Staphylococcus aureus populations from the gut and the blood are not distinguished by virulence traits—a critical role of host barrier integrity

Autor: Elisa J. M. Raineri, Sandra Maaß, Min Wang, Siobhan Brushett, Laura M. Palma Medina, Neus Sampol Escandell, Dania Altulea, Erwin Raangs, Anne de Jong, Elias Vera Murguia, Edward J. Feil, Alex W. Friedrich, Girbe Buist, Dörte Becher, Silvia García-Cobos, Natacha Couto, Jan Maarten van Dijl

Publikováno v: Microbiome, Vol 10, Iss 1, Pp 1-23 (2022)

Abstract Background The opportunistic pathogen Staphylococcus aureus is an asymptomatically carried member of the microbiome of about one third of the human population at any given point in time. Body sites known to harbor S. aureus are the skin, nas

Externí odkaz: https://doaj.org/article/9e7563a4962a43e8aeb188e6eb331b06

Time-resolved analysis of Staphylococcus aureus invading the endothelial barrier

Autor: Harita Yedavally, Anna Salvati, Elisa J M Raineri, Jan Maarten van Dijl

Publikováno v: Virulence, 11(1), 1623-1639. Taylor & Francis Group
Virulence, Vol 11, Iss 1, Pp 1623-1639 (2020)
Virulence

Staphylococcus aureus is a leading cause of infections world-wide. Once this pathogen has reached the bloodstream, it can invade different parts of the human body by crossing the endothelial barrier. Infected endothelial cells may be lysed by bacteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa39f6b841250246b5f08cd475e4037
https://research.rug.nl/en/publications/881ca682-f964-48f6-b4aa-350afb23da78

Multimodal imaging guides surgical management in a preclinical spinal implant infection model

Autor: Jason T. Lee, Charles Zamilpa, Nicholas M. Bernthal, Tove Olafsen, Gideon Blumstein, Kellyn R. Hori, Stephen D. Zoller, Zachary D. C. Burke, Howard Y. Park, Julie Czupryna, Craig McMannus, Jan Maarten van Dijl, William L. Sheppard, Jeffery F. Miller, Jen-Chieh Tseng, Mafalda Bispo, Francisco Romero Pastrana, Elisa J M Raineri, Christopher D. Hamad, Lloyd S. Miller, Kevin P. Francis

Publikováno v: JCI insight, vol 4, iss 3
JCI Insight, 4(3):124813. AMER SOC CLINICAL INVESTIGATION INC
JCI Insight

Spine implant infections portend disastrous outcomes, as diagnosis is challenging and surgical eradication is at odds with mechanical spinal stability. Current imaging modalities can detect anatomical alterations and anomalies but cannot differentiat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e82ebe1fcefa8e7e023da0224e5b49
https://escholarship.org/uc/item/0g99b21x

Fighting Staphylococcus aureus infections with light and photoimmunoconjugates

Autor: Andrea Anaya-Sanchez, Marleen van Oosten, Francisco Romero Pastrana, Marina López-Álvarez, Sabrina Suhani, Mafalda Bispo, Kevin P. Francis, Wiktor Szymanski, Jan Maarten van Dijl, Elisa J M Raineri, Gooitzen M. van Dam, Girbe Buist, Marjolein Heuker, Alexander R. Horswill

Publikováno v: JCI Insight, Vol 5, Iss 22 (2020)
JCI Insight
JCI Insight, 5(22). AMER SOC CLINICAL INVESTIGATION INC
JCI Insight, 5(22):139512. AMER SOC CLINICAL INVESTIGATION INC

Infections caused by multidrug-resistant Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), are responsible for high mortality and morbidity worldwide. Resistant lineages were previously confined to hospitals but are now also c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f14600a6852ec293362f7b13c20377a