A transcriptome-based signature of pathological angiogenesis predicts breast cancer patient survival.

Autor: Rodrigo Guarischi-Sousa, Jhonatas S Monteiro, Lilian C Alecrim, Jussara S Michaloski, Laura B Cardeal, Elisa N Ferreira, Dirce M Carraro, Diana N Nunes, Emmanuel Dias-Neto, Jüri Reimand, Paul C Boutros, João C Setubal, Ricardo J Giordano

Publikováno v: PLoS Genetics, Vol 15, Iss 12, p e1008482 (2019)

The specific genes and molecules that drive physiological angiogenesis differ from those involved in pathological angiogenesis, suggesting distinct mechanisms for these seemingly related processes. Unveiling genes and pathways preferentially associat

Externí odkaz: https://doaj.org/article/bd9ea154b54a4fc9a8adc64f2394eb23

Complex Landscape of Germline Variants in Brazilian Patients With Hereditary and Early Onset Breast Cancer

Autor: Giovana T. Torrezan, Fernanda G. dos Santos R. de Almeida, Márcia C. P. Figueiredo, Bruna D. de Figueiredo Barros, Cláudia A. A. de Paula, Renan Valieris, Jorge E. S. de Souza, Rodrigo F. Ramalho, Felipe C. C. da Silva, Elisa N. Ferreira, Amanda F. de Nóbrega, Paula S. Felicio, Maria I. Achatz, Sandro J. de Souza, Edenir I. Palmero, Dirce M. Carraro

Publikováno v: Frontiers in Genetics
Frontiers in Genetics, Vol 9 (2018)
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN

Pathogenic variants in known breast cancer (BC) predisposing genes explain only about 30% of Hereditary Breast Cancer (HBC) cases, whereas the underlying genetic factors for most families remain unknown. Here, we used whole-exome sequencing (WES) to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed201fa5325694820ae737c690e93e5
https://pubmed.ncbi.nlm.nih.gov/29868112