurements and the correlation of t
Externí odkaz:
https://doaj.org/article/5010b267b3f845509d3b0414cf2f17ab
Autor:
Bernd Frerker, Stefan Fiedler, Timo Kirschstein, Falko Lange, Katrin Porath, Tina Sellmann, Leonie Kutzner, Fabian Wilde, Julian Moosmann, Rüdiger Köhling, Guido Hildebrandt, Elisabeth Schültke
Publikováno v:
Cells, Vol 12, Iss 1, p 176 (2022)
Background: High-dose-rate radiotherapy has shown promising results with respect to normal tissue preservation. We developed an ex vivo model to study the physiological effects of experimental radiotherapy in the rodent esophageal smooth muscle. Meth
Externí odkaz:
https://doaj.org/article/8710f0122d5c499786b0045983c125aa
Autor:
Munir A. Al-Zeer, Franziska Prehn, Stefan Fiedler, Ulrich Lienert, Michael Krisch, Johanna Berg, Jens Kurreck, Guido Hildebrandt, Elisabeth Schültke
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9951 (2022)
Radiotherapy is an important component in the treatment of lung cancer, one of the most common cancers worldwide, frequently resulting in death within only a few years of diagnosis. In order to evaluate new therapeutic approaches and compare their ef
Externí odkaz:
https://doaj.org/article/307514936677490a8e71ee222dc50e06
Autor:
Felix Jaekel, Elke Bräuer-Krisch, Stefan Bartzsch, Jean Laissue, Hans Blattmann, Marten Scholz, Julia Soloviova, Guido Hildebrandt, Elisabeth Schültke
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8319 (2022)
Microbeam radiotherapy (MRT), an experimental high-dose rate concept with spatial fractionation at the micrometre range, has shown a high therapeutic potential as well as good preservation of normal tissue function in pre-clinical studies. We investi
Externí odkaz:
https://doaj.org/article/4129c2daec4442a4b89b96de8ef82964
Autor:
Gohar Tsakanova, Ani Stepanyan, Elina Arakelova, Violetta Ayvazyan, Vahan Tonoyan, Arsen Arakelyan, Guido Hildebrandt, Elisabeth Schültke
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253553 (2021)
For the last years, copper complexes have been intensively implicated in biomedical research as components of cancer treatment. Herewith, we provide highlights of the synthesis, physical measurements, structural characterization of the newly develope
Externí odkaz:
https://doaj.org/article/f1353d88a70b41c39a10fdd33caca883
Autor:
Falko Lange, Jens Hartung, Clara Liebelt, Julius Boisserée, Tobias Resch, Katrin Porath, Max Frederik Hörnschemeyer, Gesine Reichart, Tina Sellmann, Valentin Neubert, Stephan Kriesen, Guido Hildebrandt, Elisabeth Schültke, Rüdiger Köhling, Timo Kirschstein
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
An abnormal glutamate signaling of glioblastoma may contribute to both tumor progression and the generation of glioma-associated epileptic seizures. We hypothesized that the AMPA receptor antagonist perampanel (PER) could attenuate tumor growth and e
Externí odkaz:
https://doaj.org/article/766c75cc8c414ac6959b68edd833ce6e
Autor:
Falko Lange, Timo Kirschstein, Jeremy Davis, Jason Paino, Micah Barnes, Mitzi Klein, Katrin Porath, Paula Stöhlmacher, Stefan Fiedler, Marcus Frank, Rüdiger Köhling, Guido Hildebrandt, Daniel Hausermann, Michael Lerch, Elisabeth Schültke
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 114:143-152
Microbeam radiation therapy (MRT) has shown several advantages compared with conventional broad-beam radiation therapy in small animal models, including a better preservation of normal tissue function and improved drug delivery based on a rapidly inc