Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Elisa M, Vuorinen"'
Autor:
Kirsi J. Rautajoki, Serafiina Jaatinen, Anja Hartewig, Aliisa M. Tiihonen, Matti Annala, Iida Salonen, Masi Valkonen, Vili Simola, Elisa M. Vuorinen, Anni Kivinen, Minna J. Rauhala, Riikka Nurminen, Kendra K. Maass, Sirpa-Liisa Lahtela, Arja Jukkola, Olli Yli-Harja, Pauli Helén, Kristian W. Pajtler, Pekka Ruusuvuori, Joonas Haapasalo, Wei Zhang, Hannu Haapasalo, Matti Nykter
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract As the progression of low-grade diffuse astrocytomas into grade 4 tumors significantly impacts patient prognosis, a better understanding of this process is of paramount importance for improved patient care. In this project, we analyzed match
Externí odkaz:
https://doaj.org/article/93bb5201f4a448cca5fb328e55e9e60a
Autor:
Tuomo J Meretoja, Ruixian Liu, Diether Lambrechts, Johanna Mattson, Satu Mustjoki, Päivi Saavalainen, Bram Boeckx, Maija Hollmen, Rita Turpin, Pauliina M Munne, Aino Peura, Jenna H Rannikko, Gino Philips, Natasha Salmelin, Elina Hurskainen, Ilida Suleymanova, July Aung, Elisa M Vuorinen, Laura Lehtinen, Minna Mutka, Panu E Kovanen, Laura Niinikoski, Andrei Goga, Jeroen Pouwels, Juha Klefström
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Combining cytotoxic chemotherapy or novel anticancer drugs with T-cell modulators holds great promise in treating advanced cancers. However, the response varies depending on the tumor immune microenvironment (TIME). Therefore, there is a c
Externí odkaz:
https://doaj.org/article/cffa2828cea442bea9cecbc2dda3a9f7
Autor:
Kirsi J. Rautajoki, Serafiina Jaatinen, Aliisa M. Tiihonen, Matti Annala, Elisa M. Vuorinen, Anni Kivinen, Minna J. Rauhala, Kendra K. Maass, Kristian W. Pajtler, Olli Yli-Harja, Pauli Helén, Joonas Haapasalo, Hannu Haapasalo, Wei Zhang, Matti Nykter
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Oligodendrogliomas are typically associated with the most favorable prognosis among diffuse gliomas. However, many of the tumors progress, eventually leading to patient death. To characterize the changes associated with oligodendroglioma rec
Externí odkaz:
https://doaj.org/article/217af1ece6ce40dc840de8b5664b04d5
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Nucleocytoplasmic transport is a tightly regulated process carried out by specific transport machinery, the defects of which may lead to a number of diseases including cancer. Karyopherin alpha 7 (KPNA7), the newest member of the
Externí odkaz:
https://doaj.org/article/658d013ab1004fedbbd21306c7f87e56
Autor:
Rita Turpin, Ruixian Liu, Pauliina M. Munne, Aino Peura, Jenna H. Rannikko, Gino Philips, Bram Boeckx, Natasha Salmelin, Elina Hurskainen, Ilida Suleymanova, Elisa M. Vuorinen, Laura Lehtinen, Minna Mutka, Panu E. Kovanen, Laura Niinikoski, Tuomo Meretoja, Johanna Mattson, Satu Mustjoki, Päivi Saavalainen, Andrei Goga, Diether Lambrechts, Jeroen Pouwels, Maija Hollmén, Juha Klefström
Combining cytotoxic chemotherapy or novel anticancer drugs with T-cell modulators holds great promise in treating advanced cancers. However, the response varies depending on the tumor immune microenvironment (TIME). Therefore, there is a clear need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e98c0d5b4e56701de3c89761921281
https://doi.org/10.1101/2023.05.10.539944
https://doi.org/10.1101/2023.05.10.539944
Autor:
Kirsi J. Granberg, Matti Nykter, Juha Kesseli, Paavo Hannus, Elisa M. Vuorinen, Ismaïl Hermelo, Suvi Luoto
The immunosuppressive microenvironment in glioblastoma (GBM) prevents an efficient antitumoral immune response and enables tumor formation and growth. Although an understanding of the nature of immunosuppression is still largely lacking, it is import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5c0958d71a02572c0034823fac0f26b
https://doi.org/10.1158/0008-5472.c.6510554.v1
https://doi.org/10.1158/0008-5472.c.6510554.v1
Autor:
Kirsi J. Granberg, Matti Nykter, Juha Kesseli, Paavo Hannus, Elisa M. Vuorinen, Ismaïl Hermelo, Suvi Luoto
File contains supplementary figures S1-S12. Figures include the concept, results and validation of the regression analysis, estimated cell proportions for all the non-malignant reference cells and tissues, validation of immune subgroups in separate G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7898c2131ea4e2e889761ecc4071e72
https://doi.org/10.1158/0008-5472.22420100
https://doi.org/10.1158/0008-5472.22420100
Table S3 from Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma
Autor:
Kirsi J. Granberg, Matti Nykter, Juha Kesseli, Paavo Hannus, Elisa M. Vuorinen, Ismaïl Hermelo, Suvi Luoto
Tables contain immune system related Gene ontology and KEGG pathway enrichments for identified immune response related gene clusters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c750710ce50273d448f4015f36b772f
https://doi.org/10.1158/0008-5472.22420091
https://doi.org/10.1158/0008-5472.22420091
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the authors notified us that the Additional File 1 contains reviewer comments instead of the Supplementary tables.
Externí odkaz:
https://doaj.org/article/10869042cb954106ba0943c7c4d73413
Autor:
Mari L. Björkman, Elisa M. Vuorinen, Juho Jalkanen, Marie-Louise Fjällskog, Jussi Koivunen, Teppo Huttunen, Maija Hollmén, Petri Bono
Publikováno v:
Cancer Research. 83:4334-4334
Introduction: Clever-1 is an immunosuppressive scavenger receptor expressed on tumor associated macrophages. High levels of Clever-1 are associated with poor survival, T-cell exclusion and dysfunction, and immunotherapy resistance. Bexmarilimab (FP-1