Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elisa Setten"'
Autor:
Elisa Setten, Alessandra Castagna, Josué Manik Nava-Sedeño, Jonathan Weber, Roberta Carriero, Andreas Reppas, Valery Volk, Jessica Schmitz, Wilfried Gwinner, Haralampos Hatzikirou, Friedrich Feuerhake, Massimo Locati
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Renal fibrosis is a progressive process with complex etiopathology, causing organ failure. Here authors present a mathematical model, based on an in vitro system faithfully contemplating macrophage-fibroblast interaction and the metabolic-immunologic
Externí odkaz:
https://doaj.org/article/9bf0aac27ae14ea890d07134746ab045
ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity
Autor:
Matteo Massara, Ornella Bonavita, Benedetta Savino, Nicoletta Caronni, Valeria Mollica Poeta, Marina Sironi, Elisa Setten, Camilla Recordati, Laura Crisafulli, Francesca Ficara, Alberto Mantovani, Massimo Locati, Raffaella Bonecchi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The atypical chemokine receptor ACKR2 regulates immune responses. Here the authors confirm that ACKR2 depletion promotes primary tumor growth but show it has an anti-metastatic effect in mouse models of breast cancer by affecting myeloid differentiat
Externí odkaz:
https://doaj.org/article/3c65e1c5ccf540638c6d891c8d6bd90e
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/25f3500a8ca246c38872036937c59d71
Autor:
Elisa Setten, Alessandra Castagna, Josué Manik Nava-Sedeño, Jonathan Weber, Roberta Carriero, Andreas Reppas, Valery Volk, Jessica Schmitz, Wilfried Gwinner, Haralampos Hatzikirou, Friedrich Feuerhake, Massimo Locati
Publikováno v:
Nature communications. 13(1)
Fibrosis is a progressive biological condition, leading to organ dysfunction in various clinical settings. Although fibroblasts and macrophages are known as key cellular players for fibrosis development, a comprehensive functional model that consider
Autor:
Massimo Locati, Diego Fornasari, Annalisa Maroli, Elisa Setten, Simona Di Lascio, Lorenzo Drufuca, Silvia Cardani, Roberta Benfante
Publikováno v:
Journal of Neuroimmunology. 332:155-166
The α7 nicotinic acetylcholine receptor (CHRNA7) modulates the inflammatory response by activating the cholinergic anti-inflammatory pathway. CHRFAM7A, the human-restricted duplicated form of CHRNA7, has a negative effect on the functioning of α7 r
ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity
Autor:
Massimo Locati, Raffaella Bonecchi, Ornella Bonavita, Camilla Recordati, Matteo Massara, Elisa Setten, Laura Crisafulli, Francesca Ficara, Nicoletta Caronni, Benedetta Savino, Marina Sironi, Valeria Mollica Poeta, Alberto Mantovani
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Atypical chemokine receptors (ACKRs) are regulators of leukocyte traffic, inflammation, and immunity. ACKR2 is a scavenger for most inflammatory CC chemokines and is a negative regulator of inflammation. Here we report that ACKR2 is expressed in hema
Publikováno v:
Frontiers in Immunology
The lymphatic system plays an important role in the induction of the immune response by transporting antigens, inflammatory mediators, and leukocytes from peripheral tissues to draining lymph nodes (LNs). It is emerging that lymphatic endothelial cel