Výsledky vyhledávání - "Elisa Lubian"

Akademický článek

Multifunctional, CD44v6-Targeted ORMOSIL Nanoparticles Enhance Drugs Toxicity in Cancer Cells

Autor: Lucía Morillas-Becerril, Elektra Peta, Luca Gabrielli, Venera Russo, Elisa Lubian, Luca Nodari, Maria Grazia Ferlin, Paolo Scrimin, Giorgio Palù, Luisa Barzon, Ignazio Castagliuolo, Fabrizio Mancin, Marta Trevisan

Publikováno v: Nanomaterials, Vol 10, Iss 2, p 298 (2020)

Drug-loaded, PEGylated, organic-modified silica (ORMOSIL) nanoparticles prepared by microemulsion condensation of vinyltriethoxysilane (VTES) were investigated as potential nanovectors for cancer therapy. To target cancer stem cells, anti-CD44v6 anti

Externí odkaz: https://doaj.org/article/2d602a1f37d64cb4a6e6e50555f3eff0

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Akademický článek

Selective Targeting of Proteins by Hybrid Polyoxometalates: Interaction Between a Bis-Biotinylated Hybrid Conjugate and Avidin

Autor: Valeria A. Zamolo, Gloria Modugno, Elisa Lubian, Alessandro Cazzolaro, Fabrizio Mancin, Livia Giotta, Disma Mastrogiacomo, Ludovico Valli, Alessandra Saccani, Silke Krol, Marcella Bonchio, Mauro Carraro

Publikováno v: Frontiers in Chemistry, Vol 6 (2018)

The Keggin-type polyoxometalate [γ-SiW10O36]8− was covalently modified to obtain a bis-biotinylated conjugate able to bind avidin. Spectroscopic studies such as UV-vis, fluorimetry, circular dichroism, coupled to surface plasmon resonance techniqu

Externí odkaz: https://doaj.org/article/0bc1dc32b643494fb8d6b8119f9a240b

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Multifunctional, CD44v6-Targeted ORMOSIL Nanoparticles Enhance Drugs Toxicity in Cancer Cells

Autor: Venera Russo, Lucía Morillas-Becerril, Marta Trevisan, Elektra Peta, Luca Gabrielli, Elisa Lubian, Maria Grazia Ferlin, Paolo Scrimin, Luca Nodari, Luisa Barzon, Giorgio Palù, Ignazio Castagliuolo, Fabrizio Mancin

Publikováno v: Nanomaterials, Vol 10, Iss 2, p 298 (2020)
Nanomaterials (Basel) 10 (2020): 298-1–298-21. doi:10.3390/nano10020298
info:cnr-pdr/source/autori:Morillas-Becerril L.; Peta E.; Gabrielli L.; Russo V.; Lubian E.; Nodari L.; Ferlin M.G.; Scrimin P.; Palu G.; Barzon L.; Castagliuolo I.; Mancin F.; Trevisan M./titolo:Multifunctional, CD44v6-targeted ORMOSIL nanoparticles enhance drugs toxicity in cancer cells/doi:10.3390%2Fnano10020298/rivista:Nanomaterials (Basel)/anno:2020/pagina_da:298-1/pagina_a:298-21/intervallo_pagine:298-1–298-21/volume:10
Nanomaterials
Volume 10
Issue 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaede9502d6486c90fc764d03846ea52
https://www.mdpi.com/2079-4991/10/2/298

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C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes

Autor: Chiara Fedeli, Giulia Morgese, Emanuele Papini, Patrizia Polverino de Laureto, Elisa Lubian, Alessandra Geffner-Smith, Seyed Moein Moghimi, Edmondo M. Benetti, Regina Tavano, Silvia Visentin, Giorgio Arrigoni, Fabrizio Mancin, Luca Gabrielli, Fangfang Chen, Lin-Ping Wu, Dmitri Simberg

Publikováno v: ACS Nano. 12:5834-5847

Poly(2-methyl-2-oxazoline) (PMOXA) is an alternative promising polymer to poly(ethylene glycol) (PEG) for design and engineering of macrophage-evading nanoparticles (NPs). Although PMOXA-engineered NPs have shown comparable pharmacokinetics and in vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7b4f99ef4cbc1c8870e0a06d61bdbe
https://doi.org/10.1021/acsnano.8b01806

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The functional dissection of the plasma corona of SiO2-NPs spots histidine rich glycoprotein as a major player able to hamper nanoparticle capture by macrophages

Autor: Patrizia Polverino de Laureto, Emanuele Papini, Daniela Segat, Giorgia De Franceschi, Fabrizio Mancin, Regina Tavano, Luigi Bubacco, Elisa Lubian, Chiara Fedeli, Francesco Selvestrel

Publikováno v: Nanoscale. 7:17710-17728

A coat of strongly-bound host proteins, or hard corona, may influence the biological and pharmacological features of nanotheranostics by altering their cell-interaction selectivity and macrophage clearance. With the goal of identifying specific coron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49b956bfcda78a7b4a2049c95c80550
https://doi.org/10.1039/c5nr05290d

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Combined Action of Human Commensal Bacteria and Amorphous Silica Nanoparticles on the Viability and Immune Responses of Dendritic Cells

Autor: Regina Tavano, Emanuele Papini, Fabrizio Mancin, Giulia Malachin, Elisa Lubian

Dendritic cells (DCs) regulate the host-microbe balance in the gut and skin, tissues likely exposed to nanoparticles (NPs) present in drugs, food, and cosmetics. We analyzed the viability and the activation of DCs incubated with extracellular media (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e0b2a499420404817481e2e2be69bb
http://hdl.handle.net/11577/3259791

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Variations of the corona HDL:albumin ratio determine distinct effects of amorphous SiO2 nanoparticles on monocytes and macrophages in serum

Autor: Chiara Fedeli, Daniela Segat, de Laureto Pp, De Franceschi G, Fabrizio Mancin, Regina Tavano, Emanuele Papini, Elisa Lubian, Francesco Selvestrel

Publikováno v: Nanomedicine. 9:2481-2497

Aim: We investigated monocyte and macrophage death and cytokine production induced by amorphous silica nanoparticles (SiO2-NPs) to clarify the role of defined serum corona proteins. Materials & methods: The cytotoxic proinflammatory effects of SiO2-N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaee1a036dd146eac32358dffcb27d81
https://doi.org/10.2217/nnm.14.22

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Amphiphilic, hydrophilic, or hydrophobic synthetic bacteriochlorins in biohybrid light-harvesting architectures: consideration of molecular designs

Autor: Paul A. Loach, Christine Kirmaier, Jieying Jiao, David F. Bocian, Jonathan S. Lindsey, Michelle A. Harris, M. Phani Pavan, Jianbing Jiang, Kanumuri Ramesh Reddy, Dewey Holten, Elisa Lubian, Dariusz M. Niedzwiedzki, Pamela S. Parkes-Loach

Publikováno v: Photosynthesis Research. 122:187-202

Biohybrid light-harvesting architectures can be constructed that employ native-like bacterial photosynthetic antenna peptides as a scaffold to which synthetic chromophores are attached to augment overall spectral coverage. Synthetic bacteriochlorins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ca626d476a05c35ae378c4fde1bab5
https://doi.org/10.1007/s11120-014-0021-9

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PEGylation of ORMOSIL nanoparticles differently modulates the in vitro toxicity toward human lung cells

Autor: Francesco Selvestrel, Francesca Moret, Elena Reddi, Maddalena Mognato, Fabrizio Mancin, Elisa Lubian, Lucia Celotti

Publikováno v: Archives of Toxicology. 89:607-620

ORganically MOdified SILica (ORMOSIL) nanoparticles (NPs) appear promising carriers for the delivery of drugs to target tissues but concerns on possible cytotoxic effects exist. Here, we studied the in vitro responses to ORMOSIL NPs in different type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfc9c4f0d555905189ccba83c040316
https://doi.org/10.1007/s00204-014-1273-z

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Hydrophilic tetracarboxy bacteriochlorins for photonics applications

Autor: M. Phani Pavan, Tuba Sahin, Jianbing Jiang, Elisa Lubian, Jonathan S. Lindsey, Pothiappan Vairaprakash, Kanumuri Ramesh Reddy

Publikováno v: Org. Biomol. Chem.. 12:86-103

Bacteriochlorins absorb strongly in the near-infrared (NIR, 700-900 nm) region and hence are well suited for photophysical studies and photomedical applications, yet such endeavors heretofore have been largely limited by the intrinsic lipophilicity o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf0c3652a6244757bb422d228e37964
https://doi.org/10.1039/c3ob41791c

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