Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elisabeth, Pfeiffenberger"'
Autor:
Marc Dohmen, Sarah Krieg, Georgios Agalaridis, Xiaoqing Zhu, Saifeldin N. Shehata, Elisabeth Pfeiffenberger, Jan Amelang, Mareike Bütepage, Elena Buerova, Carolina M. Pfaff, Dipanjan Chanda, Stephan Geley, Christian Preisinger, Kei Sakamoto, Bernhard Lüscher, Dietbert Neumann, Jörg Vervoorts
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
AMPK integrates information about a cell’s energy status to inform decisions about cellular processes, including autophagy. Here the authors identify cyclin Y as an AMPK substrate, which phosphorylates cyclin Y and promotes its interaction with CDK
Externí odkaz:
https://doaj.org/article/c3a2cb60cb8f4b428a1b0a25d64f8433
Autor:
Elisabeth Pfeiffenberger, Chandrahas Koumar Ratnacaram, Ernesto Guccione, Joel Heng Loong Tan, Radoslaw M. Sobota, Xavier Bisteau, Daniel M. Messerschmidt, Heike Wollmann, Philipp Kaldis, Jayantha Gunaratne, Sheena Wee, Joanna H.S. Lee, Diana Low, Nathan Palmer, S. Zakiah A. Talib
Publikováno v:
The Journal of cell biology, 218 (9
The Journal of Cell Biology
The Journal of Cell Biology
Palmer et al. identify NRF1 as a novel CDK2 interactor and substrate. This interaction was found to be important for the DNA-binding activity of NRF1. Their findings demonstrate that the loss of CDK2 expression impairs the regulation of NRF1 transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773736be05302fa890f7f57139b06865
https://doi.org/10.1083/jcb.201903125
https://doi.org/10.1083/jcb.201903125
Autor:
Elena Buerova, Kei Sakamoto, Christian Preisinger, Bernhard Lüscher, Jörg Vervoorts, Mareike Bütepage, Sarah Krieg, Stephan Geley, Dipanjan Chanda, Carolina M. Pfaff, Marc Dohmen, Georgios Agalaridis, Saifeldin N. Shehata, Xiaoqing Zhu, Jan Amelang, Elisabeth Pfeiffenberger, Dietbert Neumann
Publikováno v:
Nature Communications, 11(1):1032. Nature Publishing Group
Dohmen, M, Krieg, S, Agalaridis, G, Zhu, X, Shehata, S N, Pfeiffenberger, E, Amelang, J, Bütepage, M, Buerova, E, Pfaff, C M, Chanda, D, Geley, S, Preisinger, C, Sakamoto, K, Lüscher, B, Neumann, D & Vervoorts, J 2020, ' AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy ', Nature Communications, vol. 11, no. 1, 1032 . https://doi.org/10.1038/s41467-020-14812-0
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Dohmen, M, Krieg, S, Agalaridis, G, Zhu, X, Shehata, S N, Pfeiffenberger, E, Amelang, J, Bütepage, M, Buerova, E, Pfaff, C M, Chanda, D, Geley, S, Preisinger, C, Sakamoto, K, Lüscher, B, Neumann, D & Vervoorts, J 2020, ' AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy ', Nature Communications, vol. 11, no. 1, 1032 . https://doi.org/10.1038/s41467-020-14812-0
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The AMP-activated protein kinase (AMPK) is a master sensor of the cellular energy status that is crucial for the adaptive response to limited energy availability. AMPK is implicated in the regulation of many cellular processes, including autophagy. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a596c455e15e84047461fa9d0ca10bb8
https://lirias.kuleuven.be/handle/20.500.12942/716305
https://lirias.kuleuven.be/handle/20.500.12942/716305
Autor:
Kia Ngee Low, Igor V. Kurochkin, Christine M. F. Goh, Matias J. Caldez, Vincenzo Coppola, Philipp Kaldis, Frank Eisenhaber, Yoganathan Kanagasundaram, Sebastian Maurer-Stroh, Hyungwon Choi, Lakshmi Gopinathan, Elisabeth Pfeiffenberger, Yang Lay Kien, Oliver S. Jones, Joanna Niska-Blakie, Chee Bing Ong, Lino Tessarollo
Publikováno v:
Cellular and Molecular Life Sciences
SUGCT (C7orf10) is a mitochondrial enzyme that synthesizes glutaryl-CoA from glutarate in tryptophan and lysine catabolism, but it has not been studied in vivo. Although mutations in Sugct lead to Glutaric Aciduria Type 3 disease in humans, patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c640f485606b4af88226aea87333d8c
https://pubmed.ncbi.nlm.nih.gov/31722069
https://pubmed.ncbi.nlm.nih.gov/31722069
Autor:
Keiko Nakayama, Shuhei Kotoshiba, Anisa Rahim, Elisabeth Pfeiffenberger, Keiichi I. Nakayama, Philipp Kaldis, Lakshmi Gopinathan, Leah A. Vardy
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843(2):436-445
Cyclin-dependent kinase 2 (Cdk2) is dispensable for mitotic cell cycle progression and Cdk2 knockout mice are viable due to the compensatory functions of other Cdks. In order to assess the role of Cdk2 under limiting conditions, we used Skp2 knockout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eb1939b09e295df092fd365541b1a7
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1448
RNA interference (RNAi) has become an essential technology for functional gene analysis. Its success depends on the effective expression of target gene-specific RNAi-inducing small double-stranded interfering RNA molecules (siRNAs). Here, were descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7c5d6f94255d0a091f697178ebbfd6b
https://pubmed.ncbi.nlm.nih.gov/27317178
https://pubmed.ncbi.nlm.nih.gov/27317178
Publikováno v:
Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools ISBN: 9781493937516
RNA interference (RNAi) has become an essential technology for functional gene analysis. Its success depends on the effective expression of target gene-specific RNAi-inducing small double-stranded interfering RNA molecules (siRNAs). Here, were descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ffda3380a3d3ad6847778e920b01685
https://doi.org/10.1007/978-1-4939-3753-0_10
https://doi.org/10.1007/978-1-4939-3753-0_10