Synergistic impact of innate immunity hyper-activation and endothelial dysfunction on the magnitude of organ failure in the infection-sepsis continuum

Autor: Amanda de la Fuente, Jaime López-Sánchez, Luis Mario Vaquero-Roncero, María Merino García, María Elisa Sánchez Barrado, Miguel Vicente Sánchez-Hernández, Nadia Garcia-Mateo, Jesús Rico-Feijoo, Luis Muñoz-Bellvís, Rafael González de Castro, Ana P. Tedim, Alicia Ortega, Omar Abdel-lah Fernández, Alejandro Suárez-de-la-Rica, Emilio Maseda, Ignacio Trejo González, Geovanna Liszeth García Carrera, José Miguel Marcos-Vidal, Juan Manuel Nieto Arranz, Luis Chiscano-Camón, Ricard Ferrer, Juan Carlos Ruiz-Rodríguez, Juan José González-López, José Alberto Vila Fernández, Regina Prieto Carballo, Raul Lopez-Izquierdo, Sonsoles Garrosa, Beatriz Barón, Carmen Esteban-Velasco, César Aldecoa, Jesús F. Bermejo-Martin

Publikováno v: International Journal of Infectious Diseases, Vol 146, Iss , Pp 107142- (2024)

Objectives: Identifying host response biomarkers implicated in the emergence of organ failure during infection is key to improving the early detection of this complication. Methods: Twenty biomarkers of innate immunity, T-cell response, endothelial d

Externí odkaz: https://doaj.org/article/d193e3546e644fe7a3b40e3197e19adb

Réplica a la carta al director: «Un comentario sobre proteína C reactiva y escala SOFA: una simple escala como factor predictivo temprano de la necesidad de cuidados críticos en los pacientes con neumonía causada por COVID-19 en España»

Autor: Luis Mario Vaquero Roncero, Elisa Sánchez Barrado, Miguel Vicente Sánchez Hernández

Publikováno v: Revista Española de Anestesiología y Reanimación. 69:442-443

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c83235516fd953cf82cb5512385938b2
https://doi.org/10.1016/j.redar.2022.01.001

Date of Admission during COVID-19 Pandemic Impacted Patient Outcomes in Addition to the Higher Efficacy of Tocilizumab Plus High-Dose Corticosteroid Therapy Compared to Tocilizumab Alone

Autor: Moncef Belhassen-García, Antonio Sánchez-Puente, Pedro-Ignacio Dorado-Díaz, Amparo López-Bernús, Jesús Sampedro-Gómez, Raúl Azibeiro-Melchor, Edgard Marcano-Millán, Beatriz Rodríguez-Alonso, María-Elisa Sánchez-Barrado, Ignacio Hernández-García, Ignacio Madruga, Guillermo Hernández-Pérez, Cristina Carbonell, Judit García-Aparicio, Laura Burgos, Eugenia López-Sánchez, Carlos Reina, Ana-María Ramón, Laura Cestero-Ramírez, Fátima Boumhir, Daniel Encinas-Sánchez, María Sánchez-Ledesma, Jacinto Herráez, Patricia Araoz, María-José Sánchez-Crespo, Sandra Rodríguez-Rodríguez, Ana-Elisa Rodríguez-Gude, Miguel-Vicente Sánchez-Hernández, Rafael Borrás, Víctor Sagredo-Meneses, Pedro-Luis Sánchez, Miguel Marcos, José-Ángel Martín-Oterino

Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 11, Iss 198, p 198 (2022)
Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 198

Background: The evidence for the efficacy of glucocorticoids combined with tocilizumab (TCZ) in COVID-19 comes from observational studies or subgroup analysis. Our aim was to compare outcomes between hospitalized COVID-19 patients who received high-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a71977e8089a802b60bac0f38696af1
https://pubmed.ncbi.nlm.nih.gov/35011938

C-Reactive protein and SOFA score as early predictors of critical care requirement in patients with COVID-19 pneumonia in Spain

Autor: Luis Mario Vaquero-Roncero, Elisa Sánchez-Barrado, Daniel Escobar-Macias, Pilar Arribas-Pérez, Jose Ramón Gonzalez-Porras, Jesús F Bermejo-Martín, Cristina Doncel, JM Bastida, Azucena Hernández-Valero, Carolina Jambrina-García Montoto, José Sánchez-Crespo, Pablo Alonso-Hernández, Domingo Bustos-García, Antonio Rodríguez-Calvo, Gerardo Riesco-Galache, Raúl Alzibeíro, Alberto Hernández-Sánchez, Rocío Eiros, M Carmen Vargas, María Ángeles Martín, Teresa López, José Alfonso Sastre, José Carlos Garzón, Mar Fernández, Belén García, M Magdalena Muñoz, María Isabel Martínez, Gonzalo García, Agustín Díaz, Edgar Marcano, Víctor Sagredo-Meneses, Miguel Vicente Sánchez-Hernandez

BackgroundSome patients infected by SARS-CoV-2 in the recent pandemic have required critical care, becoming one of the main limitations of the health systems. Our objective has been to identify potential markers at admission predicting the need for c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2ab17febc34c41f251725d8eaaa8f3
https://doi.org/10.1101/2020.05.22.20110429

Clinical guideline for diagnosis and surgical treatment of obstructive sleep apnea syndrome in patients from two to eight years old

Autor: Pablo Santos-Gorjón, Amparo Sánchez-Serrano, María Gil-Melcón, Ana Marín-Cassinello, María Carmen Martín-Gómez, Verísima Barajas-Sánchez, Fernando Benito-González, Elisa Sánchez-Barrado, José Luis Fernández-Sánchez, José Carlos Morán-Sánchez, Teresa Sánchez-Velez, Ana Cristina Morales-Martín, Clara Diego-Pérez, Gemma Vázquez-Casares, José Antonio Blanco-Rueda, Enrique Calvo-Boizas, Arturo De Paz-Sánchez

Publikováno v: GREDOS. Repositorio Institucional de la Universidad de Salamanca
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Introduction and objective: The adenotonsillar hypertrophy is the fundamental cause of childhood obstructive sleep apnea syndrome (OSAS), a frequent pathology that can cause a series of important complications. In certain circumstances, it can be dia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf0935b08c3d1ead9bd75d9db3917bd
http://hdl.handle.net/10366/142031