Effectiveness and safety of vedolizumab in inflammatory bowel disease patients aged 60 and over: an observational multicenter UK experience

Autor: Peter M. Irving, Hajir Ibraheim, Jonathan Digby-Bell, A Ibarra, Ailsa Hart, Nick Powell, Ashish Srinivasan, Philip Oppong, Elisabeta Compot, Klaartje Kok, Irena Norman, Julia Biedermann, Gareth Parkes, Oliver Brain, Miles Parkes, Mark A Samaan, Issrah Jawad, Bu'Hussain Hayee, Jonathan Segal, Joanna Rimmer

Publikováno v: Annals of Gastroenterology

Background The GEMINI trials established the efficacy of vedolizumab in moderate-to-severe inflammatory bowel disease (IBD) and demonstrated a favorable safety profile, suggesting it may be advantageous in older patients at greater risk of treatment-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fe8c3891b031ea9b6d9579f396146c
https://pubmed.ncbi.nlm.nih.gov/32127738

Effectiveness and safety of vedolizumab in inflammatory bowel disease patients aged 60 and over: an observational multicenter UK experience.

Autor: Ibraheim H; IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell).; Centre for Inflammation Biology and Cancer Immunology (CIBCI), King's College London (Hajir Ibraheim, Nick Powell)., Samaan MA; IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell)., Srinivasan A; Translational Gastroenterology Unit, Oxford University Hospitals Trust, Oxford (Ashish Srinivasan, Oliver Brain)., Brain O; Translational Gastroenterology Unit, Oxford University Hospitals Trust, Oxford (Ashish Srinivasan, Oliver Brain)., Digby-Bell J; IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell)., Irving PM; IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell)., Norman I; IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell)., Jawad I; Department of Gastroenterology, University College London Hospital, London (Issrah Jawad)., Biedermann J; Department of Gastroenterology, King's College Hospital, Denmark Hill, London (Julia Biedermann, Bu'Hussain Hayee)., Ibarra A; Department of Gastroenterology, Barts Health NHS Trust, London (Ana Ibarra, Klaartje Bel Kok, Gareth Parkes)., Kok KB; Department of Gastroenterology, Barts Health NHS Trust, London (Ana Ibarra, Klaartje Bel Kok, Gareth Parkes)., Parkes G; Department of Gastroenterology, Barts Health NHS Trust, London (Ana Ibarra, Klaartje Bel Kok, Gareth Parkes)., Rimmer J; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge (Joanna Rimmer, Elisabeta Compot, Miles Parkes)., Compot E; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge (Joanna Rimmer, Elisabeta Compot, Miles Parkes)., Parkes M; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge (Joanna Rimmer, Elisabeta Compot, Miles Parkes)., Segal J; St. Mark's Hospital, IBD Unit, Harrow, London (Jonathan Segal, Philip Oppong, Ailsa Hart).; Division of Integrative Systems Medicine and Digestive disease, Department of Surgery and Cancer, Faculty of medicine, Imperial College London, London (Jonathan Segal, Ailsa Hart), UK., Oppong P; St. Mark's Hospital, IBD Unit, Harrow, London (Jonathan Segal, Philip Oppong, Ailsa Hart)., Hart A; St. Mark's Hospital, IBD Unit, Harrow, London (Jonathan Segal, Philip Oppong, Ailsa Hart).; Division of Integrative Systems Medicine and Digestive disease, Department of Surgery and Cancer, Faculty of medicine, Imperial College London, London (Jonathan Segal, Ailsa Hart), UK., Hayee B; Department of Gastroenterology, King's College Hospital, Denmark Hill, London (Julia Biedermann, Bu'Hussain Hayee)., Powell N; IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell).; Centre for Inflammation Biology and Cancer Immunology (CIBCI), King's College London (Hajir Ibraheim, Nick Powell).

Publikováno v: Annals of gastroenterology [Ann Gastroenterol] 2020 Mar-Apr; Vol. 33 (2), pp. 170-177. Date of Electronic Publication: 2020 Jan 07.