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pro vyhledávání: '"Elisa Imperi"'
Autor:
Maria Paola Martelli, Alessia Santi, Guido Russo, Roberta Mannucci, Alessandra Pucciarini, Elisa Imperi, Ariele Spanhol-Rosseto, Brunangelo Falini, Elisabetta Fortini, Valentina Pettirossi, Enrico Tiacci, Gianluca Schiavoni, Barbara Bigerna, Ludger Klein-Hitpass, Paolo Sportoletti
Hairy cell leukemia (HCL) shows unique clinicopathological and biological features. HCL responds well to purine analogs but relapses are frequent and novel therapies are required. BRAF-V600E is the key driver mutation in HCL and distinguishes it from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384fd1805651d19f412921504a880294
Autor:
Barbara Bigerna, Valentina Pettirossi, Enrico Tiacci, Ildo Nicoletti, Maria Paola Martelli, Roberta Mannucci, Elisabetta Fortini, Guido Russo, Alessia Santi, Elisa Imperi, Alessandra Pucciarini, Brunangelo Falini
Publikováno v:
Blood. 122:3064-3064
Background Hairy cell leukemia (HCL) is a peripheral B-cell neoplasm with indolent clinical course and peculiar morphology and phenotype. Recently, we identified the BRAF-V600E kinase mutation as the genetic lesion underlying HCL and distinguishing i