Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elisabeth, Minthorn"'
Autor:
Rakesh Kumar, Jeffrey M. Axten, Beat M. Jucker, Hasan Alsaid, Anthony E. Choudhry, Nathan Gaul, Aaron Goetz, Brent Sanders, Thomas B. Stanley, Katherine Moss, David J. Figueroa, Shu-Yun Zhang, Elisabeth Minthorn, Qi Liu, Charity Atkins
Supplementary Material PDF file - 147K, Supplementary Methods: Immunohistochemistry and magnetic resonance imaging. Supplementary Table 1: Kinase selectivity profiling of GSK2656157. Supplementary Table 2: Gene list for Human UPR array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bae45c3c74dc63b99fc43eade9948d3
https://doi.org/10.1158/0008-5472.22399736
https://doi.org/10.1158/0008-5472.22399736
Autor:
Rakesh Kumar, Jeffrey M. Axten, Beat M. Jucker, Hasan Alsaid, Anthony E. Choudhry, Nathan Gaul, Aaron Goetz, Brent Sanders, Thomas B. Stanley, Katherine Moss, David J. Figueroa, Shu-Yun Zhang, Elisabeth Minthorn, Qi Liu, Charity Atkins
Supplementary Figures 1-3 PDF file - 245K, Supplementary Figure 1: Dose-dependent pharmacodynamic effect of GSK2656157 on PERK in mouse pancreas. Supplementary Figure 2: Specificity of phospho-PERK antibody in mouse cells. Supplementary Figure 3: Eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be769ac9df05c7852876b0e255be076
https://doi.org/10.1158/0008-5472.22399739
https://doi.org/10.1158/0008-5472.22399739
Autor:
Jesús R, Medina, Xinrong, Tian, William H, Li, Dominic, Suarez, James F, Mack, Louis, LaFrance, Cuthbert, Martyr, James, Brackley, Christina, Di Marco, Ralph, Rivero, Dirk A, Heerding, Charles, McHugh, Elisabeth, Minthorn, Aishwarya, Bhaskar, Jacob, Rubin, Michael, Butticello, Christopher, Carpenter, Eldridge N, Nartey, Thomas J, Berrodin, Lorena A, Kallal, Biju, Mangatt
Publikováno v:
Journal of medicinal chemistry. 64(21)
Elevated expression of the
Autor:
Cathrine L, Denton, Elisabeth, Minthorn, Stanley W, Carson, Graeme C, Young, Lauren E, Richards-Peterson, Jeffrey, Botbyl, Chao, Han, Royce A, Morrison, Samuel C, Blackman, Daniele, Ouellet
Publikováno v:
Journal of clinical pharmacology. 53(9)
Dabrafenib is an orally bioavailable, potent, and selective inhibitor of human wild-type BRAF and CRAF kinases as well as mutant forms of BRAF kinase. The aim of this phase 1, single-center, open-label study in four patients with BRAF mutation-positi