Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elisa Suzana Carneiro Pôças"'
Autor:
Afonso Caricati-Neto, François Noël, Humberto Muzi-Filho, Daniele C. Rezende, Luis Eduardo M. Quintas, Valéria M.N. Cunha, Elisa Suzana Carneiro Pôças, Aron Jurkiewicz
Publikováno v:
Journal of Physiology and Biochemistry. 69:207-214
The effect of long-lasting in vivo restriction of nitric oxide (NO) bioavailability on cardiac and renal P-type ATPases critical for intracellular ion homeostasis is controversial. Previous work has shown in eNOS knockout (eNOS �/� ) mice hearts
Autor:
Chaquip D. Neto, François Noël, Paulo R. R. Costa, Fernanda Leitão, Paulo Henrique Cotrim Pimenta, Elisa Suzana Carneiro Pôças, Alcides J. M. da Silva, Natália Araújo Touza
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:8801-8805
The molecular mechanisms involved in Na+,K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan were investigated. We show that this compound decreases the free sulfydryl groups present in the enzyme and that its inhibitory effect is prevented
Autor:
Francisco Radler de Aquino Neto, Luís Nelson Lopes Ferreira Gomes, Henrique Pereira, Marco Aurélio Dal Sasso, Elisa Suzana Carneiro Pôças, Sandra Bahia Ramos, Monica Costa Padilha
Publikováno v:
Journal of the Brazilian Chemical Society. 19:528-531
In the world of performance enhancing drugs, human Chorionic Gonadotrophin (hCG) is increasingly used alone and also in combination with various Anabolic Androgenic Steroid cycles. In males, hCG mimics luteinizing hormone (LH) and helps increase test
Autor:
Alcides J. M. da Silva, François Noël, Elisa Suzana Carneiro Pôças, Natália Araújo Touza, Paulo R. R. Costa
Publikováno v:
Life Sciences. 81:1199-1204
The use of combination drugs is very common in therapeutics as in the treatment of infectious diseases, cancer and heart failure but controversies about analysis of these interactions are frequent. The aim of the present work was to characterize the
Autor:
Paulo R. R. Costa, Elisa Suzana Carneiro Pôças, Chaquip D. Netto, Fernanda Leitão, Camilla D. Buarque, Paulo Henrique Cotrim Pimenta, Alcides J. M. da Silva, Flávia V. Brito, Daniele V.S. Lopes, François Noël
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:7962-7966
Coumestans 2a–i, bearing different patterns of substitution in A- and D-rings, were synthesized and evaluated as inhibitors of kidney Na+,K+-ATPase and ligands for the central benzodiazepine (BZP) receptor. The presence of a hydroxyl group in posit
Publikováno v:
Biochemical Pharmacology. 66:2169-2176
The aim of the present work was to analyse the interaction between Na(+),K(+)-ATPase and one of our recent synthesized coumestans, namely the original molecule 2-methoxy-3,8,9-trihydroxy coumestan (PCALC36). Rat brain (mainly alpha 2 and alpha 3 Na(+
Autor:
Edson X. Albuquerque, François Noël, V.P. Rodrigues, Daniele V de Souza, Flávia V. Brito, Elisa Suzana Carneiro Pôças, Alcides J. M. da Silva, Paulo R. R. Costa, Noelson M.V Silva, Paulo A. Melo, Camilla D. Buarque
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:283-286
Five coumestans with different patterns of oxygenation in rings A and D were synthesized from resorcinol and aromatic aldehydes, and screened for their antimyotoxic activity. The most potent compound ( 2b , IC 50 =1 μM) was selected for study of its
Autor:
Francisco Radler de Aquino Neto, Joaquim F. M. da Silva, Patricia Castro Moreira Dias, Alberto dos Santos Pereira, Mônica Freiman de Souza Ramos, Elisabete Pereira dos Santos, Elisa Suzana Carneiro Pôças, Jari N. Cardoso
Publikováno v:
Zeitschrift für Naturforschung C. 54:395-400
The underivatized hexane and acetone extracts of two propolis samples (from Brazil’s southwest) were analyzed by HT-HRGC (high temperature high resolution gas chromatogrphy) and HT-HRGC coupled to mass spectrometry (HT-HRGC-MS). Several compounds,
Autor:
Nilberto R.F. Nascimento, Ilana Mara Barbosa de Oliveira, Elisa Suzana Carneiro Pôças, Cláudia F. Santos, Luis Eduardo M. Quintas, Daniel Esdras de Andrade Uchoa, Graciana T. Costa, Bruno A. Cardi, Krishnamurti M. Carvalho, Luciana S. Amaral, François Noël, Manassés C. Fonteles, Edilberto R. Silveira, Paula Priscila Correia Costa, Francisco J. Arnaud-Batista
Publikováno v:
American journal of physiology. Renal physiology. 302(8)
Bufadienolides are structurally related to the clinically relevant cardenolides (e.g., digoxin) and are now considered as endogenous steroid hormones. Binding of ouabain to Na+-K+-ATPase has been associated, in kidney cells, to the activation of the
Autor:
Gabriel Parreiras Estolano da Silveira, Daniele V.S. Lopes, Luis Eduardo M. Quintas, Karla Regina da Silva Gram, Elisa Suzana Carneiro Pôças
Publikováno v:
Pharmaceutica Analytica Acta.
The combination of drugs may be a result of a necessary therapeutic strategy against a single disease or a fortuitous treatment of two or more health disorders. In either case, a consequence of such approach is the increased risk of drug interactions