Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Elisabet Selga"'
Autor:
Rebecca Martínez-Moreno, Alexandra Pérez-Serra, Elisabet Selga, David Carreras, Begoña Aran, Bernd Kuebler, Fabiana S. Scornik, Guillermo J. Pérez, Ramon Brugada
Publikováno v:
Stem Cell Research, Vol 73, Iss , Pp 103239- (2023)
Tissue-specific cells differentiated from patient-derived human induced pluripotent stem cells (hiPSC) are a relevant cellular model to study several diseases. We obtained a hiPSC line from skin fibroblasts of a patient affected by familial atrial fi
Externí odkaz:
https://doaj.org/article/a5a6383660434068bac6b7654e908c00
Autor:
Rebecca Martínez-Moreno, David Carreras, Begoña Aran, Bernd Kuebler, Georgia Sarquella-Brugada, Ramon Brugada, Guillermo J. Pérez, Fabiana S. Scornik, Elisabet Selga
Publikováno v:
Stem Cell Research, Vol 63, Iss , Pp 102847- (2022)
Patient-derived induced pluripotent stem cells (iPSC) are a valuable approach to model cardiovascular diseases. We nucleofected non-integrating episomal vectors in skin fibroblasts of three family members carrying a single nucleotide variant (SNV) in
Externí odkaz:
https://doaj.org/article/f7e87c024cea456eb75562679b476f75
Autor:
Rebecca Martínez-Moreno, Alexandra Pérez-Serra, David Carreras, Begoña Aran, Bernd Kuebler, Ramon Brugada, Fabiana S. Scornik, Guillermo J. Pérez, Elisabet Selga
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102717- (2022)
The effects of genetic mutations on protein function can be studied in a physiologically relevant environment using tissue-specific cells differentiated from patient-derived induced pluripotent stem cells (iPSC). However, it is crucial to use iPSC de
Externí odkaz:
https://doaj.org/article/4ca3ce8cdcb64fbba60693a9192209ef
Autor:
Rebecca Martinez-Moreno, Elisabet Selga, Helena Riuró, David Carreras, Mered Parnes, Chandra Srinivasan, Michael F. Wangler, Guillermo J. Pérez, Fabiana S. Scornik, Ramon Brugada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Voltage-gated sodium (NaV) channels are transmembrane proteins that initiate and propagate neuronal and cardiac action potentials. NaV channel β subunits have been widely studied due to their modulatory role. Mice null for Scn1b, which encodes NaV
Externí odkaz:
https://doaj.org/article/2ad4cd477ccb42d1a7a8a681f0aa219b
Autor:
Irene Mademont-Soler, Mel Lina Pinsach-Abuin, Helena Riuró, Jesus Mates, Alexandra Pérez-Serra, Mònica Coll, José Manuel Porres, Bernat Del Olmo, Anna Iglesias, Elisabet Selga, Ferran Picó, Sara Pagans, Carles Ferrer-Costa, Geòrgia Sarquella-Brugada, Elena Arbelo, Sergi Cesar, Josep Brugada, Óscar Campuzano, Ramon Brugada
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163514 (2016)
Brugada syndrome (BrS) is a form of cardiac arrhythmia which may lead to sudden cardiac death. The recommended genetic testing (direct sequencing of SCN5A) uncovers disease-causing SNVs and/or indels in ~20% of cases. Limited information exists about
Externí odkaz:
https://doaj.org/article/820185f90cb84d599db4cfbb29f8c698
Autor:
Elisabet Selga, Oscar Campuzano, Mel Lina Pinsach-Abuin, Alexandra Pérez-Serra, Irene Mademont-Soler, Helena Riuró, Ferran Picó, Mònica Coll, Anna Iglesias, Sara Pagans, Georgia Sarquella-Brugada, Paola Berne, Begoña Benito, Josep Brugada, José M Porres, Matilde López Zea, Víctor Castro-Urda, Ignacio Fernández-Lozano, Ramon Brugada
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132888 (2015)
Brugada syndrome (BrS) is a rare genetic cardiac arrhythmia that can lead to sudden cardiac death in patients with a structurally normal heart. Genetic variations in SCN5A can be identified in approximately 20-25% of BrS cases. The aim of our work wa
Externí odkaz:
https://doaj.org/article/56d014539506423fac918d59e1ae5a25
Publikováno v:
Bio-Protocol, Vol 3, Iss 16 (2013)
A great way to specifically isolate and quantify proteins in the cell surface membrane is to take advantage of the biotinylation technique. It consists of labeling cell surface proteins with a biotin reagent before lysing the cells, and isolating the
Externí odkaz:
https://doaj.org/article/1ba803732e4e4a85916dc7c6993624c1
Publikováno v:
Bio-Protocol, Vol 3, Iss 16 (2013)
This protocol is used to measure sodium currents from heterologously transfected cells lines, such as HEK293 cells. Standard whole cell patch clamp technique is used to assess ion channel function. This protocol has been used to study cardiac type Na
Externí odkaz:
https://doaj.org/article/b4132e93d7984e5fb65230586d86fbc0
Autor:
Anna Tarradas, Elisabet Selga, Pedro Beltran-Alvarez, Alexandra Pérez-Serra, Helena Riuró, Ferran Picó, Anna Iglesias, Oscar Campuzano, Víctor Castro-Urda, Ignacio Fernández-Lozano, Guillermo J Pérez, Fabiana S Scornik, Ramon Brugada
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53220 (2013)
Brugada syndrome (BrS) is a life-threatening, inherited arrhythmogenic syndrome associated with autosomal dominant mutations in SCN5A, the gene encoding the cardiac Na(+) channel alpha subunit (Na(v)1.5). The aim of this work was to characterize the
Externí odkaz:
https://doaj.org/article/f35596f2e5fc4cb8a5efbfd0cbb568cf
Autor:
Alexandra Pérez-Serra, Guillermo J. Pérez, Elisabet Selga, Fabiana S. Scornik, Ramon Brugada, Alba Moreno-Asso, Mayurika Desai, Seth Anderson, Kristen Thomas
Publikováno v:
Channels, 2013, vol. 7, núm. 4, p. 322-328
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
instname
ResearcherID
Channels
Europe PubMed Central
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
instname
ResearcherID
Channels
Europe PubMed Central
Large conductance calcium-activated potassium (BK) channels are widely expressed in the nervous system. We have recently shown that principal neurons from canine intracardiac ganglia (ICG) express a paxilline- and TEA-sensitive BK current, which incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7474d20538f5dff981779c2cf393f19f
https://hdl.handle.net/2072/372151
https://hdl.handle.net/2072/372151
