Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elisabete Carapuça"'
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract This was a Phase I, randomized, double‐blinded, three‐arm, single‐dose, parallel study aimed to demonstrate pharmacokinetic (PK) similarity between MB09 (a denosumab biosimilar candidate) and reference denosumab (XGEVA® from European
Externí odkaz:
https://doaj.org/article/57c1e8cb07884d4692bbf9f7180b3eae
Autor:
Elisabete Carapuça, Y. K. Stella Man, Julie Foster, Gunnel Halldén, Alan L. Parker, James A. Davies, Jane K. Sosabowski
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Early phase clinical trials have demonstrated good therapeutic index for oncolytic adenoviruses in patients with solid tumours when administered intratumorally, resulting in local tumour elimination. Entrapment and binding of adenovirus to erythrocyt
Publikováno v:
Porto Biomedical Journal
Ovarian cancer is the 5th most common cancer in UK women with a high relapse rate. The overall survival for ovarian cancer has remained low for decades prompting a real need for new therapies. Recurrent ovarian cancer remains confined in the peritone
Autor:
Michael D. Williams, Prabhu Arumugam, Emilios Gemenetzidis, Richard Grose, Hemant M. Kocher, Frances M. Richards, Abigail S Wilson, Francesca R. Delvecchio, Elisabete Carapuça, Nicholas R. Lemoine, Christine Feig, Tashinga E. Bapiro
Publikováno v:
Pancreatology. 16:S4
Publikováno v:
Cancer Research. 75:B72-B72
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an intense desmoplastic stroma, due to the activation of pancreatic stellate cells (PSC). The activated PSC are characterized by a reduction of fat droplets, expression of α-smo
Autor:
Adriano R. Azzoni, Elisabete Carapuça, Filipe Mergulhão, Gabriel A. Monteiro, D. Miguel F. Prazeres
Publikováno v:
Microbial Cell Factories, Vol 5, Iss Suppl 1, p P50 (2006)
Background Determination of the plasmid content in prokaryotic cells during plasmid DNA (pDNA) production and in eukaryotic cells after transfection is crucial for DNA vaccine development. In Escherichia coli, pDNA is usually determined after plasmid
Time-course determination of plasmid content in eukaryotic and prokaryotic cells using real-time PCR
Autor:
Elisabete Carapuça, Duarte M. F. Prazeres, Gabriel A. Monteiro, Filipe Mergulhão, Adriano R. Azzoni
Publikováno v:
Molecular biotechnology. 37(2)
A Real-Time PCR method was developed to monitor the plasmid copy number (PCN) in Escherichia coli and Chinese hamster ovary (CHO) cells. E. coli was transformed with plasmids containing a ColE1 or p15A origin of replication and CHO cells were transfe
Publikováno v:
Gastroenterology. 146:S-498
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an intense desmoplastic stroma, due to the activation of pancreatic stellate cells (PSC). The activated PSC are characterized by a reduction of fat droplets, expression of α-smo