Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Elisa Roztocil"'
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor originally identified as an environmental sensor of xenobiotic chemicals. However, studies have revealed that the AHR regulates crucial aspects of cell growth and metaboli
Externí odkaz:
https://doaj.org/article/a824b0054a2d4e5c815c4d2fc7c351da
Autor:
Victor Wang, Alison Heffer, Elisa Roztocil, Steven E Feldon, Richard T Libby, Collynn F Woeller, Ajay E Kuriyan
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0271950 (2022)
Proliferative vitreoretinopathy (PVR) is characterized by the growth and contraction of cellular membranes within the vitreous cavity and on both surfaces of the retina, resulting in recurrent retinal detachments and poor visual outcomes. Proinflamma
Externí odkaz:
https://doaj.org/article/e55e75c4d8e04bb282c587e5d97fc43a
Autor:
Alison M Heffer, Jacob Proaño, Elisa Roztocil, Richard P Phipps, Steven E Feldon, Krystel R Huxlin, Patricia J Sime, Richard T Libby, Collynn F Woeller, Ajay E Kuriyan
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222596 (2019)
Proliferative vitreoretinopathy (PVR) is characterized by membranes that form in the vitreous cavity and on both surfaces of the retina, which results in the formation of tractional membranes that can cause retinal detachment and intrinsic fibrosis o
Externí odkaz:
https://doaj.org/article/15194b676123429b95d8985914c380bd
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222779 (2019)
Thyroid eye disease (TED) can lead to scar formation and tissue remodeling in the orbital space. In severe cases, the scarring process leads to sight-threatening pathophysiology. There is no known effective way to prevent scar formation in TED patien
Externí odkaz:
https://doaj.org/article/04978ac48e1c4d8b9aa3be3aa003dcab
Autor:
Steven E. Feldon, Elisa Roztocil, Collynn F. Woeller, Christine L. Hammond, Vardaan Gupta, Mithra O. Gonzalez
Publikováno v:
Surv Ophthalmol
Thyroid eye disease (TED) is an autoimmune disorder that manifests in the orbit. In TED, the connective tissue behind the eye becomes inflamed and remodels with increased fat accumulation and/or increased muscle and scar tissue. As orbital tissue exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f815cc004d8a4e05fc0217af302c323
https://doi.org/10.1016/j.survophthal.2021.08.010
https://doi.org/10.1016/j.survophthal.2021.08.010
Autor:
Elisa Roztocil, Min Yee, J. Edward Puzas, Sydney A. Lim, Collynn F. Woeller, Eric E. Beier, Michael A. O'Reilly
Publikováno v:
Free Radic Biol Med
Preterm birth is a risk factor for growth failure and development of respiratory disease in children and young adults. Their early exposure to oxygen may contribute to lung disease because adult mice exposed to hyperoxia as neonates display reduced l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32b322608907a75242ab6f8de7676b9
https://doi.org/10.1016/j.freeradbiomed.2021.03.005
https://doi.org/10.1016/j.freeradbiomed.2021.03.005
Publikováno v:
Frontiers in toxicology. 4
The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor originally identified as an environmental sensor of xenobiotic chemicals. However, studies have revealed that the AHR regulates crucial aspects of cell growth and metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d00524986c98be99c493ccf78f5f28
https://pubmed.ncbi.nlm.nih.gov/35295218
https://pubmed.ncbi.nlm.nih.gov/35295218
Autor:
Christine L. Hammond, Elisa Roztocil, Collynn F. Woeller, Steven E. Feldon, Mithra O. Gonzalez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Thyroid eye disease (TED) affects 25–50% of patients with Graves’ Disease. In TED, collagen accumulation leads to an expansion of the extracellular matrix (ECM) which causes destructive tissue remodeling. The purpose of this study was to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37c7864a42413f433e73114001fbe70
https://pubmed.ncbi.nlm.nih.gov/32439897
https://pubmed.ncbi.nlm.nih.gov/32439897
Autor:
Steven E. Feldon, Collynn F. Woeller, Elisa Roztocil, Richard P. Phipps, Christine L. Hammond
Publikováno v:
The American Journal of Pathology. 186:3189-3202
Thyroid eye disease (TED) is a degenerative disease that manifests with detrimental tissue remodeling, myofibroblast accumulation, and scarring in the orbit of affected individuals. Currently, there are no effective therapies for TED that target or p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f585174ddf6163517dc9f73d107cd1de
https://doi.org/10.1016/j.ajpath.2016.08.017
https://doi.org/10.1016/j.ajpath.2016.08.017
Autor:
Christine L. Hammond, Steven E. Feldon, Elisa Roztocil, Collynn F. Woeller, Mithra O. Gonzalez
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Thyroid eye disease (TED) is a condition that causes the tissue behind the eye to become inflamed and can result in excessive fatty tissue accumulation in the orbit. Two subpopulations of fibroblasts reside in the orbit: those that highly exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc453998059cf7f5417d043dfd90389f
https://doi.org/10.1167/iovs.62.1.29
https://doi.org/10.1167/iovs.62.1.29