Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elisabet Rosàs-Canyelles"'
Autor:
Elly Sinkala, Elodie Sollier-Christen, Corinne Renier, Elisabet Rosàs-Canyelles, James Che, Kyra Heirich, Todd A. Duncombe, Julea Vlassakis, Kevin A. Yamauchi, Haiyan Huang, Stefanie S. Jeffrey, Amy E. Herr
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Circulating tumour cells (CTCs) are rare cells found in the blood of certain cancer patients. Here, the authors develop a cytometry tool that appends a microfluidic western blot to a CTC isolation workflow and apply it to profile a panel of proteins
Externí odkaz:
https://doaj.org/article/07fbb330fecc4ed28810eb8735b09dd0
Autor:
Andrew J. Modzelewski, Lin He, Ana E. Gomez Martinez, Amy E. Herr, Anjali Gopal, Elisabet Rosàs-Canyelles, Alisha Geldert
Publikováno v:
Lab Chip
Lab on a chip, vol 21, iss 12
Lab on a chip, vol 21, iss 12
Protein isoforms play a key role in disease progression and arise from mechanisms involving multiple molecular subtypes, including DNA, mRNA and protein. Recently introduced multimodal assays successfully link genomes and transcriptomes to protein ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399c99f454c653ce9ebf8a474ace7b65
https://doi.org/10.1039/d1lc00073j
https://doi.org/10.1039/d1lc00073j
Publikováno v:
The Analyst, vol 144, iss 3
While profiling of cell surface receptors grants valuable insight on cell phenotype, surface receptors alone cannot fully describe activated downstream signaling pathways, detect internalized receptor activity, or indicate constitutively active signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49901c35de04ccc132fcef271ce55ff5
https://doi.org/10.1039/c8an01441h
https://doi.org/10.1039/c8an01441h
Publikováno v:
Nat Protoc
Although mammalian embryo development depends on critical protein isoforms that arise from embryo-specific nucleic acid modifications, the role of these isoforms is not yet clear. Challenges arise in measuring protein isoforms and nucleic acids from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378f02fe61491b1379df8306cced9ef0
https://pubmed.ncbi.nlm.nih.gov/33452502
https://pubmed.ncbi.nlm.nih.gov/33452502
Publikováno v:
Science Advances
We report a microfluidic platform that maps target protein and mRNA expression with inter- and intraembryonic resolution.
The process by which a zygote develops from a single cell into a multicellular organism is poorly understood. Advances are
The process by which a zygote develops from a single cell into a multicellular organism is poorly understood. Advances are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1280c5ee2eac12c8dfcc3155cff3420b
http://europepmc.org/articles/PMC7176412
http://europepmc.org/articles/PMC7176412
Understanding how a zygote develops from a single cell into a multicellular organism has benefitted from single-cell tools, including RNA sequencing (RNA-Seq) and immunofluorescence (IF). However, scrutinizing inter- and intra-embryonic phenotypic va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546bd612b02164f55ef2127c73777624
https://doi.org/10.1101/357731
https://doi.org/10.1101/357731
Publikováno v:
Lab on a chip. 18(13)
Smooth muscle cell (SMC) heterogeneity plays an important role in vascular remodeling, a life-threatening hallmark of many vascular diseases. However, the characterization of SMCs at the single-cell level is stymied by drawbacks of contemporary singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2700de8c81d2fb09a962e0dcb5d44efb
https://pubmed.ncbi.nlm.nih.gov/29796562
https://pubmed.ncbi.nlm.nih.gov/29796562
Autor:
Kyra Heirich, Elodie Sollier-Christen, Todd A. Duncombe, Kevin A. Yamauchi, Julea Vlassakis, Stefanie S. Jeffrey, Amy E. Herr, Haiyan Huang, Elisabet Rosàs-Canyelles, James Che, Elly Sinkala, Corinne Renier
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Circulating tumour cells (CTCs) are rare tumour cells found in the circulatory system of certain cancer patients. The clinical and functional significance of CTCs is still under investigation. Protein profiling of CTCs would complement the recent adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4759c7ddd29400cfc453df16489d744b
https://doi.org/10.1038/ncomms14622
https://doi.org/10.1038/ncomms14622